Peptide Antibiotics Biosynthesis and Functions: Enzymatic Formation of Bioactive Peptidesand Related Compounds, Hans von Dohren, Horst Kleinkauf
Автор: Walsh Christopher T., Tang Yi Название: Natural Product Biosynthesis: Chemical Logic and Enzymatic Machinery ISBN: 1788010760 ISBN-13(EAN): 9781788010764 Издательство: Marston Book Services Рейтинг: Цена: 118790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This textbook describes the types of natural products, the biosynthetic pathways that enable the production of these molecules, and an update on the discovery of novel products in the post-genomic era.
Автор: Bradley Evans Название: Nonribosomal Peptide and Polyketide Biosynthesis ISBN: 1493933736 ISBN-13(EAN): 9781493933730 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This volume presents an overview of nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) structure and function. It then continues with methods for the analysis of these pathways including conventional enzymological assays, contemporary mass spectrometric analysis techniques, specialized molecular biological approaches applicable to NRPSs and PKSs, and small molecule analysis tools tailored to this very special class of natural products, and concludes by examining bioinformatics tools for the analysis of these enzymes, pathways, and molecules. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Authoritative and practical, Nonribosomal Peptide and Polyketide Biosynthesis: Methods and Protocols serves as a valuable reference for those experienced in studying NRPS and PKS enzymes, pathways, and natural products as well as a gateway for those just entering the field.
Автор: Bradley Evans Название: Nonribosomal Peptide and Polyketide Biosynthesis ISBN: 1493980343 ISBN-13(EAN): 9781493980345 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Part I: Background and Overview
1. Structural Biology of Nonribosomal Peptide Synthetases
Bradley R. Miller and Andrew M. Gulick
2. The Assembly Line Enzymology of Polyketide Biosynthesis
Marisa Till and Paul R. Race
Part II: In Vitro Methods
3. Measurement of Nonribosomal Peptide Synthetase Adenylation Domain Activity Using a Continuous Hydroxylamine Release Assay
Benjamin P. Duckworth, Daniel J. Wilson, and Courtney C. Aldrich
4. Affinity Purification Method for the Identification of Nonribosomal Peptide Biosynthetic Enzymes Using a Synthetic Probe for Adenylation Domains
Fumihiro Ishikawa and Hideaki Kakeya
5. Colorimetric Detection of the Adenylation Activity in Nonribosomal Peptide Synthetases
6. Facile Synthetic Access to Glycopeptide Antibiotic Precursor Peptides for the Investigation of Cytochrome P450 Action in Glycopeptide Antibiotic Biosynthesis
Clara Brieke, Veronika Kratzig, Madeleine Peschke, and Max J. Cryle
7. Reconstitution of Fungal Nonribosomal Peptide Synthetases in Yeast and In Vitro
Ralph A. Cacho and Yi Tang
8. The Continuing Development of E. coli as a Heterologous Host for Complex Natural Product Biosynthesis
Haoran Zhang, Lei Fang, Marcia S. Osburne, and Blaine A. Pfeifer
9. Screening for Expressed Non
ribosomal Peptide Synthetases and Polyketide Synthases Using LC‒MS/MS-Based Proteomics
Yunqiu Chen, Ryan A. McClure, and Neil L. Kelleher
10. Enhancing Nonribosomal Peptide Biosynthesis in Filamentous Fungi
Alexandra A. Soukup, Nancy P. Keller, and Philipp Wiemann
11. In Situ Analysis of Bacterial Lipopeptide Antibiotics by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging
Delphine Debois, Marc Ongena, Hйlиne Cawoy, and Edwin De Pauw
13. Annotating and Interpreting Linear and Cyclic Peptide Tandem Mass Spectra
14. Bioinformatics Tools for the Discovery of New Nonribosomal Peptides
Valйrie Leclиre, Tilmann Weber, Philippe Jacques, and Maude Pupin
15. The Use of ClusterMine360 for the Analysis of Polyketide and Nonribosomal Peptide Biosynthetic Pathways
Nicolas Tremblay, Patrick Hill, Kyle R. Conway, and Christopher N. Boddy
16. Alignment-Free Methods for the Detection and Specificity Prediction of Adenylation Domains
Guillermin Agьero-Chapin, Gisselle Pйrez-Machado, Aminael Sбnchez-Rodrнguez, Miguel Machado Santos, and Agostinho Antunes
17. Characterization of Nonribosomal Peptide Synthetases with NRPSsp
C
arlos Prieto
Автор: Hoshino Akina, Lindberg Iris Название: Peptide Biosynthesis: Prohormone Convertases 1/3 and 2 ISBN: 1615043640 ISBN-13(EAN): 9781615043644 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 33440.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The prohormone convertases (PC) 1/3 and 2 are calcium-activated eukaryotic subtilisins with low pH optima which accomplish the limited proteolysis of peptide hormone precursors within neurons and endocrine cells. This title reviews the biochemistry, regulation, and roles of PC1/3 and 2 in disease, with an emphasis on the work published in the last 10 years.
