Rowland and Tozer`s Clinical Pharmacokinetics and Pharmacodynamics:, Derendorf

Автор: Rowland
Название: Clinical Pharmacokinetics and Pharmacodynamics, 4e
ISBN: 0781750091 ISBN-13(EAN): 9780781750097
Издательство: Lippincott Williams & Wilkins
Цена: 80080 T
Наличие на складе: Невозможна поставка.
Описание: Reflects the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This title also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs.

Автор: Winter
Название: Basic Clinical Pharmacokinetics
ISBN: 0781741475 ISBN-13(EAN): 9780781741477
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 41750.00 T
Наличие на складе: Невозможна поставка.
Описание: Basic Clinical Pharmacokinetics was designed to simplify pharmacokinetics to help busy practitioners understand and visualize basic principles. An easy-to-read, case-study format has made the text a favorite among clinical professors, students, and practitioners. The text provides an introduction to the principles of monitoring drug therapy for those involved in the interpretation of drug levels in a patient care setting. Part One provides a basic review of pharmacokinetic principles. Extensive explanations, graphic illustrations, and detailed algorithms teach the principles of bioavailability, volume of distribution, clearance, elimination rate constant, and half-life. Part Two explains the clinical applications of these principles. Solutions to problems commonly encountered in the practice setting are discussed for specific drugs. Appendices provide commonly used equations and a glossary of pharmacokinetic terms and abbreviations. New to this edition are chapters on tricyclic antidepressants and cyclosporine, an expanded chapter on dialysis, and updated information on choosing equations and interpreting plasma drug concentrations.

Автор: Rowland
Название: Clinical Pharmacokinetics and Pharmacodynamics, 4e
ISBN: 0781750091 ISBN-13(EAN): 9780781750097
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 80080.00 T
Наличие на складе: Невозможна поставка.
Описание: Reflects the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This title also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs.

Автор: Rescigno Aldo
Название: Foundations of Pharmacokinetics
ISBN: 0306477041 ISBN-13(EAN): 9780306477041
Издательство: Springer
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Цена: 174150.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book is divided into two parts; in the first part the principles and the methods of pharmacokinetics are described in detail, while in the second the main pharmacokinetic parameters are described, giving for each of them the definition, the principal properties, and the methods of determination. An appendix contains the important mathematical instruments used in the main part of the book, namely the operational calculus and the convolution integral. In the second part there is a careful distinction among pharmacokinetic parameters, i.e., parameters that represent a true pharmacokinetic property, model parameters, i.e., parameters that represent a property of a specific model, and incidental parameters, i.e., parameters that represent only the result of a particular experiment. Special care is taken to distinguish between the definition of a parameter, and the properties that derive from that definition; a considerable emphasis is also given to the fact that each method for the determination of a parameter is dependent on the specific model it is based on.

Автор: Gopal B. Saha
Название: Fundamentals of Nuclear Pharmacy
ISBN: 3319575791 ISBN-13(EAN): 9783319575797
Издательство: Springer
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Цена: 93160.00 T
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Описание: Currently an estimated 17 million nuclear medicine procedures are performed each year in the US and constantly evolving, as new radiopharmaceuticals and imaging techniques are introduced for better diagnosis and treatment of human diseases.

Автор: Michelle A. Rudek; Cindy H. Chau; William D. Figg;
Название: Handbook of Anticancer Pharmacokinetics and Pharmacodynamics
ISBN: 1493938983 ISBN-13(EAN): 9781493938988
Издательство: Springer
Рейтинг:
Цена: 232910.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. * Road map to anticancer drug development from discovery to NDA submission * Discussion of molecular targets and preclinical screening * Development and validation of bioanalytical methods * Chapters on clinical trial design and phase 0, I, II, III clinical trials * Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents * Review of the drug development process from both laboratory and clinical perspectives * New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development

Автор: Younggil Kwon
Название: Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for Industrial Scientists
ISBN: 147578693X ISBN-13(EAN): 9781475786934
Издательство: Springer
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Цена: 149060.00 T
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Описание: In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization.

Автор: Aldo Rescigno
Название: Foundations of Pharmacokinetics
ISBN: 1475787391 ISBN-13(EAN): 9781475787399
Издательство: Springer
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Цена: 149060.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book has its origin in my experience as a teacher of pharmacokinetics in many universities in four different continents. Chapters 13 to 17 show how different parameters of importance in pharmacokinetics can be exactly defined and measured.

Автор: Peter L. Bonate; Danny R. Howard
Название: Pharmacokinetics in Drug Development
ISBN: 1489977996 ISBN-13(EAN): 9781489977991
Издательство: Springer
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Цена: 186330.00 T
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Описание: The topics chosen for this volume were selected because they are some of the current development or technological issues facing drug development project teams. They regard the practical considerations for assessment of selected special development populations. For example, they include characterization of drug disposition in pregnant subjects, for measuring arrhythmic potential, for analysis tumor growth modeling, and for disease progression modeling. Practical considerations for metabolite safety testing, transporter assessments, Phase 0 testing, and development and execution of drug interaction programs reflect current regulatory topics meant to address enhancement of both safety assessment and early decision-making during new candidate selection. Important technologies like whole body autoradiography, digital imaging and dried blood spot sample collection methods are introduced, as both have begun to take a more visible role in pharmacokinetic departments throughout the industry.

Автор: John E. Murphy
Название: Basic & Applied Pharmacokinetics Self Assessment
ISBN: 1585284386 ISBN-13(EAN): 9781585284382
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 46200.00 T
Наличие на складе: Невозможна поставка.
Описание: To exercise the best possible judgment in patient care, medication plans should be selected for the maximum efficacy and safety for each individual patient. Be confident in your approach with ASHP`s Basic Applied Pharmacokinetics Self Assessment, a new resource which offers questions and exercises with answers and detailed solutions to help gauge your understanding.

Автор: Bauer
Название: Applied Clinical Pharmacokinetics
ISBN: 0071794581 ISBN-13(EAN): 9780071794589
Издательство: McGraw-Hill
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Цена: 84650.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Helps you learn the clinical application of pharmacokinetics. This book delivers clear and clinically relevant coverage of drug dosing and drug monitoring that no other text can match. It offers the standardized techniques and approaches to patient-specific dosing, and information on pharmacokinetically monitored drugs.