Автор: Jose M. Cuezva; Ana M. Pascual-Leone; Mulchand S. Название: Endocrine and Biochemical Development of the Fetus and Neonate ISBN: 146159569X ISBN-13(EAN): 9781461595694 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The annual meeting of the Perinatal Biochemical Group of the Spanish Biochemical Society held in Madrid on December 15-16, 1989, provided an excellent opportunity to bring together a group of distinguished investigators both from Spain and from abroad with a common interest in developmental endocrinology and biochemistry.
Автор: Nelson D. Horseman Название: Prolactin ISBN: 1461356768 ISBN-13(EAN): 9781461356769 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Be- cause of the historical and practical importance of knowledge regarding the hypothala- mus-Iactotroph axis, the first chapters of this volume are dedicated to reviewing the physiology, development, and cell biology of lactotroph regulation.
Автор: Claude Kordon; I. Robinson; Jacques Hanoune; R. Da Название: Brain Somatic Cross-Talk and the Central Control of Metabolism ISBN: 3540000909 ISBN-13(EAN): 9783540000907 Издательство: Springer Рейтинг: Цена: 213360.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In mammals, a robust physiologic system acts to maintain relative constancy of weight. A key element of this system is leptin. The nature of this "brain-somatic" cross talk is as yet poorly understood, but it is likely to have important implications for the pathophysiology and treatment of obesity, diabetes and other metabolic disorders.
Автор: H. James Armbrecht; T.F. Williams; Rodney M. Coe; Название: Endocrine Function and Aging ISBN: 1461279305 ISBN-13(EAN): 9781461279303 Издательство: Springer Рейтинг: Цена: 97820.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: One of the hallmarks of aging is the decreased capacity to adapt to changes in the environment. Hormones, pro- hormones, hormone receptors, and "second messenger" mediators rapidly are being cloned and sequenced.
Автор: Terry W. Moody Название: Neural and Endocrine Peptides and Receptors ISBN: 1468451545 ISBN-13(EAN): 9781468451542 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The six plenary sessions emphasized pituitary peptides, releasing factors, brain peptides, growth factors, peripheral peptides, and clinical applications. Dr. Axelrod discussed numerous factors, such as the peptides CRF, VIP, and somatostatin, that regulate hormone secretion from pituitary cells.
Название: Endocrine disruptors ISBN: 0367454262 ISBN-13(EAN): 9780367454265 Издательство: Taylor&Francis Рейтинг: Цена: 63280.00 T Наличие на складе: Невозможна поставка. Описание: From epidemiology to etiology, this volume examines the reproductive and health hazards of endocrine-disrupting environmental chemicals. Divided into two sections, the first part describes the effects of environmental toxicants on the female reproductive system with an emphasis on the effects and mechanisms of their action during development. It
Автор: Schiraldi, David Название: Chemical and Biochemical Physics ISBN: 1771883022 ISBN-13(EAN): 9781771883023 Издательство: Taylor&Francis Рейтинг: Цена: 122490.00 T Наличие на складе: Нет в наличии.
Автор: Macheras Panos, Iliadis Athanassios Название: Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics: Homogeneous and Heterogeneous Approaches ISBN: 3319801813 ISBN-13(EAN): 9783319801810 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with epirical, compartmental, and stochastic pharmacokinetic models, with two new chapters, one on fractional pharmacokinetics and one on bioequivalence; and the fourth mainly with classical and nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. This second edition has new information on reaction limited models of dissolution, non binary biopharmaceutic classification system, time varying models, and interface models. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. This book will appeal to graduate students and researchers in pharmacology, pharmaceutical sciences, bioengineering, and physiology. Reviews of the first edition: "This book presents a novel modelling approach to biopharmaceutics, pharmacokinetics and pharmacodynamic phenomena. This state-of-the-art volume will be helpful to students and researchers in pharmacology, bioengineering, and physiology. This book is a must for pharmaceutical researchers to keep up with recent developments in this field." (P. R. Parthasarathy, Zentralblatt MATH, Vol. 1103 (5), 2007) "These authors are the unique (or sole) contributors in this area that are working on these questions and bring a special expertise to the field that is now being recognized as essential to understanding biological system and kinetic/dynamic characteristics in drug development...This text is an essential primer for those who would envision the incorporation of heterogeneous approaches to systems where homogeneous approaches are not sufficient to describe the system." (Robert R. Bies, Journal of Clinical Pharmacology, Vol. 46, 2006)
This book describes the reaction rate profiles of the ?-galactosidase-catalyzed conversion of lactose on the inner surface of a hollow fiber membrane, which is employed as an enzymatic reactor system. The reaction rate profiles were obtained by solving the mass transfer and kinetics of reaction in a 2-dimensional model of the system. The primary challenge of this research was to develop the kinetic model of the reaction to describe the kinetic behavior as the reaction occurred on the membrane surface. Despite the difficulties, the proposed model can reliably replicate the actual process, as validation procedures have confirmed. The reaction rates obtained analyze the performance of the immobilized enzyme on the membrane surface. Previously, an increase in performance of '?-galactosidase-catalyzed conversion of lactose assisted by ultrafiltration was suggested due to inhibitor removal. However, as the analysis presented here shows, the concentration profile of the substrate on the membrane surface also affects the reaction performance.
Автор: Charles E. Bugg; Steven E. Ealick Название: Crystallographic and Modeling Methods in Molecular Design ISBN: 1461279879 ISBN-13(EAN): 9781461279877 Издательство: Springer Рейтинг: Цена: 97820.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book contains the papers that were presented at the "Crystallo- graphic and Modeling Methods in Molecular Design Symposium" in Gulf Shores, Alabama, April 30 to May 3, 1989.
Автор: Kundu, Subhas Название: Biomaterials For 3D Tumor Modeling ISBN: 0128181281 ISBN-13(EAN): 9780128181287 Издательство: Elsevier Science Рейтинг: Цена: 263880.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Biomaterials for 3D Tumor Modeling reviews the fundamentals and most relevant areas of the latest advances of research of 3D cancer models, focusing on biomaterials science, tissue engineering, drug delivery and screening aspects. The book reviews advanced fundamental topics, including the causes of cancer, existing cancer models, angiogenesis and inflammation during cancer progression, and metastasis in 3D biomaterials. Then, the most relevant biomaterials are reviewed, including methods for engineering and fabrication of biomaterials. 3D models for key biological systems and types of cancer are also discussed, including lung, liver, oral, prostate, pancreatic, ovarian, bone and pediatric cancer.
This book is suitable for those working in the disciplines of materials science, biochemistry, genetics, molecular biology, drug delivery and regenerative medicine.
Reviews key biomaterials topics, including synthetic biomaterials, hydrogels, e-spun materials and nanoparticles
Provides a comprehensive overview of 3D cancer models for key biological systems and cancer types
Includes an overview of advanced fundamental concepts for an interdisciplinary audience in materials science, biochemistry, regenerative medicine and drug delivery
Автор: George A. Bray; ; Donna Ryan Название: Overweight and the Metabolic Syndrome: ISBN: 1441940731 ISBN-13(EAN): 9781441940735 Издательство: Springer Рейтинг: Цена: 213360.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This timely book provides an overview of topics related to obesity. These include associated health risks, childhood obesity, genetics, evaluation, treatment, behavioral strategies, and successes and failures in preventing obesity.
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