Biological Microarrays: Methods and Protocols, Khademhosseini Ali, Suh Kahp-Yang, Zourob Mohammed

Автор: Jang B. Rampal
Название: Microarrays
ISBN: 1617378526 ISBN-13(EAN): 9781617378522
Издательство: Springer
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Цена: 144410.00 T
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Описание: This second part in the two-volume work Microarrays details applications and data analysis. It includes insight into non-mammalian vertebrate systems, processes and protocols for high quality glass-based microarrays.

Автор: Jang B. Rampal
Название: Microarrays
ISBN: 1617376639 ISBN-13(EAN): 9781617376634
Издательство: Springer
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Цена: 153720.00 T
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Описание: These two volumes present information in designing and fabricating arrays and binding studies with biological analytes. This is done while providing the reader with a broad description of microarray technology tools and their potential applications.

Автор: James V Rogers
Название: Microarrays: Principles, Applications & Technologies
ISBN: 1629486698 ISBN-13(EAN): 9781629486697
Издательство: Nova Science
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Цена: 205910.00 T
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Описание: The sequencing of the human genome was a pivotal event in science that opened the door to exploring the structure and function of genes and their regulation. The activation or suppression of transcribed genes is critical to the orchestration of everyday biological processes at the cellular, tissue, and physiological levels. The rapid advance of science and technology has yielded the development of the microarray technique, which has propelled a much deeper understanding of the genome. By combining these technological advances in microarrays with statistical and bioinformatics software, investigators are now able to perform scientific investigations geared towards answering unique biological problems that encompass many fields of research from genetics and evolution to molecular medicine, health, and disease. This book provides an overview of the use and application of microarrays throughout the life sciences to address diverse complex biological questions. In this collection, authors present information on using microarrays to unlock molecular mechanisms and gene expression patterns associated with research areas ranging from biodefense, pathological changes, and monitoring antimicrobial resistance genes to diagnostics, marine biodiversity, and dermal toxicology.

Автор: Ulrike Korf
Название: Protein Microarrays
ISBN: 1493957767 ISBN-13(EAN): 9781493957767
Издательство: Springer
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Цена: 135090.00 T
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Описание: Protein microarrays can overcome the sensitivity and sample limitations of functional proteomics. This volume is an exhaustive and up-to-date presentation of robust protein microarray strategies that furthers the advance of this powerful laboratory technology.

Автор: Mahesh Uttamchandani; Shao Q. Yao
Название: Small Molecule Microarrays
ISBN: 1493958151 ISBN-13(EAN): 9781493958153
Издательство: Springer
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Цена: 158380.00 T
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Описание: Small molecule microarrays (SMM) were introduced just a decade ago in 1999 and, within a short space of time, have already established themselves as a vibrant, next generation platform for high-throughput screening. Small Molecule Microarrays: Methods and Protocols showcases a collection of contributions guiding researchers toward ways in which small molecule microarray technology may be deployed for multiplexed screening and profiling. Organized by the categories of small molecules presented on the microarrays, this detailed volume describes in-depth techniques for chemical libraries, peptide libraries, and carbohydrate microarrays. Written in the highly successful Methods in Molecular Biology™ series, chapters contain brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, vital tips on troubleshooting this often difficult technology, and advice on avoiding known pitfalls. Authoritative and cutting-edge, Small Molecule Microarrays: Methods and Protocols provides meticulous depictions of key hands-on experience and seeks to inspire a future generation of microarray practitioners to take this significant technology forward.

Автор: Ella Palmer
Название: Cell-Based Microarrays
ISBN: 1493905937 ISBN-13(EAN): 9781493905935
Издательство: Springer
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Цена: 60940.00 T
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Описание: This book is a review on the evolution of cell-based microarrays and an update to the author`s earlier book Methods in Molecular Biology: Cell-Based Microarrays. Since their development in 2001, cell-based microarrays have advanced significantly to include expression arrays, short interfering RNA arrays and antibody arrays.

Автор: Bertrand Jordan
Название: Microarrays in Diagnostics and Biomarker Development
ISBN: 3642439764 ISBN-13(EAN): 9783642439766
Издательство: Springer
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Цена: 148010.00 T
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Описание: This book provides a comprehensive overview of microarrays in diagnostics and biomarker development, covering DNA, peptide, protein and tissue arrays. It emphasizes entities in actual clinical use as well as recent developments, such as aptamer arrays.

Автор: Yann Chevolot
Название: Carbohydrate Microarrays
ISBN: 1493958666 ISBN-13(EAN): 9781493958665
Издательство: Springer
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Цена: 107130.00 T
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Описание: Carbohydrate microarrays emerged as a key technology for the deciphering of the glycospace by providing a multiplex technology where tens to hundreds of carbohydrates/protein interactions can be probed in parallel. Carbohydrate Microarrays: Methods and Protocols aims to give the reader the theoretical and experimental clues necessary for the fabrication and implementation of carbohydrate microarrays. This requires three essential steps: 1) to obtain the carbohydrate probes (monosacharides, oligosacchrides, polysacchairdes, glycoconjugates or glycoclusters), 2) to immobilize these probes, and 3) to implement the protocols for biological/biochemical interaction with the desired target. This volume gives an overview of carbohydrate microarray and carbohydrate chemistry and illustrates different detection techniques and their applications. Written in the successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and easily accessible, Carbohydrate Microarrays: Methods and Protocols compiles a catalogue of protocols on carbohydrate microarrays to span the needs of researchers around the globe.