Natural Products : Alternate Therapeutic as Quorum Sensing (QS) Inhibitors, Moupriya Nag
Автор: Maheshwari Название: Natural Products as Enzyme Inhibitors ISBN: 9811909318 ISBN-13(EAN): 9789811909313 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Chapters in this book cover topics such as plant-derived inhibitors of serine proteases, pancreatic lipase (PL) inhibitors from indigenous medicinal plants, amylase inhibitors and their applications in agriculture and food processing industries and advances in silico techniques used in the study of enzyme inhibitors.
Автор: Maheshwari Название: Natural Products as Enzyme Inhibitors ISBN: 9811909342 ISBN-13(EAN): 9789811909344 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Нет в наличии. Описание: This book provides an overview of the latest developments and future challenges in enzyme inhibitor research. It discusses the general enzyme inhibitory principles and mechanisms in enzyme activity regulation and application of enzyme inhibitors in different areas and sectors. The major areas of applications of enzyme inhibitors covered in this book are human health management, agriculture, food processing and research, which leads to drug discovery or enzyme activity mechanisms. The book also identifies the gaps in the existing knowledge and opens up new research ideas in this important area. Currently, most enzyme inhibitors are reported to inhibit various classes of enzymes. These enzyme inhibitors are the focus of the scientific community because they may answer an increasing array of questions in the research area of biological sciences, including biochemistry, medicine, physiology, pharmacy, agriculture, ecology etc. It also serves as a useful tool in the study of enzyme structures and reaction mechanisms and in the development of technologies in agriculture, food processing, and health management. Chapters in this book cover topics such as plant-derived inhibitors of serine proteases, pancreatic lipase (PL) inhibitors from indigenous medicinal plants, amylase inhibitors and their applications in agriculture and food processing industries and advances in silico techniques used in the study of enzyme inhibitors. The book will serve as a valuable resource for students and researchers in Life Sciences, agriculture, medicine, food processing, and allied industries.
Автор: Sir John R. Vane; Jack H. Botting Название: Selective COX-2 Inhibitors ISBN: 940106041X ISBN-13(EAN): 9789401060417 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: ` The elucidation of the crystal structure of these different enzymes and the skills of medicinal chemists have led to the synthesis of new chemicals with a selectivity for the inducible enzyme, and thus with therapeutic efficacy without those toxic effects result- ing from inhibition of the constitutive enzyme.
Автор: Ingo K. Mellinghoff; Charles L. Sawyers Название: Therapeutic Kinase Inhibitors ISBN: 3642445802 ISBN-13(EAN): 9783642445804 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Cancer drug development is currently undergoing a profound shift. Drugs targeting fundamental cellular processes such DNA-replication and microtubule function, often referred to as chemotherapy and still the backbone of most cancer treatment regimens, are increasingly being complemented by or replaced with kinase inhibitors. This new class of drugs targets enzymes which provide growth and survival signals to cancer cells by transferring phosphate groups from Adenosine-5'-triphosphate (ATP) to other proteins, lipids, nucleotides, and carbohydrates.
This book summarizes the current state of kinase inhibitor therapy for cancer. Successful drug development relies on the expertise and dedication of many experts. To reflect this team approach to finding new kinase inhibitors and defining their optimal use for cancer treatment, the editorsinvited experts in academia and pharmaceutical industry to share their insights into various aspects of this process, ranging from the first chemical screens, to preclinical testing and disease-focused clinical drug development. The editors and authorshope these lessons will be instructive for the novice as well as the expert. "
Автор: Martin Lorenz Stein Название: NMR-Bioassay Guided Isolation of the Natural 20S Proteasome Inhibitors from Photorhabdus Luminescens ISBN: 3319079131 ISBN-13(EAN): 9783319079134 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Martin Stein's thesis describes a novel methodology for natural product discovery. Due to its high degree of reproducibility, robustness and sensitivity, the technique can be utilized to detect even trace amounts of bioactive substances in heterogeneous matrices such as fermentation broths or crude organic extracts. This research is thus relevant for a large number of researchers working in natural product discovery. Applications of this novel NMR-based approach include suitable environmental triggers for the induction of biosynthetic machineries. The author demonstrates the extraordinary value of this approach by the successful isolation of two potent inhibitors of the pharmaceutically relevant proteasome core particle from the insect pathogen photorhabdus luminescens. This thesis has led to a number of publications in high-impact journals.
