Mass Spectrometry in Drug Discovery, Rossi, David T.

Автор: John Greaves
Название: Mass Spectrometry for the Novice
ISBN: 1420094181 ISBN-13(EAN): 9781420094183
Издательство: Taylor&Francis
Рейтинг:
Цена: 80630.00 T
Наличие на складе: Нет в наличии.
Описание:

With usage of mass spectrometry continually expanding, an increasing number of scientists, technicians, students, and physicians are coming into contact with this valuable technique. Mass spectrometry has many uses, both qualitative and quantitative, from analyzing simple gases to environmental contaminants, pharmaceuticals, and complex biopolymers. The extraordinary versatility can make mass spectrometers daunting to novices. Consequently, new users would benefit greatly from an understanding of the basic concepts as well as the processes that occur in these instruments. Mass Spectrometry for the Novice provides exactly that, with detailed, straightforward descriptions and clear illustrations of principles of operations and techniques.

The book begins with an overview that includes essential definitions and then provides information on the components of and the strategies used in the most common instruments. The authors discuss the methodologies available, classes of compounds analyzed, and the types of data that can be generated. A group of representative applications from published articles is summarized, demonstrating the diversity of mass spectrometry. The authors also condense the essentials of the topic into one invaluable chapter that provides a set of concise take-home messages on all aspects of mass spectrometry. The final section provides a collection of resources including books, reviews, and useful websites.

Using simple language, new color figures, clever cartoons, and assuming no prior knowledge, this book provides a readily understandable entr e to mass spectrometry. A CD-ROM with selected figures and cartoons is included.

Автор: Vladimir A. Krasnopolsky
Название: Spectroscopy and Photochemistry of Planetary Atmospheres and Ionospheres: Mars, Venus, Titan, Triton and Pluto
ISBN: 1107145260 ISBN-13(EAN): 9781107145269
Издательство: Cambridge Academ
Рейтинг:
Цена: 83430.00 T
Наличие на складе: Поставка под заказ.
Описание: This book provides a detailed overview of the fundamental principles and methods of spectroscopy and photochemical modeling for studying the chemical composition of planetary atmospheres and ionospheres. With detailed reviews of Mars, Venus, Titan, Triton and Pluto, it is a valuable reference for graduate students, researchers and planetary scientists.

Автор: Uttam Garg
Название: Clinical Applications of Mass Spectrometry in Biomolecular Analysis
ISBN: 1493950096 ISBN-13(EAN): 9781493950096
Издательство: Springer
Рейтинг:
Цена: 102480.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

1. Mass Spectrometry in Clinical Laboratory: Applications in Biomolecular Analysis
Uttam Garg and Y. Victoria Zhang

2. Quantification of Free Carnitine and Acylcarnitines in Plasma or Serum Using HPLC/MS/MS
David Scott, Bryce Heese, and Uttam Garg

3. Quantification of Arginine and its Methylated Derivatives in Plasma by High Performance Liquid Chromatography Tandem Mass Spectrometry (LC-MS/MS)
Faye B. Vicente, Gina Vespa, Alan Miller, and Shannon Haymond

4. Quantitation of Albumin in Urine by Liquid Chromatography Tandem Mass Spectrometry
Hemamalini Ketha and Ravinder J. Singh

5. Quantitation of Aldosterone in Serum or Plasma Using Liquid Chromatography -Tandem Mass Spectrometry (LC-MS/MS)
J. Grace Van Der Gugten and Daniel T. Holmes

6. Quantification of Five Clinically Important Amino Acids by HPLC-Triple TOF(TM) 5600 Based on Pre-Column Double Derivatization Method
Shuang Deng, David Scott, and Uttam Garg

7. Sensitive, Simple, and Robust Nano Liquid Chromatography-Mass Spectrometry Method for Amyloid

22. Quantitation of Parathyroid Hormone in Serum or Plasma by Liquid Chromatography Tandem Mass Spectrom

Название: High-throughput mass spectrometry in drug discovery
ISBN: 1119678439 ISBN-13(EAN): 9781119678434
Издательство: Wiley
Рейтинг:
Цена: 179520.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Автор: Korfmacher
Название: Mass Spectrometry for Drug Discovery and Drug Deve lopment
ISBN: 047094238X ISBN-13(EAN): 9780470942383
Издательство: Wiley
Рейтинг:
Цена: 120330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Автор: Frigerio
Название: Mass Spectrometry in Drug Metabolism
ISBN: 1461341531 ISBN-13(EAN): 9781461341536
Издательство: Springer
Рейтинг:
Цена: 81050.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: When a dose of drug is administered, three main phases of drug action may be distingushed.

