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Translational Medicine, 


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Название:  Translational Medicine
ISBN: 9780367386177
Издательство: Taylor&Francis
Классификация:



ISBN-10: 0367386178
Обложка/Формат: Paperback
Страницы: 244
Вес: 0.45 кг.
Дата издания: 20.12.2019
Язык: English
Размер: 154 x 233 x 15
Читательская аудитория: Tertiary education (us: college)
Основная тема: Statistical Theory & Methods
Подзаголовок: Strategies and Statistical Methods
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

Examines Critical Decisions for Transitioning Lab Science to a Clinical SettingThe development of therapeutic pharmaceutical compounds is becoming more expensive, and the success rates for getting such treatments approved for marketing and to the patients is decreasing. As a result, translational medicine (TM) is becoming increasingly important in the healthcare industry - a means of maximizing the consideration and use of information collected as compounds transition from initial lab discovery, through pre-clinical testing, early clinical trials, and late confirmatory studies that lead to regulatory approval of drug release to patients.

Translational Medicine: Strategies and Statistical Methods suggests a process for transitioning from the initial lab discovery to the patients bedside with minimal disconnect and offers a comprehensive review of statistical design and methodology commonly employed in this bench-to-bedside research.

Documents Alternative Research Approaches for Faster and More Accurate Data Judgment CallsElaborating on how to introduce TM into clinical studies, this authoritative work presents a keen approach to building, executing, and validating statistical models that consider data from various phases of development. It also delineates a truly translational example to help bolster understanding of discussed concepts.

This comprehensive guide effectively demonstrates how to overcome obstacles related to successful TM practice. It contains invaluable information for pharmaceutical scientists, research executives, clinicians, and biostatisticians looking to expedite successful implementation of this important process.



Mesenchymal Stromal Cells

Автор: Peiman, Hematti
Название: Mesenchymal Stromal Cells
ISBN: 0128028262 ISBN-13(EAN): 9780128028261
Издательство: Elsevier Science
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Цена: 97690.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Mesenchymal Stromal Cells: Translational Pathways to Clinical Adoption provides the latest information on the necessary steps for successful production of stem cells for a clinical trial. Written by professionals with hands-on experience in bringing MSC therapies to the clinic, and building on the biology and mechanisms of action, this unique book covers the development and production of clinical-grade products that are suitable for use in humans. From design of a cell production facility, to obtaining regulatory approval and reimbursement issues, it is a useful guide for researchers and administrators across biomedical research.

Methodologies of Multi-Omics Data Integration and Data Mining

Автор: Ning
Название: Methodologies of Multi-Omics Data Integration and Data Mining
ISBN: 9811982120 ISBN-13(EAN): 9789811982125
Издательство: Springer
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Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book features multi-omics big-data integration and data-mining techniques. In the omics age, paramount of multi-omics data from various sources is the new challenge we are facing, but it also provides clues for several biomedical or clinical applications. This book focuses on data integration and data mining methods for multi-omics research, which explains in detail and with supportive examples the “What”, “Why” and “How” of the topic. The contents are organized into eight chapters, out of which one is for the introduction, followed by four chapters dedicated for omics integration techniques focusing on several omics data resources and data-mining methods, and three chapters dedicated for applications of multi-omics analyses with application being demonstrated by several data mining methods. This book is an attempt to bridge the gap between the biomedical multi-omics big data and the data-mining techniques for the best practice of contemporary bioinformatics and the in-depth insights for the biomedical questions. It would be of interests for the researchers and practitioners who want to conduct the multi-omics studies in cancer, inflammation disease, and microbiome researches.

Traditional Chinese Medicine and Diseases

Автор: Ning
Название: Traditional Chinese Medicine and Diseases
ISBN: 9811947732 ISBN-13(EAN): 9789811947735
Издательство: Springer
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Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on the multi-omics big-data integration, the data-mining techniques and the cutting-edge omics researches in principles and applications for a deep understanding of Traditional Chinese Medicine (TCM) and diseases from the following aspects: (1) Basics about multi-omics data and analytical methods for TCM and diseases. (2) The needs of omics studies in TCM researches, and the basic background of omics research in TCM and disease. (3) Better understanding of the multi-omics big-data integration techniques. (4) Better understanding of the multi-omics big-data mining techniques, as well as with different applications, for most insights from these omics data for TCM and disease researches. (5) TCM preparation quality control for checking both prescribed and unexpected ingredients including biological and chemical ingredients. (6) TCM preparation source tracking. (7) TCM preparation network pharmacology analysis. (8) TCM analysis data resources, web services, and visualizations. (9) TCM geoherbalism examination and authentic TCM identification. Traditional Chinese Medicine has been in existence for several thousands of years, and only in recent tens of years have we realized that the researches on TCM could be profoundly boosted by the omics technologies. Devised as a book on TCM and disease researches in the omics age, this book has put the focus on data integration and data mining methods for multi-omics researches, which will be explained in detail and with supportive examples the “What”, “Why” and “How” of omics on TCM related researches. It is an attempt to bridge the gap between TCM related multi-omics big data, and the data-mining techniques, for best practice of contemporary bioinformatics and in-depth insights on the TCM related questions.

