Translational Medicine, Cavagnaro, Joy A.

Автор: Erika Ruiz-Garcia; Horacio Astudillo-de la Vega
Название: Translational Research and Onco-Omics Applications in the Era of Cancer Personal Genomics
ISBN: 3030240991 ISBN-13(EAN): 9783030240998
Издательство: Springer
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Цена: 93160.00 T
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Описание: Being a complex disease that affects millions of people world over, cancer research has assumed great significance. Translational cancer research transforms scientific discoveries in the laboratory into clinical application to reduce incidence of cancer, morbidity and mortality. On the other hand, personalized medicine in cancer is the concept that selection of a treatment should be tailored according to the individual patient’s specific genomic characteristics, including mutations, chromosomal aberrations, protein interactions, and SNPs, and even more, taking into account the inmume system, the metabolism and maybe in the next future also the microbiome.

Автор: McArthur, Robert A.
Название: Animal And Translational Models For Cns Drug Discovery: Psychiatric Disorders
ISBN: 0123738563 ISBN-13(EAN): 9780123738561
Издательство: Elsevier Science
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Цена: 79730.00 T
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Описание: Suitable for researchers in academia and pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders, this title identifies and provides common endpoints between species that can serve to inform the clinic and the bench with information needed to accelerate clinically-effective CNS drug discovery.

Автор: McArthur, Robert A.
Название: Animal And Translational Models For Cns Drug Discovery: Reward Deficit Disorders
ISBN: 0123738601 ISBN-13(EAN): 9780123738608
Издательство: Elsevier Science
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Цена: 79730.00 T
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Описание: Suitable for researchers in academia and pharmaceutical industry who use animal models in research and development of drugs for reward deficit disorders, this title identifies and provides common endpoints between species that can serve to inform the clinic and bench with information needed to accelerate clinically-effective CNS drug discovery.

Автор: Ena Ray Banerjee
Название: Perspectives in Translational Research in Life Sciences and Biomedicine
ISBN: 9811355118 ISBN-13(EAN): 9789811355110
Издательство: Springer
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Цена: 93160.00 T
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Описание: The studies and discourses described touch upon topics that explore biodiversity for the development of disease models, toxicity studies, developmental studies, and harvesting of bioactive compounds for alternative income generation and poverty alleviation, and as a result, bring about economic and ecologic sustainability.

Автор: Teschendorff
Название: Computational and Statistical Epigenomics
ISBN: 9402403434 ISBN-13(EAN): 9789402403435
Издательство: Springer
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Цена: 93160.00 T
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Описание: This book introduces the reader to modern computational and statistical tools for translational epigenomics research. Over the last decade, epigenomics has emerged as a key area of molecular biology, epidemiology and genome medicine. Epigenomics not only offers us a deeper understanding of fundamental cellular biology, but also provides us with the basis for an improved understanding and management of complex diseases. From novel biomarkers for risk prediction, early detection, diagnosis and prognosis of common diseases, to novel therapeutic strategies, epigenomics is set to play a key role in the personalized medicine of the future. In this book we introduce the reader to some of the most important computational and statistical methods for analyzing epigenomic data, with a special focus on DNA methylation. Topics include normalization, correction for cellular heterogeneity, batch effects, clustering, supervised analysis and integrative methods for systems epigenomics. This book will be of interest to students and researchers in bioinformatics, biostatistics, biologists and clinicians alike. Dr. Andrew E. Teschendorff is Head of the Computational Systems Genomics Lab at the CAS-MPG Partner Institute for Computational Biology, Shanghai, China, as well as an Honorary Research Fellow at the UCL Cancer Institute, University College London, UK.

Автор: Pierre Busson
Название: Nasopharyngeal Carcinoma
ISBN: 1493954954 ISBN-13(EAN): 9781493954957
Издательство: Springer
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Цена: 148010.00 T
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Описание: This book takes a "translational medicine and biology" approach to Nasopharyngeal Carcinoma, developing knowledge from basic science towards diagnostic and therapeutic applications and reciprocally proposing new questions for basic scientists.

Автор: Villaverde, A
Название: Nanoparticles In Translational Science And Medicine,104
ISBN: 0124160204 ISBN-13(EAN): 9780124160200
Издательство: Elsevier Science
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Цена: 140360.00 T
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Описание: Explores advances in basic research on nanoparticles in translational science and medicine and how this knowledge is leading to advances in the various fields. This title provides a forum for discussion of new discoveries, approaches, and ideas. It is suitable for researchers involved in molecular biology and related fields.

Автор: Per Hellman
Название: Primary Aldosteronism
ISBN: 1493946226 ISBN-13(EAN): 9781493946228
Издательство: Springer
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Цена: 130590.00 T
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Описание: Primary Aldosteronism (PA) is a disease caused by the overproduction of aldosterone hormone from the adrenal glands. PA causes hypertension and the majority with this disease are undiagnosed for PA. In 2011, a breakthrough in the genetic derangements came, identifying a mutated potassium channel gene - KCNJ5 - in about 40% of PA with adenoma.

Автор: Sadegh Babashah
Название: Cancer Stem Cells: Emerging Concepts and Future Perspectives in Translational Oncology
ISBN: 3319210297 ISBN-13(EAN): 9783319210292
Издательство: Springer
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Цена: 158380.00 T
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Описание: The concept of cancer stem cells has great clinical implications. Although there are some huge gaps in our current understanding of the role played by cancer stem cells in cancer biology, a growing body of evidence provides strong support for the principal functions of these cells in tumorigenesis.

Автор: Xiangdong Wang
Название: Bioinformatics of Human Proteomics
ISBN: 9400758103 ISBN-13(EAN): 9789400758100
Издательство: Springer
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Цена: 200260.00 T
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Описание: Full of useful practical designs and methodologies, this book discusses developing techniques and applications in the field of protein bioinformatics, featuring contributions from expert researchers on topics including protein analysis and drug development.

Автор: Grune, Tilman
Название: The Proteasomal System In Aging And Disease,109
ISBN: 0123978637 ISBN-13(EAN): 9780123978639
Издательство: Elsevier Science
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Цена: 132500.00 T
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Описание: Discusses research of proteasomes and proteasome-associated proteins and cellular systems. This title also discusses the knowledge of the structure, function, and regulation of the proteasomal system. It describes the role of the proteasome in aging and disease.

Автор: Turksen
Название: Cell Biology and Translational Medicine, Volume 13
ISBN: 3030790606 ISBN-13(EAN): 9783030790608
Издательство: Springer
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Цена: 102480.00 T
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Описание: Much research has focused on the basic cellular and molecular biological aspects of stem cells. Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical studies. However, more work is needed if the potential is to be realized for improvement of the lives and well-being of patients with numerous diseases and conditions. This book series 'Cell Biology and Translational Medicine (CBTMED)' as part of SpringerNature’s longstanding and very successful Advances in Experimental Medicine and Biology book series, has the goal to accelerate advances by timely information exchange. Emerging areas of regenerative medicine and translational aspects of stem cells are covered in each volume. Outstanding researchers are recruited to highlight developments and remaining challenges in both the basic research and clinical arenas. This current book is the thirteenth volume of a continuing series.