Автор: Xu, Jun-Ping (School of Molecular Science, Arizona State University) Название: Cancer Inhibitors from Chinese Natural Medicines ISBN: 1032097396 ISBN-13(EAN): 9781032097398 Издательство: Taylor&Francis Рейтинг: Цена: 48990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Nature is an attractive source of therapeutic and preventive compounds, and with such chemical diversity found in millions of species of plants, over 60% of currently used anticancer agents are derived from natural sources. Cancer Inhibitors from Chinese Natural Medicines summarizes new advancements in the experimental and clinical
Автор: Ganai, Shabir Ahmad Название: Natural hdac inhibitors for epigenetic combating of cancer progression ISBN: 1032279869 ISBN-13(EAN): 9781032279862 Издательство: Taylor&Francis Рейтинг: Цена: 94930.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This Book entitled "Natural HDAC Inhibitors for Epigenetic Combating of Cancer Progression" deals only with HDAC inhibitors from natural origin including bacteria, fungi, marine organisms and notably from diverse plant sources.
Автор: Curtin Nicola J., Sharma Ricky A. Название: Parp Inhibitors for Cancer Therapy ISBN: 3319344897 ISBN-13(EAN): 9783319344898 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role of PARP in cancer therapy. The volume covers the history of the discovery of PARP (poly ADP ribose polymerase) and its role in DNA repair. In addition, a description of discovery of the PARP family, and other DNA maintenance-associated PARPs will also be discussed. The volume also features a section on accessible chemistry behind the development of inhibitors. PARP inhibitors are a group of pharmacological inhibitors that are a particularly good target for cancer therapy. PARP plays a pivotal role in DNA repair and may contribute to the therapeutic resistance to DNA damaging agents used to treat cancer. Researchers have learned a tremendous amount about the biology of PARP and how tumour-specific defects in DNA repair can be exploited by PARPi. The “synthetic lethality” of PARPi is an exciting concept for cancer therapy and has led to a heightened activity in this area.
Автор: Hoffman, E.J. Название: Cancer and the Search for Selective Biochemical Inhibitors ISBN: 0367388936 ISBN-13(EAN): 9780367388935 Издательство: Taylor&Francis Рейтинг: Цена: 63280.00 T Наличие на складе: Нет в наличии. Описание:
The world of medicine has become splintered into two factions, that of orthodoxy and its counterpart, alternative or complementary medicine. A problem with alternative medicine is, of course, that of anecdote and hearsay. The solution: the disclosure, in an unassailable fashion, of the underlying biochemical principles for alternative cancer therapies.
Cancer and the Search for Selective Biochemical Inhibitors, Second Edition delineates the underlying biochemical principles for alternative cancer therapies. Completely revised and updated, this edition includes coverage of the link between concepts and practices of alternative and conventional medicine. The author examines anticancer plant substances and other alternatives such as Vitamin C, essiac tea, shark cartilage, and cat's claw. The text also addresses the problem of determining selective and non-toxic enzyme inhibitors for cancer cell metabolic pathways.
While an increased number of allopathic professionals are in tune with alternative therapies, the integration of the two factions is far from the norm. Keeping the same format that made its predecessor a benchmark text, this book compares complementary, alternative, and integrative treatments with chemotherapy and other more traditional treatments.
Автор: Daniele Focosi Название: Resistance to Tyrosine Kinase Inhibitors ISBN: 3319460900 ISBN-13(EAN): 9783319460901 Издательство: Springer Рейтинг: Цена: 156720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors.
Автор: Vitaly A. Polunovsky; Peter J. Houghton Название: mTOR Pathway and mTOR Inhibitors in Cancer Therapy ISBN: 1617796948 ISBN-13(EAN): 9781617796944 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The target of rapamycin (TOR) was rst identi ed in Saccharomyces cerevisiae and subsequently in mammals (mTOR) as a conserved atypical serine/threonine kinase. Rapamycin was isolated as a product of the soil bacteria Streptomyces hygroscopicus, identi ed in a soil sample taken from the island of Rapa Nui (Easter Island).
Автор: Satya Prakash Gupta Название: Cancer-Causing Viruses and Their Inhibitors ISBN: 1138374830 ISBN-13(EAN): 9781138374836 Издательство: Taylor&Francis Рейтинг: Цена: 60220.00 T Наличие на складе: Невозможна поставка. Описание:
Cancer-causing viruses, also called oncoviruses, play a key role in the development of certain cancers. They contribute to genetic changes that disrupt the cell cycle machinery, interfering with functions such as cell growth. Cancer-Causing Viruses and Their Inhibitors presents a plethora of research from internationally reputed contributors who discuss different types of oncoviruses, their mechanisms of invasion and growth, and their life cycles.
The book begins with an overview of the oncoviruses discovered to date and includes a brief description of their structures, genotypes, replication, and mechanisms of infection leading to cancers. It then explores several of these viruses in detail, including:
Human T-cell leukemia virus type 1 (HTLV-1)
Hepatitis C virus (HCV)
Epstein-Barr virus (EBV)
Human papilloma virus (HPV)
Human herpes virus 8 (HHV-8)/Kaposi's sarcoma-associated herpes virus (KSHV)
Human immunodeficiency virus (HIV/AIDS)
Oncolytic viruses
This book is an essential reference for those working in virology, oncology, and biotechnology. The discoveries presented will enable researchers and clinicians to optimize both historical and current approaches to anti-viral therapies.
Автор: Ward Alister C. Название: Stat Inhibitors in Cancer ISBN: 3319827014 ISBN-13(EAN): 9783319827018 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context.
Автор: Zou Taotao Название: Anti-Cancer N-Heterocyclic Carbene Complexes of Gold(iii), Gold(i) and Platinum(ii): Thiol "switch-On " Fluorescent Probes, Thioredoxin Reductase Inhib ISBN: 9811092214 ISBN-13(EAN): 9789811092213 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Detailed chemical synthesis, in vitro and/or in vivo anti-cancer activities are clearly presented including: (i) a class of Au(III) complexes containing a highly fluorescent N^N^N ligand and NHC ligand that simultaneously act as fluorescent thiol "switch-on" probes and anti-cancer agents;
Автор: Focosi Daniele Название: Resistance to Tyrosine Kinase Inhibitors ISBN: 331983438X ISBN-13(EAN): 9783319834382 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors.
Автор: Ward Название: STAT Inhibitors in Cancer ISBN: 3319429477 ISBN-13(EAN): 9783319429472 Издательство: Springer Рейтинг: Цена: 148020.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume, which includes contributions from leading scientists and clinicians in the field, provides definitive, state-of-the-art information on STAT inhibitors in a biological and clinical context. It gives an overview of the biology of the STAT family of transcription factors and their role in cancer etiology. Additionally, it describes the raft of therapeutic approaches being used to inhibit STATs in the context of various cancers, covering the full spectrum of therapeutic approaches to inhibiting STATs, and presenting emerging data from clinical trials.
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