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Animal And Translational Models For Cns Drug Discovery: Neurological Disorders, McArthur, Robert A.


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Автор: McArthur, Robert A.
Название:  Animal And Translational Models For Cns Drug Discovery: Neurological Disorders
ISBN: 9780123738554
Издательство: Elsevier Science
Классификация:


ISBN-10: 0123738555
Обложка/Формат: Hardback
Страницы: 416
Вес: 0.96 кг.
Дата издания: 18.11.2008
Язык: English
Размер: 268 x 193 x 28
Читательская аудитория: Professional & vocational
Основная тема: Pharma Sci&Pha
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Европейский союз
Описание: Suitable for researchers in academia and pharmaceutical industry who use animal models in research and development of drugs for neurological disorders, this title identifies and provides common endpoints between species that can serve to inform the clinic and the bench with information needed to accelerate clinically-effective CNS drug discovery.

Animal And Translational Models For Cns Drug Discovery: Psychiatric Disorders

Автор: McArthur, Robert A.
Название: Animal And Translational Models For Cns Drug Discovery: Psychiatric Disorders
ISBN: 0123738563 ISBN-13(EAN): 9780123738561
Издательство: Elsevier Science
Рейтинг:
Цена: 79730.00 T
Наличие на складе: Поставка под заказ.
Описание: Suitable for researchers in academia and pharmaceutical industry who use animal models in research and development of drugs for psychiatric disorders, this title identifies and provides common endpoints between species that can serve to inform the clinic and the bench with information needed to accelerate clinically-effective CNS drug discovery.

Animal And Translational Models For Cns Drug Discovery: Reward Deficit Disorders

Автор: McArthur, Robert A.
Название: Animal And Translational Models For Cns Drug Discovery: Reward Deficit Disorders
ISBN: 0123738601 ISBN-13(EAN): 9780123738608
Издательство: Elsevier Science
Рейтинг:
Цена: 79730.00 T
Наличие на складе: Поставка под заказ.
Описание: Suitable for researchers in academia and pharmaceutical industry who use animal models in research and development of drugs for reward deficit disorders, this title identifies and provides common endpoints between species that can serve to inform the clinic and bench with information needed to accelerate clinically-effective CNS drug discovery.

Translational Neuroimaging

Автор: McArthur, Robert A.
Название: Translational Neuroimaging
ISBN: 0123869455 ISBN-13(EAN): 9780123869456
Издательство: Elsevier Science
Рейтинг:
Цена: 148220.00 T
Наличие на складе: Поставка под заказ.
Описание: Examines the translational role of neuroimaging in model development from preclinical animal models, to human experimental medicine, and finally to clinical studies. This book provides common endpoints between species that can serve to inform the clinic and bench with the information needed to accelerate clinically-effective CNS drug discovery.

Translational neuroscience

Название: Translational neuroscience
ISBN: 1489976523 ISBN-13(EAN): 9781489976529
Издательство: Springer
Рейтинг:
Цена: 174150.00 T
Наличие на складе: Поставка под заказ.
Описание:

Chapter 1 - Introduction - Mark H. Tuszynski

Section 1: Molecular Approaches

Chapter 2 - Gene Therapy of CNS Disorders using Recombinant AAV vectors - Giridhar Murlidharan, R. Jude Samulski and Aravind Asokan

Chapter 3 - NGF and BDNF Gene Therapy for Alzheimer's Disease - Alan H. Nagahara and Mark H. Tuszynski

Chapter 4 - GDNF and AADC Gene Therapy for Parkinson's Disease - Krystof Bankiewicz, Waldy San Sebastian, Lluis Samaranch and John Forsayeth

Chapter 5 - GAD Gene Therapy for Parkinson's Disease - Michael G. Kaplitt and Matthew J. During

Chapter 6 - Anti-sense Oligonucleotides

for Amyotrophic Lateral Sclerosis - Wade K. Self and Timothy M. Miller

Chapter 7 - Gene therapy for Inborn Errors of Metabolism: Batten Disease - Dolan Sondhi, Ronald G. Crystal and Stephen M. Kaminsky

Chapter 8 - Gene Therapy for Spinal Cord Injury - Ioana Goganau and Armin Blesch

Chapter 9 - Gene Therapy for Epilepsy - Thomas J. McCown

Chapter 10 - Gene therapy for Pain - Darren Wolfe, David Krisky, James Goss, James Wechuck, Marina Mata and David J. Fink

Section 2: Cellular Approaches

Chapter 11 - Stem Cells for Parkinson's Disease - Andrйs Bratt-Leal and Jeanne F. Loring

quot;serif"">Chapter 12 - Could Stem Cells be used to treat or model Alzheimer's Disease? - Edsel M. Abud and Mathew Blurton-Jones

Chapter 13 - Stem cells for Amyotrophic Late

ral Sclerosis - Anthony Donsante, Lindsey Nicole Urquia and Nicholas M. Boulis

Chapter 14 - Stem cells for Multiple Sclerosis - Pamela Sarkar and Neil Scolding

Chapter 15 - Cell Therapy for Pediatric Disorders of Glia - Joana M. Osorio and Steven A. Goldman

