Автор: Khan, Tapan Название: Biomarkers in Alzheimer`s Disease ISBN: 0128048328 ISBN-13(EAN): 9780128048320 Издательство: Elsevier Science Рейтинг: Цена: 77470.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Biomarkers in Alzheimer's Disease provides a comprehensive overview of all modalities of Alzheimer's disease biomarkers, including neuroimaging, cerebrospinal fluid, genomic, and peripheral systems. Each chapter integrates molecular/cellular abnormality due to Alzheimer's disease and technological advancement of biomarkers techniques.
The book is ideal for clinical neuroscience and molecular/cellular neuroscience researchers, psychiatrists, and allied healthcare practitioners involved in the diagnosis and management of patients with cognitive impairment and Alzheimer's disease, and for differential diagnosis of Alzheimer's disease with other non-Alzheimer's dementia.
Автор: Jacques Fantini Название: Brain Lipids in Synaptic Function and Neurological Disease ISBN: 0128001119 ISBN-13(EAN): 9780128001110 Издательство: Elsevier Science Рейтинг: Цена: 104410.00 T Наличие на складе: Невозможна поставка. Описание:
Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer's, Creutzfeldt-Jakob's and Parkinson's. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders.
Written to provide a "hands-on" approach for readers
Biochemical structures explained with molecular models, and molecular mechanisms explained with simple drawings
Step-by-step guide to memorize and draw lipid structures
Each chapter features a content summary, up-to-date references for additional study, and a key experiment with an explanation of the technique
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