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Pharmacokinetics in Drug Development / Clinical Study Design and Analysis (Volume 1), Bonate Peter, Howard Danny


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Цена: 204970.00T
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Автор: Bonate Peter, Howard Danny
Название:  Pharmacokinetics in Drug Development / Clinical Study Design and Analysis (Volume 1)
ISBN: 9780971176744
Издательство: Springer
Классификация:
ISBN-10: 0971176744
Обложка/Формат: Hardback
Страницы: 628
Вес: 1.32 кг.
Дата издания: 2004
Язык: English
Издание: 2004 ed.
Иллюстрации: 74 tables, black and white; xii, 628 p.
Размер: 25.40 x 17.81 x 3.51
Читательская аудитория: Professional & vocational
Подзаголовок: Clinical study design and analysis (volume 1)
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.
Дополнительное описание: Илюстрации: 101
Круг читателей: Pharmaceutical science and biochemistry
Язык: eng
Оглавление: First-Time-in-Man Studies.- Drug-Drug Interactions.- Food Effect Studies.- Bioavailability and Bioequivalence Studies.- Mass Balance Studies.- Design, Conduct, and Analysis of Studies in Patients with Hepatic Impairment.- Design, Conduct, and Analysis of Studies in Patients with Renal Impairment.- Special Populations.- Non-compartmental Analysis.- Analysis of Urine Excretion Data.- Compartmental Models.- The Role of Metabolite Pharmacokinetics and Pharmacodynamics in Drug Development.- Average, Population, and Individual Bioequivalence.- Assessment of Dose Proportionality.- Analysis of Absorption Kinetic Data.- Interspecies Pharmacokinetic Scaling: Principles, Applications, and Limitations.- In Vitro Drug Metabolism Information in the Prediction of Human Pharmacokinetics.- Practical Deconvolution.- Population Pharmacokinetics: Applications in Industry.- Clinical Trial Simulation.- The Strategic Role and Application of Pharmacokinetic/Pharmacodynamic Modeling in Drug Development.- The Analysis of Clincal Safety Data in Phase I-II Pharmacokinetic Studies.



Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics

Автор: Alexander Vinks; Hartmut Derendorf; Johan Mouton (
Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics
ISBN: 0387756124 ISBN-13(EAN): 9780387756127
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Handbook of clinical pharmacokinetics

Автор: Bauer
Название: Handbook of clinical pharmacokinetics
ISBN: 007142542X ISBN-13(EAN): 9780071425421
Издательство: McGraw-Hill
Рейтинг:
Цена: 42310.00 T
Наличие на складе: Поставка под заказ.
Описание: Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. It also features calculation methods, algorithms for choosing the best calculation method, and case studies.

Introduction to Pharmacokinetics and Pharmacodynamics: The Quantitative Basis of Drug Therapy

Автор: Tozer
Название: Introduction to Pharmacokinetics and Pharmacodynamics: The Quantitative Basis of Drug Therapy
ISBN: 0781751497 ISBN-13(EAN): 9780781751490
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 49190.00 T
Наличие на складе: Поставка под заказ.
Описание: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.

Pharmacokinetics in Drug Development / Regulatory and Development Paradigms (Volume 2)

Автор: Bonate Peter, Howard Danny
Название: Pharmacokinetics in Drug Development / Regulatory and Development Paradigms (Volume 2)
ISBN: 0971176736 ISBN-13(EAN): 9780971176737
Издательство: Springer
Цена: 149030.00 T
Наличие на складе: Поставка под заказ.
Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.

Applied Clinical Pharmacokinetics

Автор: Bauer
Название: Applied Clinical Pharmacokinetics
ISBN: 0071794581 ISBN-13(EAN): 9780071794589
Издательство: McGraw-Hill
Рейтинг:
Цена: 84650.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Helps you learn the clinical application of pharmacokinetics. This book delivers clear and clinically relevant coverage of drug dosing and drug monitoring that no other text can match. It offers the standardized techniques and approaches to patient-specific dosing, and information on pharmacokinetically monitored drugs.

Applied Pharmacokinetics and Pharmacodynamics

Автор: Burton
Название: Applied Pharmacokinetics and Pharmacodynamics
ISBN: 0781744318 ISBN-13(EAN): 9780781744317
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 51480.00 T
Наличие на складе: Невозможна поставка.
Описание: "The definitive advanced-level clinical pharmacokinetics text is now in its Fourth Edition, with new emphasis on the relationship between pharmacokinetics and pharmacodynamics. Written by 70 leading researchers and practitioners, this book is a rigorous yet practical text on the application of pharmacokinetic methods, pharmacodynamic principles, and pharmacotherapeutic data for optimal, individualized drug therapy.

Applied clinical pharmacokinetics

Автор: Bauer, Larry A.
Название: Applied clinical pharmacokinetics
ISBN: 0071476288 ISBN-13(EAN): 9780071476287
Издательство: McGraw-Hill
Рейтинг:
Цена: 51470.00 T
Наличие на складе: Поставка под заказ.
Описание: Features coverage of drug dosing and monitoring. This book focuses on the standardized techniques and approaches to patient-specific dosing. It also contains sections on dosing strategies in the chapters and a chapter on sirolimus.

Appl. Clinical Pharmacokinetics.2001

Автор: Bauer
Название: Appl. Clinical Pharmacokinetics.2001
ISBN: 0838503888 ISBN-13(EAN): 9780838503881
Издательство: McGraw-Hill
Цена: 32020.00 T
Наличие на складе: Невозможна поставка.
Описание: Improving upon and updating the information and format of the leading competing clinical pharmacokinetic text, Dr. Bauer, a nationally recognized leader in the field of pharmacokinetics has conceived a text for today and tomorrow's pharmacy student and practitioner. The text emphasizes the practical aspects of drug dosing for agents that have serum concentrations commonly available from clinical laboratories. Filling a hole in our list between Shargel and Schumacher, this new book will focus on patient specific drug dosing, thereby emphasizing the standard clinical pharmacokinetic dosing techniques.

Basic Clinical Pharmacokinetics

Автор: Winter
Название: Basic Clinical Pharmacokinetics
ISBN: 0781741475 ISBN-13(EAN): 9780781741477
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 41750.00 T
Наличие на складе: Невозможна поставка.
Описание: Basic Clinical Pharmacokinetics was designed to simplify pharmacokinetics to help busy practitioners understand and visualize basic principles. An easy-to-read, case-study format has made the text a favorite among clinical professors, students, and practitioners. The text provides an introduction to the principles of monitoring drug therapy for those involved in the interpretation of drug levels in a patient care setting. Part One provides a basic review of pharmacokinetic principles. Extensive explanations, graphic illustrations, and detailed algorithms teach the principles of bioavailability, volume of distribution, clearance, elimination rate constant, and half-life. Part Two explains the clinical applications of these principles. Solutions to problems commonly encountered in the practice setting are discussed for specific drugs. Appendices provide commonly used equations and a glossary of pharmacokinetic terms and abbreviations. New to this edition are chapters on tricyclic antidepressants and cyclosporine, an expanded chapter on dialysis, and updated information on choosing equations and interpreting plasma drug concentrations.


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