Автор: Petersson, E.James Название: Synthetic And Enzymatic Modifications Of The Peptide Backbone,655 ISBN: 0128212535 ISBN-13(EAN): 9780128212530 Издательство: Elsevier Science Рейтинг: Цена: 175170.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
Автор: Carlos Amada Figueiredo Название: Steroids: Biosynthesis, Functions & Health Implications ISBN: 1620812770 ISBN-13(EAN): 9781620812778 Издательство: Nova Science Рейтинг: Цена: 211190.00 T Наличие на складе: Невозможна поставка. Описание: The rapid pace of technological change constantly gives rise to new ethical dilemmas. This provides a practical introduction for engineering students that emphasizes ethical decision-making. The authors situate engineering ethics in the wider context of business and environmental ethics and guide students through case studies emphasizing value conflicts often encountered in engineering.
Автор: Hiroshi Ashihara, Alan Crozier, Iziar A. Ludwig Название: Plant Nucleotide Metabolism: Biosynthesis, Degradation, and Alkaloid Formation ISBN: 1119476127 ISBN-13(EAN): 9781119476122 Издательство: Wiley Рейтинг: Цена: 166790.00 T Наличие на складе: Поставка под заказ. Описание: Raymond Murphy`s English Grammar in Use is the first choice for intermediate (B1-B2) learners and covers all the grammar you will need at this level. This book with answers has clear explanations and practice exercises that have helped millions of people around the world improve their English. It is perfect for self-study and can also be used by teachers as a supplementary book in classrooms.
Автор: Andrew H Keller, Michelle D Fallon Название: Auxins: Structure, Biosynthesis & Functions ISBN: 1621005046 ISBN-13(EAN): 9781621005049 Издательство: Nova Science Рейтинг: Цена: 149940.00 T Наличие на складе: Невозможна поставка. Описание: During World War II, Academy Award-winning director Frank Capra made propaganda films for the U.S. Government, such as Prelude to War, The Nazis Strike, The Battle of Britain, War Comes to America and The Negro Soldier. This analyses the cinematic and thematic techniques Capra employed in these films, linking them to the techniques and ideology of the director`s popular mainstream narrative films.
Автор: Kirk Weaver, Clayton Kelley Название: Trypsin: Structure, Biosynthesis & Functions ISBN: 1619423197 ISBN-13(EAN): 9781619423190 Издательство: Nova Science Рейтинг: Цена: 211190.00 T Наличие на складе: Невозможна поставка. Описание: Trypsin is a serine protease in the digestive system of humans and animals. This book presents current research in the structure, biosynthesis and functions of trypsin. Topics include the study of trypsins from submammalian vertebrates with special emphasis on fish; the applications of trypsin in food processing; trypsin acting as an activating enzyme in gut innate immunity and protease-activated receptor 2 in the enteric nervous system.
Автор: Fachuang Lu, Fengxia Yue Название: Lignin: Biosynthesis, Functions and Economic Significance ISBN: 1536147699 ISBN-13(EAN): 9781536147698 Издательство: Nova Science Рейтинг: Цена: 215410.00 T Наличие на складе: Невозможна поставка. Описание: Lignin is the main natural resource of aromatic structures on Earth. With the depletion of fossil oil and increased environmental concerns, renewable resources for energy and chemical production have attracted tremendous attention from scientists and engineers. As a renewable aromatic polymer, lignin has been, for a long time, studied in terms of its biosynthesis, structures, reactivities and applications although few portions of lignins available from the industry, mainly pulping mills, have been utilized for various applications. The key for complete and efficient utilization of lignins is that all aspects, including lignin biosynthesis, structures, functionalities, and properties, about lignins should be understood. Another important attribute related to lignin utilization comes from analytical methods essential for our understanding of lignins and mechanisms involved in various processes. This book provides critical reviews and the latest research results relating to selected fields of lignin biosynthesis, functional characterization and applications.
Автор: Phyllis Santos Название: Salicylic Acid & Jasmonic Acid: Biosynthesis, Functions & Role in Plant Development ISBN: 1634821386 ISBN-13(EAN): 9781634821384 Издательство: Nova Science Рейтинг: Цена: 168950.00 T Наличие на складе: Невозможна поставка. Описание: Salicylic acid (SA) and methyl jasmonate (MJ) signaling is associated with phospholipids and the enzymes that metabolize them. However, despite the many studies conducted, the role of SA or MJ signalling via phospholipids in plant responses is not yet fully understood. The signaling pathways of SA and MJ have been evaluated in plant cell suspensions, and it was observed that these compounds regulate enzymatic activities to generate a rapid cellular response. This book discusses the immune responses induced by salicylic acid and jasmonic acids against plant parasites; the induction by SA of in vitro thermotolerance during thermotherapy; aalicylic acid, methyl jasmonate and phospholipid signaling in suspension cells; the self-association of salicylic acid derivatives in aqueous solutions studied by methods of absorption and fluorescence; and the role of exogenous salicylic acid applications for salt tolerance in tomato plants.
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