Автор: K.O. Stumpe; Karin Kraft; Alan I. Faden Название: Opioid Peptides and Blood Pressure Control ISBN: 3540189351 ISBN-13(EAN): 9783540189350 Издательство: Springer Рейтинг: Цена: 102480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A. , FADEN, K. KRAFr, and K. O. STUMPE Following the discovery of the pentapeptide enkephalins in 1975, a number of endogenous opioid peptides and opiate receptors have been identified. Endogenous opioids and opiate-receptor mechanisms have been implicated in a variety of regulat- ory and dysregulatory functions including analgesia, cardiovascular regulation, shock, hypertension, traumatic spinal cord and brain injury, stroke, immune func- tion, feeding behavior, diuresis, gastrointestinal motility, and respiratory control, among others. Over the past 10 years, many studies have demonstrated a relationship between endogenous opioids and the cardiovascular system under both homeostatic and pathophysiological conditions. Opioids and opiate receptors have been found in various cardioregulatory sites within the brain and spinal cord, as well as in peripheral tissues such as sympathetic ganglia, adrenal gland, and heart. Both endogenous opioids and exogenous opiates have been shown to produce potent cardiovascular effects following central nervous system or systemic administration. Opiate-receptor antagonists have been demonstrated to reverse hypotension from sepsis, hypo- volemia, and anaphylaxis; such studies have been used to infer activity of endogenous opioid systems in shock. Changes in tissue concentrations of endogenous opioids and or opiate receptors have been found after shock and hypertension, further implying a role for opioid systems in the etiology of these conditions. In addition, modification of opiate receptor regulation, receptor binding, or opioid metabolism has also been used to establish a potential role for endogenous opioid systems in cardiovascular control and dyscontrol.
Автор: David R. Brown; A. Alemayehu; B. Amiranoff; D.L. B Название: Gastrointestinal Regulatory Peptides ISBN: 364277816X ISBN-13(EAN): 9783642778162 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Authored by an array of internationally distinguished scientists, it deals with issues of peptide localization and biosynthesis in gastrointestinal cells, mechanisms of peptide release and inactivation and the nature of peptide receptors.
Автор: Martin C. Michel Название: Neuropeptide Y and Related Peptides ISBN: 3642622828 ISBN-13(EAN): 9783642622823 Издательство: Springer Рейтинг: Цена: 279500.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: with contributions by numerous experts
Автор: Jiaju Zhou Название: Peptides and Others ISBN: 3110654024 ISBN-13(EAN): 9783110654028 Издательство: Walter de Gruyter Цена: 215030.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This 8-volume set provides a systematic description on 8,350 active marine natural products from 3,025 various kinds of marine organisms. The diversity of structures, biological resources and pharmacological activities are discussed in detail. Molecular structural classification system with 264 structural types are developed as well. The 8th volume mainly illustrates the molecular formula and structures of peptides and other products.
Название: Handbook of Cell-Penetrating Peptides ISBN: 0367390485 ISBN-13(EAN): 9780367390488 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Since the first Handbook of Cell-Penetrating Peptides was prepared in 2001, the wealth of new information on the use of these peptides as transport systems has in fact served to confound the field. The constant internal change in the field of cell-penetrating peptides (CPPs) is due to recent research uncovering apparent ambiguities in cellular uptake. There is still neither a common terminology nor a uniform explanation for the penetrative mechanism of cell-penetrating peptides.
In this second edition of the Handbook of Cell-Penetrating Peptides, the authors summarize the current state of the field including recent reevaluations of earlier studies of CPP mechanisms. Beginning with an overview of the classes of peptides and their individual uptake mechanisms, from the earlier lipid models to the more recent endocytotic pathways, the book demonstrates the diversity and the opportunity for these biologically active proteins to serve as future drug leads. The text then covers the use of CPPs in gene modulation, addressing the application of antisense and decoy oligonucleotides, as well as the new avenue of research targeting specific tumors and other tissues-questions that had barely been asked when the first edition was published. By summarizing the diffuse information regarding CPPs, including the ambiguities and variety of mechanisms, the Handbook of Cell-Penetrating Peptides provides the most solid foundation available from which to expand the potential of this rapidly growing field of medicine.
