Natural Products as Enzyme Inhibitors, Maheshwari

Автор: Martin Lorenz Stein
Название: NMR-Bioassay Guided Isolation of the Natural 20S Proteasome Inhibitors from Photorhabdus Luminescens
ISBN: 3319079131 ISBN-13(EAN): 9783319079134
Издательство: Springer
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Цена: 93160.00 T
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Описание: Martin Stein's thesis describes a novel methodology for natural product discovery. Due to its high degree of reproducibility, robustness and sensitivity, the technique can be utilized to detect even trace amounts of bioactive substances in heterogeneous matrices such as fermentation broths or crude organic extracts. This research is thus relevant for a large number of researchers working in natural product discovery. Applications of this novel NMR-based approach include suitable environmental triggers for the induction of biosynthetic machineries. The author demonstrates the extraordinary value of this approach by the successful isolation of two potent inhibitors of the pharmaceutically relevant proteasome core particle from the insect pathogen photorhabdus luminescens. This thesis has led to a number of publications in high-impact journals.

Автор: V. Kefeli; Bruno Borsari; M.V. Kalevitch
Название: Natural Growth Inhibitors and Phytohormones in Plants and Environment
ISBN: 9048161983 ISBN-13(EAN): 9789048161980
Издательство: Springer
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Цена: 174130.00 T
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Описание: Therefore, this effort proposes a more holistic approach to the study of plant physiology, in which the plant-soil interactions are discussed, with a profound description of different allelochemicals and their effects on plants growth.

Автор: Martin Lorenz Stein
Название: NMR-Bioassay Guided Isolation of the Natural 20S Proteasome Inhibitors from Photorhabdus Luminescens
ISBN: 331938399X ISBN-13(EAN): 9783319383996
Издательство: Springer
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Цена: 87060.00 T
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Описание: Martin Stein`s thesis describes a novel methodology for natural product discovery. The author demonstrates the extraordinary value of this approach by the successful isolation of two potent inhibitors of the pharmaceutically relevant proteasome core particle from the insect pathogen photorhabdus luminescens.

Автор: Xu, Jun-Ping (School of Molecular Science, Arizona State University)
Название: Cancer Inhibitors from Chinese Natural Medicines
ISBN: 1032097396 ISBN-13(EAN): 9781032097398
Издательство: Taylor&Francis
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Цена: 48990.00 T
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Описание: Nature is an attractive source of therapeutic and preventive compounds, and with such chemical diversity found in millions of species of plants, over 60% of currently used anticancer agents are derived from natural sources. Cancer Inhibitors from Chinese Natural Medicines summarizes new advancements in the experimental and clinical

Автор: Ganai, Shabir Ahmad
Название: Natural hdac inhibitors for epigenetic combating of cancer progression
ISBN: 1032279869 ISBN-13(EAN): 9781032279862
Издательство: Taylor&Francis
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Цена: 94930.00 T
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Описание: This Book entitled "Natural HDAC Inhibitors for Epigenetic Combating of Cancer Progression" deals only with HDAC inhibitors from natural origin including bacteria, fungi, marine organisms and notably from diverse plant sources.

Автор: Supuran Claudiu T., Capasso Clemente
Название: Zinc Enzyme Inhibitors: Enzymes from Microorganisms
ISBN: 3319834444 ISBN-13(EAN): 9783319834443
Издательство: Springer
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Цена: 214280.00 T
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Описание: An Elusive Task: A Clinically Useful Inhibitor of Metallo-β-Lactamases.- Inhibitors of Histidinol Dehydrogenase.- Botulinum Neurotoxin, Tetanus Toxin, and Anthrax Lethal Factor Countermeasures.- Inhibition and Activity Regulation of Bacterial Collagenases.- Fungal Carbonic Anhydrases and Their Inhibition.- Protozoan Carbonic Anhydrases.- Bacterial Carbonic Anhydrases.

Название: Pharmaceutical Biocatalysis
ISBN: 9814800619 ISBN-13(EAN): 9789814800617
Издательство: Taylor&Francis
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Цена: 197010.00 T
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Описание: The relationship between biocatalysis and the different areas of pharmaceutics is discussed in volumes 4 to 6 of Pan Stanford Series on Biocatalysis. Volume 4 provides an overview of the world market of therapeutic enzymes and enzyme inhibitors.

Автор: Mendel Friedman
Название: Nutritional and Toxicological Significance of Enzyme Inhibitors in Foods
ISBN: 1475700245 ISBN-13(EAN): 9781475700244
Издательство: Springer
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Цена: 93160.00 T
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Описание: Soybean protei ns are wi de 1 y used inhuman foods ina vari ety of forms, including baby formulas, flour, soy protein concentrates, soy protein isolates, soy sauces, textured soy fibers, and tofu.

Автор: Claudiu T. Supuran; Clemente Capasso
Название: Zinc Enzyme Inhibitors
ISBN: 3319461117 ISBN-13(EAN): 9783319461113
Издательство: Springer
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Цена: 204970.00 T
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Описание: Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Автор: Timothy D. Warner
Название: Endothelin and Its Inhibitors
ISBN: 3642632378 ISBN-13(EAN): 9783642632372
Издательство: Springer
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Цена: 46570.00 T
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Описание: With contributions by numerous experts

Автор: Utpal Chandra De, Priyambada Mishra, Prasenjit Rudra Pal, Ajoy Basak
Название: Non-peptide Inhibitors of Proprotein Convertase Subtilisin Kexins (PCSKs): An Overall Review of Existing and New Data
ISBN: 1615044744 ISBN-13(EAN): 9781615044740
Издательство: Mare Nostrum (Eurospan)
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Цена: 41580.00 T
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Описание: Provides an overall review of all non-peptide PCSK inhibitors so far reported in the literature along with those identified recently for the first time and not yet published. The potential implications of these molecules as biochemical, therapeutical, or clinical agents is also discussed.

Название: Viral Replication Enzymes and Their Inhibitors Part B, 50
ISBN: 032390016X ISBN-13(EAN): 9780323900164
Издательство: Elsevier Science
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Цена: 140360.00 T
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Описание: Viral Replication Enzymes and their Inhibitors, Part B, Volume 50 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics surrounding enzymes.