Clinical Pharmacokinetics, John E. Murphy (author)

Автор: Kar A
Название: Essentials Of Biopharmaceutics And Pharmacokinetics For Bpharm Mpharm And Research Scholars 2Ed
ISBN: 9388327535 ISBN-13(EAN): 9789388327534
Издательство: CBS India
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Цена: 24140.00 T
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Описание: A comprehensive textbook for learning and teaching the fundamentals of biopharmaceutics along with specific focus on pharmacokinetics for BPharm and MPharm students.

Автор: Robin Southwood, Virginia H. Fleming, Gary Huckaby
Название: Concepts in Clinical Pharmacokinetics
ISBN: 1585285919 ISBN-13(EAN): 9781585285914
Издательство: Mare Nostrum (Eurospan)
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Цена: 112860.00 T
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Описание: Understanding the science of pharmacokinetics is a challenge for many pharmacy students and practitioners. Concepts in Clinical Pharmacokinetics, now in its 7th edition, has helped thousands by simplifying this essential, but complex, subject to reflect current practice. The 7th edition has been revised by Robin Southwood, PharmD, BC-ADM, CDE; Virginia H. Fleming, PharmD, BCPS; and Gary Huckaby, PharmD; all experts in clinical pharmacy education. Together, they have updated and expanded the text to include the latest information and insights on concepts through extensive use of correlates, figures, and review questions. Inside you will find:15 easy-to-follow lessons, perfect for a semesterPractice quizzes to help chart progressEnhanced discussion of hemodialysisA phenytoin “cheat sheet” to help you through the calculations mazeNew vancomycin cases based on higher desired vancomycin levels and trough-only dose estimationsExpanded information on modified diet in renal disease formula versus Cockcroft-Gault formula methodsFactors to consider when choosing a dosing/body weight for various equationsUpdated clinical correlates, discussion points, references, and questions/answersConcepts in Clinical Pharmacokinetics is the fundamental reference for learning the basic, foundational pharmacokinetics concepts and how to apply them in clinical practice.

Автор: Andrea Angelini
Название: Voriconazole: Pharmacokinetics, Role in Therapeutic Drug Monitoring & Clinical Outcomes
ISBN: 163463313X ISBN-13(EAN): 9781634633130
Издательство: Nova Science
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Цена: 224920.00 T
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Описание: In the last twenty years, the incidence of invasive fungal infections (IFI) has risen dramatically due to the prolongation of survival of patients with multiple risk factors for fungal infections and due to the increase of infection associated with travel. Moreover IFI in infants admitted to the neonatal intensive care unit are common and often fatal. Amphotericin B was for more than 40 years the gold standard for almost all IFI, but toxicity and resistance, especially of new and emerging pathogens remained important issues. Fluconazole and itraconazole have also the same disadvantage of resistance. After a long period of relative inactivity in the introduction of new antifungals, more recently a few new drugs of already existing classes have been introduced as important agents in the treatment and prevention of IFI. These represent small or large advantages and differences compared with existing available alternative therapy for deep and systemic mycoses. Voriconazole is a second-generation triazole antifungal drug, often prescribed as first-line therapy for candidemia, in non-neutropenic hosts, for invasive pulmonary aspergillosis and as prophylaxis of many systemic mycoses. In-vitro and in-vivo studies showed that voriconazole has broad-spectrum activity against most Candida species, Aspergillus species, fusariosis or scedosporiosis. Voriconazole has non-linear pharmacokinetics and, as substrate and inhibitor of cytochrome P450, it undergoes extensive hepatic metabolism that depends on age, genetic factors, and interactions with other drugs, which may lead to enhanced toxicity of the concomitant medication(s) or ineffective antifungal treatment. This book presents an update on voriconazole research, particularly its pharmacology, microbiology, toxicology, and clinical outcomes in order to optimize its use in daily clinical practice.

Автор: Bauer
Название: Handbook of clinical pharmacokinetics
ISBN: 007142542X ISBN-13(EAN): 9780071425421
Издательство: McGraw-Hill
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Цена: 42310.00 T
Наличие на складе: Поставка под заказ.
Описание: Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. It also features calculation methods, algorithms for choosing the best calculation method, and case studies.

Автор: Ronald Carman
Название: Zoledronic Acid: Clinical Uses, Therapeutic Effects and Pharmacokinetics
ISBN: 1633215253 ISBN-13(EAN): 9781633215252
Издательство: Nova Science
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Цена: 257650.00 T
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Описание: An Introduction Third Edition 2015. This book describes the principles of the blast furnace process and especially the control of the process. As a starting point, the blast furnace is seen as a simple iron ore smelter, while gradually the physical, chemical and metallurgical background of the blast furnace process is clarified. The book focuses on the control of the blast furnace process with respect to thermal control, gas flow control and casthouse operation. In this book, all essential process details are described and a special focus is on optimization of coal injection. The optimization of the blast furnace process is not only

Автор: Juan M Coello, Yolanda D Sabres
Название: Vincristine: Clinical Uses, Pharmacokinetics & Impacts on Health
ISBN: 1628088869 ISBN-13(EAN): 9781628088861
Издательство: Nova Science
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Цена: 103480.00 T
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Описание: The purpose of this work is to improve service learning research and practice through strengthening its theoretical base. The authors bring theoretical perspectives from a wide variety of disciplines to bear as they critically review past research, describe assessment methods and instruments, develop future research agendas, and consider implications of theory-based research for enhanced practice.