Автор: Maria Emilova Velinova Название: Antimicrobial Peptides ISBN: 177361083X ISBN-13(EAN): 9781773610832 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 129580.00 T Наличие на складе: Невозможна поставка. Описание: Provides an introduction to the history, structure, classification and mechanism of action of antimicrobial peptides (AMPs). In this book, AMPs are categorized by their target and mode of action. For natural AMPs, we will emphasis on those from eukaryotes.
Название: Bioactive Peptides ISBN: 0367385732 ISBN-13(EAN): 9780367385736 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Focuses on Biology, Pharmacology, and Therapeutic Applications
The study and diverse applications of bioactive peptides traverse many sub-disciplines within chemistry, biology, physics, and medicine. Answering a long-standing need, Bioactive Peptides focuses on the biology, pharmacology, and therapeutic applications of endogenous peptide mediators and their analogues. Moving peptide science beyond chemical synthesis strategies and into the realms of peptide biology and therapeutics, it presents the overall contribution that peptide science has made to molecular, cellular, and whole organism biology, while also discussing future targets and therapeutic applications.
Beneficial for Experts and Novices Alike
Part I provides details of bioactive peptides that interact with common drug targets and analyzes some of the most competitive areas of current research worldwide. While it is widely known that mammalian physiological systems utilize bioactive peptides that have yet to be discovered, other animals provide a rich and valuable source of bioactive peptides. This fascinating area of science is the theme of Part II.Parts III and IV investigate the unique bioactivities of various peptides that are ripe for further exploration.
This definitive reference also includes:
A detailed description and analysis of a broad range of peptides that interact with G protein-coupled receptors, the quantitatively dominant drug target
A discussion of non-ribosomal peptides, which hold promise as sources of endogenous mediators
Important examples of common methodologies employed to identify, characterize, and further develop bioactive peptides from a range of natural sources
With mounting worldwide interest in their therapeutic potential, bioactive peptides-includ
Автор: Franco Fraschini; Russel J. Reiter Название: Role of Melatonin and Pineal Peptides in Neuroimmunomodulation ISBN: 1461366739 ISBN-13(EAN): 9781461366737 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of a NATO ARW held in Erice, Sicily, Italy, June 3-9, 1990
Автор: M. Zouhair Atassi; Garvin S. Bixler Название: Immunobiology of Proteins and Peptides VIII ISBN: 1461357713 ISBN-13(EAN): 9781461357711 Издательство: Springer Рейтинг: Цена: 104480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the Eighth International Symposium held in Pio Rico, Arizona, November 16-20, 1994
Автор: Anne-Marie Sapse Название: Molecular Orbital Calculations for Amino Acids and Peptides ISBN: 1461271096 ISBN-13(EAN): 9781461271093 Издательство: Springer Рейтинг: Цена: 87070.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume describes in detail the technique of molecular orbital calculations for biochemistry. The level of presentation will be accessible to biochemists, and biophysicists.
Автор: M. Z. Atassi Название: Immunobiology of Proteins and Peptides-III ISBN: 1468479768 ISBN-13(EAN): 9781468479768 Издательство: Springer Рейтинг: Цена: 104480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This symposia series, founded in 1976, is devoted to the advancement and dissemination of knowledge in the field in immunology, particularly as it relates to the immune recognition and responses to protein and peptide antigens.
Автор: Jean E. Rivier; G.R. Marshall Название: Peptides ISBN: 9401090629 ISBN-13(EAN): 9789401090629 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the Eleventh American Peptide Symposium, July 9-14, 1989, La Jolla, California, USA
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