Nonribosomal Peptide and Polyketide Biosynthesis, Bradley Evans

Название: Secondary-metabolite biosynthesis and metabolism
ISBN: 1461363128 ISBN-13(EAN): 9781461363125
Издательство: Springer
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Цена: 113190.00 T
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Описание: Proceedings of an American Chemical Society symposium held in Atlanta, Georgia, April 14-19, 1991

Автор: Carlos Amada Figueiredo
Название: Steroids: Biosynthesis, Functions & Health Implications
ISBN: 1620812770 ISBN-13(EAN): 9781620812778
Издательство: Nova Science
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Цена: 211190.00 T
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Описание: The rapid pace of technological change constantly gives rise to new ethical dilemmas. This provides a practical introduction for engineering students that emphasizes ethical decision-making. The authors situate engineering ethics in the wider context of business and environmental ethics and guide students through case studies emphasizing value conflicts often encountered in engineering.

Автор: Bradley Evans
Название: Nonribosomal Peptide and Polyketide Biosynthesis
ISBN: 1493933736 ISBN-13(EAN): 9781493933730
Издательство: Springer
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Цена: 130430.00 T
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Описание:

This volume presents an overview of nonribosomal peptide synthetase (NRPS) and polyketide synthase (PKS) structure and function. It then continues with methods for the analysis of these pathways including conventional enzymological assays, contemporary mass spectrometric analysis techniques, specialized molecular biological approaches applicable to NRPSs and PKSs, and small molecule analysis tools tailored to this very special class of natural products, and concludes by examining bioinformatics tools for the analysis of these enzymes, pathways, and molecules. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Автор: Matthew Jenner
Название: Using Mass Spectrometry for Biochemical Studies on Enzymatic Domains from Polyketide Synthases
ISBN: 3319327224 ISBN-13(EAN): 9783319327228
Издательство: Springer
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Цена: 95770.00 T
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Описание: Introduction.- Materials and Methods.- Substrate Specificity of Ketosynthase Domains Part I: β-Branched Acyl Chains.- Substrate Specificity of Ketosynthase Domains Part II: Amino Acid-Containing Acyl Chains.- Synthesis of Acyl-Acyl Carrier Proteins and their use in Studying Polyketide Synthase Enzymology.- Substrate Specificity of Ketosynthase Domains Part III: Elongation-Based Substrate Specificity.

Автор: Calista Araujo, Demetrio Perez
Название: Triglycerides: Chemical Structure, Biosynthesis & Role in Disease
ISBN: 1624177271 ISBN-13(EAN): 9781624177279
Издательство: Nova Science
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Цена: 196410.00 T
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Описание: The boundary between semantics and pragmatics has been important since the early twentieth century, but in the last twenty-five years it has become the central issue in the philosophy of language. This anthology collects classic philosophical papers on the topic, along with recent key contributions. It stresses not only the nature of the boundary, but also its importance for philosophy generally.

Автор: Karl Freudenberg; A. C. Neish
Название: Constitution and Biosynthesis of Lignin
ISBN: 3540042741 ISBN-13(EAN): 9783540042747
Издательство: Springer
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Цена: 95770.00 T
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Описание: Among terrestrial plants the vascular plants are the largest and the most con- spicuous. Thus lignin is found in vascular plants such as lycopods, ferns, gymnosperms and angiosperms, whereas it is absent from simple plants such as fungi, and from all other organisms.

Автор: Tracey Rouault
Название: Biochemistry, Biosynthesis and Human Diseases
ISBN: 3110479397 ISBN-13(EAN): 9783110479393
Издательство: Walter de Gruyter
Цена: 123910.00 T
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Описание: This volume on iron-sulfur proteins includes chapters that discuss how microbes, plants, and animals synthesize these complex prosthetic groups, and why it is important to understand the chemistry and biogenesis of iron sulfur proteins. In addition to their vital importance in mitochondrial respiration, numerous iron sulfur proteins are important in maintenance of DNA integrity. Multiple rare human diseases with different clinical presentations are caused by mutations of genes in the iron sulfur cluster biogenesis pathway. Understanding iron sulfur proteins is important for understanding a rapidly expanding group of metabolic pathways important in all kingdoms of life, and for understanding processes ranging from nitrogen fixation to human disease.

Автор: Bouzid Nedjimi
Название: Proline: Biosynthesis, Regulation & Health Benefits
ISBN: 1622577396 ISBN-13(EAN): 9781622577392
Издательство: Nova Science
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Цена: 168950.00 T
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Описание: The critical introduction to this Broadview Edition gives particular emphasis to Wells`s hostility towards religion as well as his thorough knowledge of the Darwinian thought of his time. Appendices provide passages from Darwin and Huxley related to Wells`s early writing; in addition, excerpts from other writers illustrate late-nineteenth-century anxieties about social degeneration.

