Автор: Pitha Paula M. Название: Interferon: / The 50th Anniversary ISBN: 354071328X ISBN-13(EAN): 9783540713289 Издательство: Springer Рейтинг: Цена: 204970.00 T Наличие на складе: Невозможна поставка. Описание: Over the last half of century interferon (IFN), originally discovered as an antiviral protein, has developed from an inhibitor of viral replication to a major force in the antiviral response. Initially studied only by few virologists, IFN was generally considered as a poorly defined protein of limited importance. The development of molecular techniques lead to the identification of a family of IFN genes and has shown an unexpected complexity of type I IFN genes and their expression. Presently, some aspects of the of the pathogen mediated induction of IFN gene expression are understood at molecular level, while others are still at the stage of description. Both Toll like receptors and cytoplasmic RNA helicases were shown to recognize viral nucleic acids and the basis of a distinct recognition of viral nucleic acids from the cellular ones are emerging. Important insights on the virus recognition entity, leading to the expression of interferon and interferon induced genes, have been made in the recent year, which are challenging the accepted concept of the critical role of dsRNA in IFN induction. The availability of genetically modified mice that are lacking either essential components of the interferon inducing pathway, or interferon signaling pathway fully confirmed the original idea, made soon after its discovery, that interferon is the first cellular defense against viral infection.
Автор: Paula M. Pitha Название: Interferon: The 50th Anniversary ISBN: 3642090443 ISBN-13(EAN): 9783642090448 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A vital text for researchers and clinicians in the fields of virology and oncology alike, this book is a comprehensive guide to one of medicine`s most important tools that covers the most recent research. Important insights have been made in recent months that are challenging the accepted concept of the critical role of dsRNA in IFN induction.
Автор: Yechiel Becker Название: Antiviral Drugs and Interferon: The Molecular Basis of Their Activity ISBN: 0898386438 ISBN-13(EAN): 9780898386431 Издательство: Springer Рейтинг: Цена: 231990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Research on antiviral drugs and their mode of action in infected cells. Recent studies on antivirals that are activated by the herpes simplex virus type l-coded thy- midine kinase from a prod rug to an antiviral drug have opened new directions in the development of effective antiviral drugs.
Автор: M. Costa; H. Kirchner; U. Klotz; J. Kraker; R. Pat Название: Essential and Non-Essential Metals Metabolites with Antibiotic Activity Pharmacology of Benzodiazepines Interferon Gamma Research ISBN: 3642698743 ISBN-13(EAN): 9783642698743 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Scientific progress, more and more, makes it possible to relate disease to irreg- ularities on a molecular basis. Werner (FRG) . . . . . . . . . . . . . . . . . . . . . . . 47 . . . . .
Автор: K. Cantell; H. Schellekens Название: The Biology of the Interferon System 1986 ISBN: 9401080844 ISBN-13(EAN): 9789401080842 Издательство: Springer Рейтинг: Цена: 81050.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the 1986 ISIR-TNO meeting held at the Dipoli Congress Center, Espoo, Finland, September 7-12, 1986
Автор: Yechiel Becker Название: Antiviral Drugs and Interferon: The Molecular Basis of Their Activity ISBN: 1461338069 ISBN-13(EAN): 9781461338062 Издательство: Springer Рейтинг: Цена: 231990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Research on antiviral drugs and their mode of action in infected cells. Recent studies on antivirals that are activated by the herpes simplex virus type l-coded thy- midine kinase from a prod rug to an antiviral drug have opened new directions in the development of effective antiviral drugs.
Автор: W.E.G. M?ller; H.C. Schr?der Название: Biological Response Modifiers — Interferons, Double-Stranded RNA and 2?,5?-Oligoadenylates ISBN: 3642785514 ISBN-13(EAN): 9783642785511 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Biological response modifiers are increasingly used in viral and cancer therapy. Since alterations of the immune system are the primary symptoms of HIV infection, especially therapies directed towards the modulation of the immune response have been under intense evaluation.
Автор: Michel Revel Название: Clinical Aspects of Interferons ISBN: 1461289777 ISBN-13(EAN): 9781461289777 Издательство: Springer Рейтинг: Цена: 241310.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Michel Revel Название: Clinical Aspects of Interferons ISBN: 0898383714 ISBN-13(EAN): 9780898383713 Издательство: Springer Рейтинг: Цена: 241310.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
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