Protein Microarrays for Disease Analysis: Methods and Protocols, Barderas Rodrigo, Labaer Joshua, Srivastava Sanjeeva

Автор: Kohane, Isaac S.
Название: Microarrays for Integrative Genomics
ISBN: 026211271X ISBN-13(EAN): 9780262112710
Издательство: MIT Press
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Цена: 16140.00 T
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Описание: Functional genomics - the decontruction of the genome to determine the biological function of genes and gene interactions - is a growing area of biology. This volume provides a systematic introduction to the use of DNA microarrays as an investigative tool for functional genomics.

Автор: Navid Rabiee and Michael R Hamblin
Название: Protein and Peptide-based Microarrays for Multiplex Detection
ISBN: 075033665X ISBN-13(EAN): 9780750336659
Издательство: INGRAM PUBLISHER SERVICES UK
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Цена: 168960.00 T
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Описание: Doreen Carwithen and her husband William Alwyn were two of the most versatile composers working in Britain in the mid- to late-20th century. Between them they scored more than 100 films, as well as music for the concert hall, including the scores for Odd Man Out Alwyn and Boys in Brown Carwithen. Daniel Grimwoods recording is a wonderful introduction to the couples extensive catalogues of piano music, containing Carwithens taut, neoclassical Sonatina and Alwyns 12 Preludes and Grieg-inspired Fantasy Waltzes. This is warm, lyrical music which quietly pushes boundaries while always attractive and well-written for the

Автор: Khademhosseini Ali, Suh Kahp-Yang, Zourob Mohammed
Название: Biological Microarrays: Methods and Protocols
ISBN: 1493957635 ISBN-13(EAN): 9781493957637
Издательство: Springer
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Цена: 121110.00 T
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Описание: Recent developments in microarray technology have changed the landscape of biology and biomedical research, and they have revolutionized RNA and DNA research. In Biological Microarrays: Methods and Protocols, expert researchers explore exciting new developments in the field, providing a comprehensive approach to biological microarrays that conveys not only the state-of-the-art fundamentals, but also includes applications of the most innovative methods. Chapters address both the application of biological microarrays, including DNA/RNA, apatmer, proteins, tissues, oligonucleotides, carbohydrates, biomaterials, cells, bacteria, and virus microarrays, and also explore the different techniques used for generating microarray platforms. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Wide-ranging and revolutionary, Biological Microarrays: Methods and Protocols serves as a primary source for academics, practitioners, and professionals in related fields, including biologists, biotechnologists, biochemists, analytical chemists, and biomedical, physical, and microsystems engineers, to name a few, appealing to all of those interested in the present and future state of biological microarray research.

Автор: Uttamchandani Mahesh, Yao Shao Q.
Название: Small Molecule Microarrays: Methods and Protocols
ISBN: 1493982427 ISBN-13(EAN): 9781493982424
Издательство: Springer
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Цена: 88500.00 T
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Описание:

The Expanding World of Small Molecule Microarrays.- Novel Substrates for Microarrays.- Fabrication of Bio-function-preserved Saccharide Microarray Chips with Cyanuric Chloride as a Rotatable Linker.- Fabrication of Carbohydrate Microarrays by Boronate Formation.- Clickable Polymeric Coating for Glycan Microarrays.- A Versatile Microarray Immobilization Strategy Based on a Biorthogonal Reaction between Tetrazine and Trans-Cyclooctene.- Label-Free Sensing on Microarrays.- Optical Microscopy for Detecting Binding on Small Molecule Microarrays.- Array-on-array Strategy For Activity-based Enzyme Profiling.- Protein-Protein Interaction Inhibitors of BRCA1 Discovered Using Small Molecule Microarrays.- Discovery of RNA Binding Small Molecules Using Small Molecule Microarrays.- Profiling Phosphopeptide-binding Domain Recognition Specificity using Peptide Microarrays.- Validation Procedure for Multiplex Antibiotic Immunoassays Using Flow-based Chemiluminescence Microarrays.- Large-scale Interaction Profiling of Protein Domains through Proteomic Peptide-PhageDisplay using Custom Peptidomes.- Synthetic Glycan Microarrays.- Screening Mammalian Cells on a Hydrogel- Functionalized Small Molecule Microarray.

Автор: Draghici, Sorin (wayne State University, Detroit, Michigan, Usa)
Название: Statistics and data analysis for microarrays using r and bioconductor
ISBN: 1439809755 ISBN-13(EAN): 9781439809754
Издательство: Taylor&Francis
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Цена: 100030.00 T
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Описание: Richly illustrated in color, this bestselling text provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms, and cryptic notations, the text takes a hands-on, example-based approach that explains the basics of R and micr

Автор: Ulrike Korf
Название: Protein Microarrays
ISBN: 1493957767 ISBN-13(EAN): 9781493957767
Издательство: Springer
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Цена: 135090.00 T
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Описание: Protein microarrays can overcome the sensitivity and sample limitations of functional proteomics. This volume is an exhaustive and up-to-date presentation of robust protein microarray strategies that furthers the advance of this powerful laboratory technology.

Автор: Wang, Sun-Chong , Petronis, Art
Название: DNA Methylation Microarrays
ISBN: 0367387409 ISBN-13(EAN): 9780367387402
Издательство: Taylor&Francis
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Цена: 65320.00 T
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Providing an interface between dry-bench bioinformaticians and wet-lab biologists, DNA Methylation Microarrays: Experimental Design and Statistical Analysis presents the statistical methods and tools to analyze high-throughput epigenomic data, in particular, DNA methylation microarray data. Since these microarrays share the same underlying principles as gene expression microarrays, many of the analyses in the text also apply to microarray-based gene expression and histone modification (ChIP-on-chip) studies.

After introducing basic statistics, the book describes wet-bench technologies that produce the data for analysis and explains how to preprocess the data to remove systematic artifacts resulting from measurement imperfections. It then explores differential methylation and genomic tiling arrays. Focusing on exploratory data analysis, the next several chapters show how cluster and network analyses can link the functions and roles of unannotated DNA elements with known ones. The book concludes by surveying the open source software (R and Bioconductor), public databases, and other online resources available for microarray research.

Requiring only limited knowledge of statistics and programming, this book helps readers gain a solid understanding of the methodological foundations of DNA microarray analysis.

Автор: Yann Chevolot
Название: Carbohydrate Microarrays
ISBN: 1493958666 ISBN-13(EAN): 9781493958665
Издательство: Springer
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Цена: 107130.00 T
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Описание: Carbohydrate microarrays emerged as a key technology for the deciphering of the glycospace by providing a multiplex technology where tens to hundreds of carbohydrates/protein interactions can be probed in parallel. Carbohydrate Microarrays: Methods and Protocols aims to give the reader the theoretical and experimental clues necessary for the fabrication and implementation of carbohydrate microarrays. This requires three essential steps: 1) to obtain the carbohydrate probes (monosacharides, oligosacchrides, polysacchairdes, glycoconjugates or glycoclusters), 2) to immobilize these probes, and 3) to implement the protocols for biological/biochemical interaction with the desired target. This volume gives an overview of carbohydrate microarray and carbohydrate chemistry and illustrates different detection techniques and their applications. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Carbohydrate Microarrays: Methods and Protocols compiles a catalogue of protocols on carbohydrate microarrays to span the needs of researchers around the globe.