Statistics and data analysis for microarrays using r and bioconductor, Draghici, Sorin (wayne State University, Detroit, Michigan, Usa)

Автор: B.R. Jordan
Название: DNA Microarrays: Gene Expression Applications
ISBN: 3540415084 ISBN-13(EAN): 9783540415084
Издательство: Springer
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Цена: 71730.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: A practical manual on expression measurement using DNA arrays. It covers various methods (from nylon macroarrays to oligonucleotide chips) and includes detailed protocols. It also covers software, data mining procedures and probable future developments.

Автор: James V Rogers
Название: Microarrays: Principles, Applications & Technologies
ISBN: 1629486698 ISBN-13(EAN): 9781629486697
Издательство: Nova Science
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Цена: 205910.00 T
Наличие на складе: Невозможна поставка.
Описание: The sequencing of the human genome was a pivotal event in science that opened the door to exploring the structure and function of genes and their regulation. The activation or suppression of transcribed genes is critical to the orchestration of everyday biological processes at the cellular, tissue, and physiological levels. The rapid advance of science and technology has yielded the development of the microarray technique, which has propelled a much deeper understanding of the genome. By combining these technological advances in microarrays with statistical and bioinformatics software, investigators are now able to perform scientific investigations geared towards answering unique biological problems that encompass many fields of research from genetics and evolution to molecular medicine, health, and disease. This book provides an overview of the use and application of microarrays throughout the life sciences to address diverse complex biological questions. In this collection, authors present information on using microarrays to unlock molecular mechanisms and gene expression patterns associated with research areas ranging from biodefense, pathological changes, and monitoring antimicrobial resistance genes to diagnostics, marine biodiversity, and dermal toxicology.

Автор: Kilian Dill; Robin Liu; Piotr Grodzinsky
Название: Microarrays
ISBN: 1441924906 ISBN-13(EAN): 9781441924902
Издательство: Springer
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Цена: 139310.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Combinatorial chemistry is used to find materials that form sensor microarrays. This book discusses the fundamentals, and then proceeds to the many applications of microarrays, from measuring gene expression (DNA microarrays) to protein-protein interactions.

Автор: Wang, Sun-Chong , Petronis, Art
Название: DNA Methylation Microarrays
ISBN: 0367387409 ISBN-13(EAN): 9780367387402
Издательство: Taylor&Francis
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Цена: 65320.00 T
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Описание:

Providing an interface between dry-bench bioinformaticians and wet-lab biologists, DNA Methylation Microarrays: Experimental Design and Statistical Analysis presents the statistical methods and tools to analyze high-throughput epigenomic data, in particular, DNA methylation microarray data. Since these microarrays share the same underlying principles as gene expression microarrays, many of the analyses in the text also apply to microarray-based gene expression and histone modification (ChIP-on-chip) studies.

After introducing basic statistics, the book describes wet-bench technologies that produce the data for analysis and explains how to preprocess the data to remove systematic artifacts resulting from measurement imperfections. It then explores differential methylation and genomic tiling arrays. Focusing on exploratory data analysis, the next several chapters show how cluster and network analyses can link the functions and roles of unannotated DNA elements with known ones. The book concludes by surveying the open source software (R and Bioconductor), public databases, and other online resources available for microarray research.

Requiring only limited knowledge of statistics and programming, this book helps readers gain a solid understanding of the methodological foundations of DNA microarray analysis.

Автор: Hans-Joachim M??ller
Название: Microarrays,
ISBN: 0120885433 ISBN-13(EAN): 9780120885435
Издательство: Elsevier Science
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Цена: 50060.00 T
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Описание: "Microarrays" is an invaluable laboratory manual for anyone conducting experiments in the field of molecular biology or medical biochemistry who needs to understand and use microarray technologies. These technologies are especially appropriate in genome analysis, diagnostics, and studies involving differential gene expression. Providing straightforward explanations, the authors demonstrate proven methods for biochip application and an overview of presently available instruments, biochips, and software. Chapters cover the different requirements for DNA and protein chips, as well as spotters and scanners. This book also covers high throughput screening, patent research, and the minimum requirements for setting up or expanding a microarray laboratory.