Virus Entry Inhibitors, Jiang

Автор: Jiang
Название: Virus Entry Inhibitors
ISBN: 9811687013 ISBN-13(EAN): 9789811687013
Издательство: Springer
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Цена: 158380.00 T
Наличие на складе: Нет в наличии.
Описание: This book focuses on the important discoveries of the small molecule-, peptide-, and protein-based virus entry inhibitors and discusses advance of the development of different type of virus entry inhibitors as a novel class of antiviral drugs for treatment and prevention of viral infection. It includes entry inhibitors of HIV,HeV, NiV, RSV, EBOV, HCoV, HBV, HCV, HDV, HPV, flavivirus and influenza virus, so on. This book aims at providing an updated knowledge on virus entry inhibitors.

Автор: Taotao Zou
Название: Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(III), Gold(I) and Platinum(II)
ISBN: 9811006563 ISBN-13(EAN): 9789811006562
Издательство: Springer
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Цена: 95770.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Detailed chemical synthesis, in vitro and/or in vivo anti-cancer activities are clearly presented including: (i) a class of Au(III) complexes containing a highly fluorescent N^N^N ligand and NHC ligand that simultaneously act as fluorescent thiol "switch-on" probes and anti-cancer agents;

Автор: Maheshwari
Название: Natural Products as Enzyme Inhibitors
ISBN: 9811909318 ISBN-13(EAN): 9789811909313
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Chapters in this book cover topics such as plant-derived inhibitors of serine proteases, pancreatic lipase (PL) inhibitors from indigenous medicinal plants, amylase inhibitors and their applications in agriculture and food processing industries and advances in silico techniques used in the study of enzyme inhibitors.

Автор: Michel Pairet; Joanne van Ryn
Название: COX-2 Inhibitors
ISBN: 3034896077 ISBN-13(EAN): 9783034896078
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: COX-2 inhibitors are important drugs with analgesic and anti-inflammatory effects. This book presents both pre-clinical and clinical information and is important for clinicians interested in the latest information about this class of drugs, for researchers and for students in the field.

Автор: Lyubomir Vassilev; David Fry
Название: Small-Molecule Inhibitors of Protein-Protein Interactions
ISBN: 3642266703 ISBN-13(EAN): 9783642266706
Издательство: Springer
Рейтинг:
Цена: 174130.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this volume, the editors have collected the knowledgeable insights of researchers who have achieved success in addressing the difficult problem of inhibiting protein-protein interactions.

Автор: H.-W. Denker
Название: Implantation
ISBN: 3540084797 ISBN-13(EAN): 9783540084792
Издательство: Springer
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Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: On one hand, we have fairly well substantiated experimental and clinical evidence that the efficacy of these contraceptives lies with other factors as well, for example their influence on sperm migration and capacitation or their influence on the transportation of the unfertilized egg.

Автор: Robert B. Sim
Название: Activators and Inhibitors of Complement
ISBN: 9401052247 ISBN-13(EAN): 9789401052245
Издательство: Springer
Рейтинг:
Цена: 191560.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Автор: Tarun Jha
Название: Modeling Inhibitors of Matrix Metalloproteinases
ISBN: 1032289260 ISBN-13(EAN): 9781032289267
Издательство: Taylor&Francis
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Цена: 112290.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Автор: Nicola J. Curtin; Ricky A. Sharma
Название: PARP Inhibitors for Cancer Therapy
ISBN: 3319141503 ISBN-13(EAN): 9783319141503
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. PARP plays a pivotal role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer.

Автор: Alexey Larionov
Название: Resistance to Aromatase Inhibitors in Breast Cancer
ISBN: 3319382845 ISBN-13(EAN): 9783319382845
Издательство: Springer
Рейтинг:
Цена: 121890.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. The second section provides the detailed mechanisms of resistance to AIs, while the third section explores prediction of resistance and potential strategies to overcome resistance.

Автор: Maheshwari
Название: Natural Products as Enzyme Inhibitors
ISBN: 9811909342 ISBN-13(EAN): 9789811909344
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Нет в наличии.
Описание: This book provides an overview of the latest developments and future challenges in enzyme inhibitor research. It discusses the general enzyme inhibitory principles and mechanisms in enzyme activity regulation and application of enzyme inhibitors in different areas and sectors. The major areas of applications of enzyme inhibitors covered in this book are human health management, agriculture, food processing and research, which leads to drug discovery or enzyme activity mechanisms. The book also identifies the gaps in the existing knowledge and opens up new research ideas in this important area. Currently, most enzyme inhibitors are reported to inhibit various classes of enzymes. These enzyme inhibitors are the focus of the scientific community because they may answer an increasing array of questions in the research area of biological sciences, including biochemistry, medicine, physiology, pharmacy, agriculture, ecology etc. It also serves as a useful tool in the study of enzyme structures and reaction mechanisms and in the development of technologies in agriculture, food processing, and health management. Chapters in this book cover topics such as plant-derived inhibitors of serine proteases, pancreatic lipase (PL) inhibitors from indigenous medicinal plants, amylase inhibitors and their applications in agriculture and food processing industries and advances in silico techniques used in the study of enzyme inhibitors. The book will serve as a valuable resource for students and researchers in Life Sciences, agriculture, medicine, food processing, and allied industries.

Автор: Alexey Larionov
Название: Resistance to Aromatase Inhibitors in Breast Cancer
ISBN: 3319179713 ISBN-13(EAN): 9783319179711
Издательство: Springer
Рейтинг:
Цена: 130430.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Aromatase Inhibitors (AIs) treat postmenopausal estrogen receptor positive tumours, which constitute the majority of breast cancer patients. This comprehensive volume brings together the current knowledge from different relevant areas, including molecular mechanisms and translational aspects of drug resistance in AIs. Topics covered include research, experimental , and clinical data specifically focused on AI resistance in breast cancer. The volume will include three sections. The first section covers general knowledge about aromatase inhibitors, including regulation of aromatase genes, and structure and function of aromatase protein. The second section provides the detailed mechanisms of resistance to AIs, while the third section explores prediction of resistance and potential strategies to overcome resistance. Breast cancer is the most common female cancer and AIs significantly improve treatments outcomes compatibly to previously used endocrine treatments. However 10-15% of post-operative patients develop a relapse during adjuvant treatment with AIs; about 25-50% of the patients do not respond to AIs in neo-adjuvant or metastatic setting, and the majority of metastatic patients who initially respond develop resistance within 3 years. There is an important need to understand these mechanisms of resistance in order to develop methods of preventing or overcoming the resistance to AIs, which will ensure a more successful outcome in treating breast cancer.