Автор: Constantin A. Rebeiz
Название: Chlorophyll Biosynthesis and Technological Applications
ISBN: 9400771339 ISBN-13(EAN): 9789400771338
Издательство: Springer
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Цена: 174150.00 T
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Описание: This monograph offers an in depth examination of the chlorophyll (Chl) biosynthetic pathway. It covers plant physiology, biochemistry, biophysics, and molecular biology.

Автор: Harvey Williams, Patricia Kelly
Название: Polyhydroxyalkanoates: Biosynthesis, Chemical Structures and Applications
ISBN: 1536134392 ISBN-13(EAN): 9781536134391
Издательство: Nova Science
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Цена: 257650.00 T
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Описание: Polyhydroxyalkanoates: Biosynthesis, Chemical Structures and Applications opens with an expose on employing extremophiles as polyhydroxyalkanoate (PHA) producers. The authors suggest that extremophiles may be easily subjected to a long-term continuous cultivation processes, which considerably enhances overall productivity while reducing the energy demand in biopolymer production. Conversely, a range of challenges remain, including improving the metabolic capability of extremophiles, recycling of fermentation broth, various process engineering aspects, and adaptation of bioreactor materials and process controlling devices to conditions shortening their life span. Following this, the enzymes, regulators and genes involved in PHA biosynthesis are analyzed for their potential as an alternative to synthetic polymers. They are synthesized as intracellular carbon and energy storage compounds from over 300 species in the presence of excess carbon and under oxygen, nitrogen or phosphorus limitation, or after pH shifts. This collection goes on to suggest PHA as a promising alternative for petrochemical compounds. The challenges of increasing economic feasibility in the global market, minimizing costs, and improving the polymer yield are reviewed. Additionally, recent research on structural variations of PHAs has been centered on the design, biosynthesis, and properties of biodegradable and biocompatible materials, which can be used for bioengineering. This collection also includes a focus on the roles of polyhydroxyesters and PHAs in the construction of tissue engineering scaffolds, which are used in bone, cartilage, ligament, skin, vascular tissues, neural tissues and skeletal muscles. Their exceptional properties, such as high surface-to-volume ratio, high porosity with very small pore size, and biodegradation have made them gain a lot of attention in this field. The biomedical applications of PHAs are explored, including in-vivo implants, tissue engineering, anticancer agents, drug delivery, biocontrol agents and memory enhancers, as their low acidity allows for minimal risk in usage. In order to enhance its applicability in various fields, the blends and nanocomposites of PHAs are studied and their potential challenges, applications and opportunities are addressed. After which, the industrial and agricultural applications are described, with specific focus on potential applications of PHAs in packaging. Other applications include moulded goods, paper coatings, non-woven fabrics, adhesives, films and performance additives. Recent advances in this area, by means of peer-reviewed literature and patents, are introduced and discussed. Moreover, innovative strategies for the synthesis of novel polymer blends, adequate for food contact applications, are presented.

Автор: Jason M OKeefe
Название: Arachidonic Acid: Sources, Biosynthesis & Health Effects
ISBN: 1631176196 ISBN-13(EAN): 9781631176197
Издательство: Nova Science
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Цена: 257650.00 T
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Описание: There have been dramatic changes in the technologies available for hemodynamic monitoring in recent years. This unique book provides clinicians and administrators with a comprehensive understanding of perioperative hemodynamic monitoring and goal directed therapy, emphasizing practical guidance for implementation at the bedside and evaluating hemodynamic monitoring systems in clinical practice.

Автор: Fachuang Lu, Fengxia Yue
Название: Lignin: Biosynthesis, Functions and Economic Significance
ISBN: 1536147699 ISBN-13(EAN): 9781536147698
Издательство: Nova Science
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Цена: 215410.00 T
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Описание: Lignin is the main natural resource of aromatic structures on Earth. With the depletion of fossil oil and increased environmental concerns, renewable resources for energy and chemical production have attracted tremendous attention from scientists and engineers. As a renewable aromatic polymer, lignin has been, for a long time, studied in terms of its biosynthesis, structures, reactivities and applications although few portions of lignins available from the industry, mainly pulping mills, have been utilized for various applications. The key for complete and efficient utilization of lignins is that all aspects, including lignin biosynthesis, structures, functionalities, and properties, about lignins should be understood. Another important attribute related to lignin utilization comes from analytical methods essential for our understanding of lignins and mechanisms involved in various processes. This book provides critical reviews and the latest research results relating to selected fields of lignin biosynthesis, functional characterization and applications.