Автор: Michael W. Jann; Scott R. Penzak; Lawrence J. Cohe
Название: Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents
ISBN: 3319802348 ISBN-13(EAN): 9783319802343
Издательство: Springer
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Цена: 111790.00 T
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Описание: Thisbook is a comprehensive resource on psychotropic medications, detailing thelatest methods for defining their characteristics, their use in differentpatient populations, and drug-drug interactions; an important collection ofinformation forclinicians, students, researchers, and members of thepharmaceutical industry alike.Thefirst section provides the foundational principles of these drugs. Mathematicalmodeling of parameters that affect their entryto,and exit from, the centralnervous system (CNS) compartment are presented on an individual basis and thenapplied to target populations with specific disease states. Methods andcharacteristics that inform the transfer of these drugs from the laboratorybench to use in patient care are discussed, including imaging techniques,genetics and physiological barriers, such as the blood-brain barrier. The secondsection describes the characteristics of specific agents,nominally arrangedintodifferent therapeutic categories and with reference crossover use indifferent disease states. The pharmacologic characteristics of different drugformulations are explored in the context of their ability to improve patientadherence. The third section focuses on drug-drug interactions.Psychotropic medicationsfrom different categories are frequently prescribed together,or alongsidemedications used to treat comorbid conditions, and the information provided isdirectly relevant to the clinic, as a result.Theclinical application of pharmacokinetics and pharmacodynamics of CNS agents hasmade significant progress over the past 50 years and new information is reportedby numerous publications in psychiatry, neurology, and pharmacology.Ourunderstanding of the interrelationship between these medications, receptors,drug transporters, as well as techniques for measurement and monitoring theirinteractions,isfrequently updated. However, with information presented on ahost of different platforms, and in different formats, obtaining the fullpicture can be difficult. This title aims to collate this information into asingle source that can be easily interpreted and applied towards patient careby the clinical practitioner, and act as a reference for all others who have aninterest in psychopharmacological agents.

Автор: Bonate Peter, Howard Danny
Название: Pharmacokinetics in Drug Development / Clinical Study Design and Analysis (Volume 1)
ISBN: 0971176744 ISBN-13(EAN): 9780971176744
Издательство: Springer
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Цена: 204970.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.

Автор: John E. Murphy
Название: Clinical Pharmacokinetics
ISBN: 1585286591 ISBN-13(EAN): 9781585286591
Издательство: Mare Nostrum (Eurospan)
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Цена: 94250.00 T
Наличие на складе: Нет в наличии.

Автор: Bauer, Larry A.
Название: Applied clinical pharmacokinetics
ISBN: 0071476288 ISBN-13(EAN): 9780071476287
Издательство: McGraw-Hill
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Цена: 51470.00 T
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Описание: Features coverage of drug dosing and monitoring. This book focuses on the standardized techniques and approaches to patient-specific dosing. It also contains sections on dosing strategies in the chapters and a chapter on sirolimus.

Автор: Derendorf
Название: Rowland and Tozer`s Clinical Pharmacokinetics and Pharmacodynamics:
ISBN: 1496385047 ISBN-13(EAN): 9781496385048
Издательство: Lippincott Williams & Wilkins
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Цена: 97240.00 T
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Описание: Updated with the latest clinical advances, Rowland and Tozer's Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition, explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.

• Key updates reflect advances in PK/PD as related to clinical decision making and drug research and development.
• An emphasis on the clinical relevance of drugs makes the book especially applicable to pharmacy students preparing for a career in clinical practice.
• Hundreds of graphs and tables provide visual representations of key pharmacokinetic/pharmacodynamic principles and effects.
• More than 200 carefully written study questions, with answers and in-depth explanations, help readers enhance their conceptual understanding and learn and retain key information.
• New and updated examples connect chapter content to real-world settings.
• Interactive online simulations give students practice using different pharmacokinetic/pharmacodynamic models and parameters.

Автор: Rosenbaum Sara E.
Название: Basic Pharmacokinetics and Pharmacodynamics
ISBN: 1119143152 ISBN-13(EAN): 9781119143154
Издательство: Wiley
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Цена: 72810.00 T
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Описание: This book provides a comprehensive foundation for the contemporary application of pharmacokinetics and pharmacodynamics. The second edition updates and strengthens existing chapters and adds new topics to address current needs including physiologically based pharmacokinetic modeling, pharmacogenomics and predicting drug-drug interactions.