Автор: Bolgar Mark S.
Название: Mass Spectrometry in Biopharmaceutical and Emerging Drug Modalities
ISBN: 1782629750 ISBN-13(EAN): 9781782629757
Издательство: Royal Society of Chemistry
Рейтинг:
Цена: 223870.00 T
Наличие на складе: Невозможна поставка.
Описание: The focus of this book is on the use of mass spectrometry (MS) for the assessment of alternative modes of drug efficacy and inclusion of information on the use of MS in the development of protein biosimilars.

Название: Using Mass Spectrometry for Drug Metabolism Studies
ISBN: 0367384957 ISBN-13(EAN): 9780367384951
Издательство: Taylor&Francis
Рейтинг:
Цена: 65320.00 T
Наличие на складе: Нет в наличии.
Описание:

The first edition of this now classic work helped to establish mass spectrometry as the premier tool for drug metabolism studies. Completely rewritten from start to finish, Using Mass Spectrometry for Drug Metabolism Studies, Second Edition brings medicinal chemists and mass spectrometry professionals up to speed with the rapid advances in the field, the emergence of cutting-edge approaches, and ways to meet steadily increasing vendor demands. Written by international scientists who are experts in their respective disciplines, this state-of-the-art reference effectively encapsulates current mass spectrometry best practices.

The stand-alone chapters cover various topics - from metabolite identification to fast chromatography with UPLC - and in a style that is understandable to experts and field newcomers alike. The second edition of this bestseller includes coverage of new instrumentation and software as well as a wealth of updated information on the latest findings surrounding biomarkers and metabolomics and new chapters on both UPLC and DESI/DART.

With more than 180 illustrations and an eight-page color insert, this valuable reference explores multiple modern mass spectrometry techniques and strategies. It includes an excellent overview of the entire drug discovery process plus the latest developments on how mass spectrometry is used to support this endeavor.

Автор: Korfmacher, Walter A.
Название: Using Mass Spectrometry for Drug Metabolism Studies
ISBN: 1420092200 ISBN-13(EAN): 9781420092202
Издательство: Taylor&Francis
Рейтинг:
Цена: 224570.00 T
Наличие на складе: Нет в наличии.

Автор: Kay
Название: Chemical Analysis of Non-antimicrobial Veterinary Drug Residues in Food
ISBN: 1118695070 ISBN-13(EAN): 9781118695074
Издательство: Wiley
Рейтинг:
Цена: 178410.00 T
Наличие на складе: Поставка под заказ.

Автор: Matthew Jenner
Название: Using Mass Spectrometry for Biochemical Studies on Enzymatic Domains from Polyketide Synthases
ISBN: 3319327224 ISBN-13(EAN): 9783319327228
Издательство: Springer
Рейтинг:
Цена: 95770.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction.- Materials and Methods.- Substrate Specificity of Ketosynthase Domains Part I: β-Branched Acyl Chains.- Substrate Specificity of Ketosynthase Domains Part II: Amino Acid-Containing Acyl Chains.- Synthesis of Acyl-Acyl Carrier Proteins and their use in Studying Polyketide Synthase Enzymology.- Substrate Specificity of Ketosynthase Domains Part III: Elongation-Based Substrate Specificity.

Автор: Hoffmann, Edmond De Stroobant, Vincent
Название: Mass spectrometry
ISBN: 0470033118 ISBN-13(EAN): 9780470033111
Издательство: Wiley
Рейтинг:
Цена: 53800.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The latest edition of a highly successful textbook, Mass Spectrometry, Third Edition provides students with a complete overview of the principles, theories and key applications of modern mass spectrometry. All instrumental aspects of mass spectrometry are clearly and concisely described: sources, analyzers and detectors.