Chapter 16 - Neural Stem Cells for Spinal Cord Injury - Paul Lu, Ruhel Amhad

le="mso-bidi-font-size:12.0pt;font-family: "Times New Roman","serif""> and Mark H. Tuszynski

Chapter 17 - Marrow-derived Mesenchymal Stromal Cells in the Treatment of Stroke - Steve C. Cramer

Chapter 18 - Glioma Stem Cells - Regina Teresa Martuscello, Brent Reynolds and Santosh Kesari

Section 3: Novel Pharmacological Approaches

Chapter 19 - Discovery of Potent Gamma Secretase Modulators for the Treatment of Alzheimer's Disease - Kevin D. Rynearson, Rudolph E. Tanzi and Steven L. Wagner

Chapter 20 - Blocking the Nogo-A signalling pathway to promote regeneration and pla

sticity after spinal cord injury and stroke -

tachment: initial; background-size: initial; background-origin: initial; background-clip: initial; background-position: initial; background-repeat: initial;">Anna Magdalena Guzik-Kornacka, Flуra Vajda, Martin E. Schwab

Chapter 21 - Intrinsic neuronal mechanisms in axon regeneration after spinal cord injury - Fengfeng Bei and Zhigang He

Chapter 22 - Voltage-gated ion channels as molecula

r targe

ts for

pain -

Gerald

W. Zamponi, Chongyang Han and Stephen G. Waxman

Section 4: Activity-Dependent Plasticity and Neurorehabilitation

Chapter 23 - Rehabilitation-dependent neural plasticity after Spinal Cord Injury -

ot;,"serif"; mso-ansi-language: DE-CH">Volker Dietz, Lea Awai, Armin Curt and Grйgoire Courtine

Chapter 24 - Neural Prostheses for Neurotrauma - Arthur Prochazka

Chapter 25 - Why is Fu

nctional Electrical Stimulation Therapy Capable of Restoring Motor Function Following Severe Injury to the Central Nervous System? - Mary K. Nagai, Cesar Marquez-Chin and Milos R. Popovic

Chapter 26 - Deep Brain Stimulation for Neuropsychiatric Disorders - Ausaf A. Bari, Nicolas Kon Kam King, Nir Lipsman and Andres M. Lozano

Chapter 27 - Novel Interventions for Stroke: Nervous System Cooling - Patrick D. Lyden, Jessica Lamb and Padmesh S. Rajput

Chap

Modern cns drug discovery

Название: Modern cns drug discovery
ISBN: 3030623505 ISBN-13(EAN): 9783030623500
Издательство: Springer
Рейтинг:
Цена: 51230.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system.

Modern CNS Drug Discovery

Автор: Schreiber
Название: Modern CNS Drug Discovery
ISBN: 303062353X ISBN-13(EAN): 9783030623531
Издательство: Springer
Рейтинг:
Цена: 51230.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This textbook provides a comprehensive overview of the currently used concepts, approaches and technologies in the discovery and development of new treatments for the full spectrum of disorders of the central nervous system.

Animal Models of Acute Neurological Injury

Автор: Chen
Название: Animal Models of Acute Neurological Injury
ISBN: 3030160807 ISBN-13(EAN): 9783030160807
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The second edition continues to offer the research community tested approaches for this area of investigation. As with the first edition, top experts have developed and contributed these animal models.

Therapeutic Intranasal Delivery for Stroke and Neurological Disorders

Автор: Chen
Название: Therapeutic Intranasal Delivery for Stroke and Neurological Disorders
ISBN: 3030167135 ISBN-13(EAN): 9783030167134
Издательство: Springer
Рейтинг:
Цена: 121110.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In the last 10 years, intranasal delivery of various therapeutic compounds including small chemicals, large proteins, and even stem cells has proven to be very effective in bypassing the blood-brain-barrier and has led to some important advances in translational research for stroke and other neurological diseases.

Translational Neuroscience: Fundamental Approaches for Neurological Disorders

Автор: Tuszynski Mark H.
Название: Translational Neuroscience: Fundamental Approaches for Neurological Disorders
ISBN: 1493979426 ISBN-13(EAN): 9781493979424
Издательство: Springer
Рейтинг:
Цена: 204970.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

Chapter 1 - Introduction - Mark H. Tuszynski

Section 1: Molecular Approaches

Chapter 2 - Gene Therapy of CNS Disorders using Recombinant AAV vectors - Giridhar Murlidharan, R. Jude Samulski and Aravind Asokan

Chapter 3 - NGF and BDNF Gene Therapy for Alzheimer's Disease - Alan H. Nagahara and Mark H. Tuszynski

Chapter 4 - GDNF and AADC Gene Therapy for Parkinson's Disease - Krystof Bankiewicz, Waldy San Sebastian, Lluis Samaranch and John Forsayeth

Chapter 5 - GAD Gene Therapy for Parkinson's Disease - Michael G. Kaplitt and Matthew J. During

