Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Автор: Srivastava Sanjay K Название: Role of Capsaicin in Oxidative Stress and Cancer ISBN: 9400763166 ISBN-13(EAN): 9789400763166 Издательство: Springer Рейтинг: Цена: 130610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress and much more.
Автор: Bowery Norman G Название: Allosteric Receptor Modulation In Drug Targeting ISBN: 0824727916 ISBN-13(EAN): 9780824727918 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Невозможна поставка. Описание: Allosteric Receptor Modulation in Drug Targeting
Автор: Huang Название: Oxidative Stress ISBN: 9811605246 ISBN-13(EAN): 9789811605246 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Нет в наличии. Описание: In this book, the authors attempt to re-define the key concepts in oxidative stress, such as oxidative eustress and oxidative distress, revisit the pivotal signaling of oxidative stress in human diseases, and discuss the debate in current anti-oxidant strategies, such as natural products and drug repurposing.
Автор: Rattan Suresh I. S., Le Bourg Eric Название: Hormesis in Health and Disease ISBN: 1482205459 ISBN-13(EAN): 9781482205459 Издательство: Taylor&Francis Рейтинг: Цена: 178640.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Some mild stresses have positive effects on survival and aging as shown in animal models. There is also a large body of research that demonstrates these hormetic effects on aging, health, and resistance to severe stresses and diseases in human beings. However, the data are dispersed in the literature and are not always interpreted as hormetic effects. Hormesis in Health and Disease reviews the evidence for hormesis in humans as achieved through a variety of stresses or stimuli, and discusses mechanisms of hormesis and its ethical and legal issues.
Divided into four sections, this book presents the current state of research, including questions, debates, doubts, and controversies in hormesis. Section I covers the history and terminology of hormesis, describing its main features and providing necessary background information. Section II shows that hormetic effects can be caused by various stresses--including physical exercise, nutritional components, fasting, micronutrients, irradiation, heat, ischemia, and mental challenge--and can be observed both in organs and at the organism level. Section III reviews possible mechanisms of hormesis that have been elucidated at this point. Section IV discusses the wider consequences hormesis may have for everyone. This book demonstrates that health beneficial hormetic effects do exist in human beings. It offers information to inspire key players to initiate new strategies to elucidate the strengths and limits of the dual nature of stress.
Автор: Stephen M. Roberts; James P. Kehrer; Lars-Oliver K Название: Studies on Experimental Toxicology and Pharmacology ISBN: 331934708X ISBN-13(EAN): 9783319347080 Издательство: Springer Рейтинг: Цена: 121890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book focuses on data describing the roles of free radicals and related reactive species, and antioxidants, in the causes and treatments of diseases, examining both clinical and pre-clinical trials, as well as basic research.
Автор: Sanjay K. Srivastava Название: Role of Capsaicin in Oxidative Stress and Cancer ISBN: 9401784299 ISBN-13(EAN): 9789401784290 Издательство: Springer Рейтинг: Цена: 113180.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book describes the mechanism of the anti-cancer effects of capsaicin including the involvement of cytochrome P-450 in the bioactivation; identification of mitochondria as the key target site for oxidative stress and much more.
Автор: Ross G. Cameron; George Feuer Название: Apoptosis and Its Modulation by Drugs ISBN: 3642630251 ISBN-13(EAN): 9783642630255 Издательство: Springer Рейтинг: Цена: 348290.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: with contributions by numerous experts
Автор: H.J. Forman; Enrique Cadenas Название: Oxidative Stress and Signal Transduction ISBN: 1461377412 ISBN-13(EAN): 9781461377412 Издательство: Springer Рейтинг: Цена: 174150.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In the past few years there has been the increased recognition that the effects of oxidative stress are not limited to the damage of cellular constituents. The first deals with the immediate cellular responses to oxidative stress and the production of second messengers.
Автор: James E Barrett Название: Pharmacological Mechanisms and the Modulation of Pain,75 ISBN: 0128038837 ISBN-13(EAN): 9780128038833 Издательство: Elsevier Science Рейтинг: Цена: 198750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
"Pharmacological Mechanisms and the Modulation of Pain," the newest volume in the "Advances in Pharmacology" series, presents the pharmacological mechanisms and the modulation of pain. With a variety of chapters and the best authors in the field, this volume is an essential resource for pharmacologists, immunologists, and biochemists alike. Contains contributions from the best authors in the field of pharmacology that focus on the pharmacological mechanisms and modulation of painProvides an essential resource for pharmacologists, immunologists, and biochemists
Автор: Kenneth Hensley; Robert A. Floyd Название: Methods in Biological Oxidative Stress ISBN: 1617372005 ISBN-13(EAN): 9781617372001 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Methods in Biological Oxidative Stress is practical in scope, providing the details of up-to-date techniques for measuring oxidative stress and detecting oxidizing agents both in vitro and in vivo.
Автор: Ross G. Cameron; George Feuer Название: Apoptosis and Its Modulation by Drugs ISBN: 3540661212 ISBN-13(EAN): 9783540661214 Издательство: Springer Рейтинг: Цена: 391830.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: with contributions by numerous experts
Казахстан, 010000 г. Астана, проспект Туран 43/5, НП2 (офис 2) ТОО "Логобук" Тел:+7 707 857-29-98 ,+7(7172) 65-23-70 www.logobook.kz