Biomedical Translational Research

Автор: Sobti
Название: Biomedical Translational Research
ISBN: 9811692343 ISBN-13(EAN): 9789811692345
Издательство: Springer
Рейтинг:
Цена: 186330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book, which is the third volume of Biomedical translational research, focuses on the fundamental role of biomedical research in developing new medicinal products. It emphasizes the importance of understanding biological and pathophysiological mechanisms underlying the disease to discover and develop new biological agents. The book uniquely explores the genomic computational integrative approach for drug repositioning. Further, it discusses the health benefits of nutraceuticals and their application in human diseases. Further, the book comprehensively reviews different computational approaches that employ GWAS data to guide drug repositioning. Finally, it summarizes the major challenges in drug development and the strategies for the rational design of the next generation more effective but less toxic therapeutic agents.

Analysis of Protein Post-Translational Modifications by Mass Spectrometry

Автор: Griffiths
Название: Analysis of Protein Post-Translational Modifications by Mass Spectrometry
ISBN: 1119045851 ISBN-13(EAN): 9781119045854
Издательство: Wiley
Рейтинг:
Цена: 119270.00 T
Наличие на складе: Поставка под заказ.

Translational Medicine

Автор: Mittra, James
Название: Translational Medicine
ISBN: 9814316997 ISBN-13(EAN): 9789814316996
Издательство: Taylor&Francis
Рейтинг:
Цена: 117390.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Translational Medicine

Автор: Cosmatos, Dennis
Название: Translational Medicine
ISBN: 1584888725 ISBN-13(EAN): 9781584888727
Издательство: Taylor&Francis
Рейтинг:
Цена: 117390.00 T
Наличие на складе: Нет в наличии.

Translational Medicine

Автор: Cavagnaro, Joy A.
Название: Translational Medicine
ISBN: 0367644274 ISBN-13(EAN): 9780367644277
Издательство: Taylor&Francis
Рейтинг:
Цена: 173530.00 T
Наличие на складе: Нет в наличии.

Animal And Translational Models For Cns Drug Discovery: Reward Deficit Disorders

Автор: McArthur, Robert A.
Название: Animal And Translational Models For Cns Drug Discovery: Reward Deficit Disorders
ISBN: 0123738601 ISBN-13(EAN): 9780123738608
Издательство: Elsevier Science
Рейтинг:
Цена: 79730.00 T
Наличие на складе: Поставка под заказ.
Описание: Suitable for researchers in academia and pharmaceutical industry who use animal models in research and development of drugs for reward deficit disorders, this title identifies and provides common endpoints between species that can serve to inform the clinic and bench with information needed to accelerate clinically-effective CNS drug discovery.

Animal And Translational Models For Cns Drug Discovery: Psychiatric Disorders

Автор: McArthur, Robert A.
Название: Animal And Translational Models For Cns Drug Discovery: Psychiatric Disorders
ISBN: 0123738563 ISBN-13(EAN): 9780123738561
Издательство: Elsevier Science
Рейтинг:
Цена: 79730.00 T
Наличие на складе: Поставка под заказ.
Описание: Suitable for researchers in academia and pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders, this title identifies and provides common endpoints between species that can serve to inform the clinic and the bench with information needed to accelerate clinically-effective CNS drug discovery.

Animal And Translational Models For Cns Drug Discovery: Neurological Disorders

Автор: McArthur, Robert A.
Название: Animal And Translational Models For Cns Drug Discovery: Neurological Disorders
ISBN: 0123738555 ISBN-13(EAN): 9780123738554
Издательство: Elsevier Science
Рейтинг:
Цена: 70730.00 T
Наличие на складе: Поставка под заказ.
Описание: Suitable for researchers in academia and pharmaceutical industry who use animal models in research and development of drugs for neurological disorders, this title identifies and provides common endpoints between species that can serve to inform the clinic and the bench with information needed to accelerate clinically-effective CNS drug discovery.

Methodologies of Multi-Omics Data Integration and Data Mining

Автор: Ning
Название: Methodologies of Multi-Omics Data Integration and Data Mining
ISBN: 9811982090 ISBN-13(EAN): 9789811982095
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book features multi-omics big-data integration and data-mining techniques. In the omics age, paramount of multi-omics data from various sources is the new challenge we are facing, but it also provides clues for several biomedical or clinical applications. This book focuses on data integration and data mining methods for multi-omics research, which explains in detail and with supportive examples the “What”, “Why” and “How” of the topic. The contents are organized into eight chapters, out of which one is for the introduction, followed by four chapters dedicated for omics integration techniques focusing on several omics data resources and data-mining methods, and three chapters dedicated for applications of multi-omics analyses with application being demonstrated by several data mining methods. This book is an attempt to bridge the gap between the biomedical multi-omics big data and the data-mining techniques for the best practice of contemporary bioinformatics and the in-depth insights for the biomedical questions. It would be of interests for the researchers and practitioners who want to conduct the multi-omics studies in cancer, inflammation disease, and microbiome researches.


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