Chapter 6 - Anti-sense Oligonucleotides

for Amyotrophic Lateral Sclerosis - Wade K. Self and Timothy M. Miller

Chapter 7 - Gene therapy for Inborn Errors of Metabolism: Batten Disease - Dolan Sondhi, Ronald G. Crystal and Stephen M. Kaminsky

Chapter 8 - Gene Therapy for Spinal Cord Injury - Ioana Goganau and Armin Blesch

Chapter 9 - Gene Therapy for Epilepsy - Thomas J. McCown

Chapter 10 - Gene therapy for Pain - Darren Wolfe, David Krisky, James Goss, James Wechuck, Marina Mata and David J. Fink

Section 2: Cellular Approaches

Chapter 11 - Stem Cells for Parkinson's Disease - Andrйs Bratt-Leal and Jeanne F. Loring

quot;serif"">Chapter 12 - Could Stem Cells be used to treat or model Alzheimer's Disease? - Edsel M. Abud and Mathew Blurton-Jones

Chapter 13 - Stem cells for Amyotrophic Late

ral Sclerosis - Anthony Donsante, Lindsey Nicole Urquia and Nicholas M. Boulis

Chapter 14 - Stem cells for Multiple Sclerosis - Pamela Sarkar and Neil Scolding

Chapter 15 - Cell Therapy for Pediatric Disorders of Glia - Joana M. Osorio and Steven A. Goldman

Chapter 16 - Neural Stem Cells for Spinal Cord Injury - Paul Lu, Ruhel Amhad

le="mso-bidi-font-size:12.0pt;font-family: "Times New Roman","serif""> and Mark H. Tuszynski

Chapter 17 - Marrow-derived Mesenchymal Stromal Cells in the Treatment of Stroke - Steve C. Cramer

Chapter 18 - Glioma Stem Cells - Regina Teresa Martuscello, Brent Reynolds and Santosh Kesari

Section 3: Novel Pharmacological Approaches

Chapter 19 - Discovery of Potent Gamma Secretase Modulators for the Treatment of Alzheimer's Disease - Kevin D. Rynearson, Rudolph E. Tanzi and Steven L. Wagner

Chapter 20 - Blocking the Nogo-A signalling pathway to promote regeneration and pla

sticity after spinal cord injury and stroke -

tachment: initial; background-size: initial; background-origin: initial; background-clip: initial; background-position: initial; background-repeat: initial;">Anna Magdalena Guzik-Kornacka, Flуra Vajda, Martin E. Schwab

Chapter 21 - Intrinsic neuronal mechanisms in axon regeneration after spinal cord injury - Fengfeng Bei and Zhigang He

Chapter 22 - Voltage-gated ion channels as molecula

r targe

ts for

pain -

Gerald

W. Zamponi, Chongyang Han and Stephen G. Waxman

Section 4: Activity-Dependent Plasticity and Neurorehabilitation

Chapter 23 - Rehabilitation-dependent neural plasticity after Spinal Cord Injury -

ot;,"serif"; mso-ansi-language: DE-CH">Volker Dietz, Lea Awai, Armin Curt and Grйgoire Courtine

Chapter 24 - Neural Prostheses for Neurotrauma - Arthur Prochazka

Chapter 25 - Why is Fu

nctional Electrical Stimulation Therapy Capable of Restoring Motor Function Following Severe Injury to the Central Nervous System? - Mary K. Nagai, Cesar Marquez-Chin and Milos R. Popovic

Chapter 26 - Deep Brain Stimulation for Neuropsychiatric Disorders - Ausaf A. Bari, Nicolas Kon Kam King, Nir Lipsman and Andres M. Lozano

Chapter 27 - Novel Interventions for Stroke: Nervous System Cooling - Patrick D. Lyden, Jessica Lamb and Padmesh S. Rajput

Chap

Animal Models of Neurological Disorders

Автор: Puneet Kumar Bansal; Rahul Deshmukh
Название: Animal Models of Neurological Disorders
ISBN: 981135541X ISBN-13(EAN): 9789811355417
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Поставка под заказ.
Описание: It also includes numerous protocols for inducing single neurological diseases, thus fulfilling an urgent need for a book that makes specific procedures for neurological disorders available, so that specific disease can be induced in laboratories according to the availability of resources.

White Matter Injury in Stroke and CNS Disease

Название: White Matter Injury in Stroke and CNS Disease
ISBN: 1461491223 ISBN-13(EAN): 9781461491224
Издательство: Springer
Рейтинг:
Цена: 200260.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides systematic expert summaries of normal white matter morphology and details white matter injury following stroke and other CNS injuries. It features key notes and implementation advice from the experts.

Vascular Mechanisms in CNS Trauma

Автор: Lo
Название: Vascular Mechanisms in CNS Trauma
ISBN: 1461486890 ISBN-13(EAN): 9781461486893
Издательство: Springer
Рейтинг:
Цена: 200260.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Divided into three sections that cover molecular mechanisms, experimental models and methods, and clinical issues, this work on the vascular aspects of brain and spinal cord trauma features contributions from a wide range of research scientists and clinicians.


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