Название: Cancer Inhibitors from Chinese Natural Medicines ISBN: 1498787649 ISBN-13(EAN): 9781498787642 Издательство: Taylor&Francis Рейтинг: Цена: 433840.00 T Наличие на складе: Нет в наличии.
Автор: Martin Lorenz Stein Название: NMR-Bioassay Guided Isolation of the Natural 20S Proteasome Inhibitors from Photorhabdus Luminescens ISBN: 331938399X ISBN-13(EAN): 9783319383996 Издательство: Springer Рейтинг: Цена: 87060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Martin Stein`s thesis describes a novel methodology for natural product discovery. The author demonstrates the extraordinary value of this approach by the successful isolation of two potent inhibitors of the pharmaceutically relevant proteasome core particle from the insect pathogen photorhabdus luminescens.
Автор: V. Kefeli; Bruno Borsari; M.V. Kalevitch Название: Natural Growth Inhibitors and Phytohormones in Plants and Environment ISBN: 9048161983 ISBN-13(EAN): 9789048161980 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Therefore, this effort proposes a more holistic approach to the study of plant physiology, in which the plant-soil interactions are discussed, with a profound description of different allelochemicals and their effects on plants growth.
Автор: Xu, Jun-Ping (School of Molecular Science, Arizona State University) Название: Cancer Inhibitors from Chinese Natural Medicines ISBN: 1032097396 ISBN-13(EAN): 9781032097398 Издательство: Taylor&Francis Рейтинг: Цена: 48990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Nature is an attractive source of therapeutic and preventive compounds, and with such chemical diversity found in millions of species of plants, over 60% of currently used anticancer agents are derived from natural sources. Cancer Inhibitors from Chinese Natural Medicines summarizes new advancements in the experimental and clinical
Автор: Ganai, Shabir Ahmad Название: Natural hdac inhibitors for epigenetic combating of cancer progression ISBN: 1032279869 ISBN-13(EAN): 9781032279862 Издательство: Taylor&Francis Рейтинг: Цена: 94930.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This Book entitled "Natural HDAC Inhibitors for Epigenetic Combating of Cancer Progression" deals only with HDAC inhibitors from natural origin including bacteria, fungi, marine organisms and notably from diverse plant sources.
Автор: Tommonaro, Giuseppina Название: Quorum Sensing ISBN: 0128149051 ISBN-13(EAN): 9780128149058 Издательство: Elsevier Science Рейтинг: Цена: 110030.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease, is also governed by such communication signals.
Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms. It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application. This volume describes the QS mechanism from its molecular basis to medical applications such as antibiotic therapy and involvement of QS in pathologies. This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm. The broad scope of this title will be of significant use to researchers across several fields with interest in QS, including to microbiologists, chemists, biochemists and ecologists.
Describes Quorum Sensing (QS) mechanisms from their molecular basis, to their clinical applications
Spans several fields in relation to QS, including microbiology, chemistry, biochemistry and ecology
Considers QS as an approach to the discovery of new antibiotics
Looks at QS as a means to understand the microbial world and towards use of bacteria and their products in biotechnological applications
Summarizes key results on QS mechanisms' molecular basis and fields of application
Название: Trends in Quorum Sensing and Quorum Quenching ISBN: 0367224283 ISBN-13(EAN): 9780367224288 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Невозможна поставка. Описание: Quorum sensing or cell to cell communication is a key phenomenon responsible for plethora of activities and responses in both gram positive and gram negative bacteria. This book covers evolution of quorum sensing mechanism in bacteria and evaluate the potential application of quorum sensing inhibitors in the clinical and industrial settings.
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