Автор: Farooqui, Akhlaq A. Название: Neurochemical Aspects of Alzheimer Disease ISBN: 0128099372 ISBN-13(EAN): 9780128099377 Издательство: Elsevier Science Рейтинг: Цена: 88650.00 T Наличие на складе: Поставка под заказ. Описание:
Neurochemical Aspects of Alzheimer's Disease provides a comprehensive overview of molecular aspects of risk factors, pathogenesis, biomarkers, and therapeutic strategies. The book focuses on molecular mechanisms and signal transduction processes associated with the pathogenesis, biomarkers, and therapeutic strategies of AD. The comprehensive and cutting edge information in this monograph may not only help in early detection of AD, but also promote discovery of new drugs to treat this chronic disease. Chapters discuss involvement of neural membrane phospholipids, sphingolipids, and cholesterol-derived lipid mediators, abnormal APP processing, and nucleic acid damage, risk factors, biomarker, and therapeutic strategies of Alzheimer's disease. This book is written for neurologists, neuroscientists, neurochemists, neuropharmacologists, and clinicianswho are interested in molecular mechanisms associated with the pathogenesis of age-related neurological disorders.
Автор: Hoa Huu Phuc Nguyen; M. Angela Cenci Название: Behavioral Neurobiology of Huntington`s Disease and Parkinson`s Disease ISBN: 3662524120 ISBN-13(EAN): 9783662524121 Издательство: Springer Рейтинг: Цена: 130590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Motor dysfunction and cognitive impairment are major symptoms in both Huntington`s Disease (HD) and Parkinson`s Disease (PD). This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.
Автор: Hoa Huu Phuc Nguyen; M. Angela Cenci Название: Behavioral Neurobiology of Huntington`s Disease and Parkinson`s Disease ISBN: 3662463431 ISBN-13(EAN): 9783662463437 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Motor dysfunction and cognitive impairment are major symptoms in both Huntington’s Disease (HD) and Parkinson’s Disease (PD). A breakthrough in HD research was the identification of the gene that causes this devastating monogenetic illness. Similarly, several genes were found to cause familial forms of PD. With their identification, a plethora of genetic animal models has been generated and has revolutionized the understanding of the pathobiology and pathophysiology of these disorders. The models allow us to study the earliest manifestations of the diseases behaviorally and neuropathologically and help us understand how they progress over time. Additionally, neurotoxic animal models are still of high interest to the PD field, as they are being used to study e.g. mitochondrial dysfunction in PD. This book focuses on animal models of both diseases and how they have helped and will continue to help understand the behavioral neurobiology in these disorders.
Автор: Sherman Howell Название: Living with Huntingtons Disease: Challenges, Perspectives and Quality of Life ISBN: 1536167290 ISBN-13(EAN): 9781536167290 Издательство: Nova Science Рейтинг: Цена: 89750.00 T Наличие на складе: Невозможна поставка. Описание: Living with Huntingtons Disease: Challenges, Perspectives and Quality of Life first discusses the variety of sleep disorders in Huntingtons Disease, as well as how sleep quality can be associated with other important clinical symptoms. Although Huntingtons disease is categorized as a movement disorder, the wide range of non-motor symptoms including cognitive impairment and behavioral abnormalities are considered by patients and their caregivers to be just as disabling as the motor symptoms. As such, the authors explore the importance of symptomatic treatment of Huntingtons disease-related symptoms. Following this, the emotional and communicational issues in Huntingtons disease and their interrelations are examined, including depressive symptomatology, anxiety, helplessness or anger, as well as verbal and non-verbal communication and assistive technology. Lastly, the authors describe current trends and efforts in gene therapy techniques and the improvements in health conditions of Huntingtons disease patients and their families.
Автор: Quarrell, Oliver (consultant In Clinical Genetics, Sheffield Children`s Hospital, Sheffield, Uk) Название: Huntington`s disease ISBN: 0198844387 ISBN-13(EAN): 9780198844389 Издательство: Oxford Academ Рейтинг: Цена: 19000.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Huntington`s disease (HD) is a genetically inherited condition resulting in severe nerve-cell damage in the brain. Written for patients and their families, this book explains the features of HD, the role of genetics, and advice on managing symptoms.
Автор: Quarrell, Oliver W J (consultant In Clinical Genetics, Sheffield Children`s Hospital, Sheffield, Uk) Название: Huntington`s disease ISBN: 0199212015 ISBN-13(EAN): 9780199212019 Издательство: Oxford Academ Рейтинг: Цена: 15830.00 T Наличие на складе: Поставка под заказ. Описание: Huntington`s disease affects 1 person in 10,000 but this figure is an underestimate because the immediate carer, spouse/partner and the close relatives at risk of developing this condition in the future are also affected. The new edition has been revised to include important new developments that have occurred in the field in recent years.
Автор: Lo, Donald C. Название: Neurobiology of Huntington`s Disease ISBN: 0849390001 ISBN-13(EAN): 9780849390005 Издательство: Taylor&Francis Рейтинг: Цена: 209270.00 T Наличие на складе: Нет в наличии.
Автор: Yang,X. William Название: Huntington`S Disease ISBN: 0323956726 ISBN-13(EAN): 9780323956727 Издательство: Elsevier Science Рейтинг: Цена: 129130.00 T Наличие на складе: Поставка под заказ.
Автор: Watt Название: A Clinico-Genetic Study of Psychiatric Disorder in Huntington`s Chorea ISBN: 0521459834 ISBN-13(EAN): 9780521459839 Издательство: Cambridge Academ Рейтинг: Цена: 40130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This report presents the findings of a study of people affected by Huntington`s chorea and their unaffected relatives, and in particular, of the incidence of functional psychiatric disorder of various types. It also considers the future prospects of the genetics of the condition
Автор: Khan, Tapan Название: Biomarkers in Alzheimer`s Disease ISBN: 0128048328 ISBN-13(EAN): 9780128048320 Издательство: Elsevier Science Рейтинг: Цена: 77470.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Biomarkers in Alzheimer's Disease provides a comprehensive overview of all modalities of Alzheimer's disease biomarkers, including neuroimaging, cerebrospinal fluid, genomic, and peripheral systems. Each chapter integrates molecular/cellular abnormality due to Alzheimer's disease and technological advancement of biomarkers techniques.
The book is ideal for clinical neuroscience and molecular/cellular neuroscience researchers, psychiatrists, and allied healthcare practitioners involved in the diagnosis and management of patients with cognitive impairment and Alzheimer's disease, and for differential diagnosis of Alzheimer's disease with other non-Alzheimer's dementia.
Автор: Lovestone Название: Biomarkers in Brain Disease ISBN: 1573317721 ISBN-13(EAN): 9781573317726 Издательство: Wiley Рейтинг: Цена: 103230.00 T Наличие на складе: Поставка под заказ. Описание: Advances in biomarker development are revolutionizing the way we study, diagnose and treat disease. However, progress in the development and use of biomarkers for diseases of the central nervous system has been limited by a number of difficulties -- including the inherent barriers associated with studying the brain.
Автор: Filipe Palavra; Fl?vio Reis; Daniela Marado; Arman Название: Biomarkers of Cardiometabolic Risk, Inflammation and Disease ISBN: 3319160176 ISBN-13(EAN): 9783319160177 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book discusses recent advances in the area of cardiometabolic risk biomarkers of chronic inflammatory and cardiovascular disorders.
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