Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics: Homogeneous and Heterogeneous Approaches, Macheras Panos, Iliadis Athanassios

Автор: Macheras Panos, Iliadis Athanassios
Название: Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics / Homogeneous and Heterogeneous Approaches
ISBN: 0387281789 ISBN-13(EAN): 9780387281780
Издательство: Springer
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Цена: 55850.00 T
Наличие на складе: Поставка под заказ.
Описание: The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. www.springeronline.com

Автор: Panos Macheras; Athanassios Iliadis
Название: Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics
ISBN: 3319275968 ISBN-13(EAN): 9783319275963
Издательство: Springer
Рейтинг:
Цена: 111790.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this new second edition book. This second edition has new information on reaction limited models of dissolution, non binary biopharmaceutic classification system, time varying models, and interface models.

Автор: Rosenbaum Sara E.
Название: Basic Pharmacokinetics and Pharmacodynamics
ISBN: 1119143152 ISBN-13(EAN): 9781119143154
Издательство: Wiley
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Цена: 72810.00 T
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Описание: This book provides a comprehensive foundation for the contemporary application of pharmacokinetics and pharmacodynamics. The second edition updates and strengthens existing chapters and adds new topics to address current needs including physiologically based pharmacokinetic modeling, pharmacogenomics and predicting drug-drug interactions.

Автор: Alexander A. Vinks; Hartmut Derendorf; Johan W. Mo
Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics
ISBN: 1493950819 ISBN-13(EAN): 9781493950812
Издательство: Springer
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Цена: 158380.00 T
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Описание: Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. The book will be designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Автор: PL Madan
Название: Biopharmaceutics and Pharmacokinetics
ISBN: 9350909391 ISBN-13(EAN): 9789350909393
Издательство: JayPee Brothers India
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Цена: 57690.00 T
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Описание: Presents a major revision of a book originally published in 2000. This edition has been revised to incorporate new information that has become available since the publication of the first edition.

Автор: A. Yacobi; J.P. Skelly; Vinod P. Shah; L.Z. Benet
Название: Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development
ISBN: 1475715226 ISBN-13(EAN): 9781475715224
Издательство: Springer
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Цена: 104480.00 T
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Описание: Proceedings of a conference sponsored by the American Association of Pharmaceutical Scientists, the U.S. Food and Drug Administration, and the American Society for Clinical Pharmacology and Therapeutics, held in Arlington, Virginia, April 24-26, 1991

Автор: Shargel Leon
Название: Applied Biopharmaceutics & Pharmacokinetics, 7 ed.
ISBN: 0071830936 ISBN-13(EAN): 9780071830935
Издательство: McGraw-Hill
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Цена: 68630.00 T
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Описание: The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics-now fully updated

Автор: Alexander Vinks; Hartmut Derendorf; Johan Mouton (
Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics
ISBN: 0387756124 ISBN-13(EAN): 9780387756127
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Автор: Morrow Tyler
Название: Pharmacodynamics and Pharmacokinetics
ISBN: 1632417820 ISBN-13(EAN): 9781632417824
Издательство: Неизвестно
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Цена: 171660.00 T
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Автор: Tekade, Rakesh K.
Название: Biopharmaceutics And Pharmacokinetics Considerations
ISBN: 0128144254 ISBN-13(EAN): 9780128144251
Издательство: Elsevier Science
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Цена: 176290.00 T
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Описание:

Biopharmaceutics and Pharmacokinetics Considerations examines the history as well as the current state of the field within pharmaceutical sciences and concisely explains the history of biopharmaceutics and pharmacokinetics including key developments. It provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce as well as the movement of drugs within the body. This book provides a comprehensive examination suitable for researchers working in the pharmaceutical, cosmetics, biotechnology, and related industries as well as advanced students in these fields.

Автор: Kulkarni J. S., Pawar A. P., Manvi F. V.
Название: Biopharmaceutics and Pharmacokinetics
ISBN: 9389941903 ISBN-13(EAN): 9789389941906
Издательство: CBS India
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Цена: 22640.00 T
Наличие на складе: Нет в наличии.
Описание: The book covers various processes in biopharmaceutics including absorption, distribution, metabolism and elimination.

Автор: Michael W. Jann; Scott R. Penzak; Lawrence J. Cohe
Название: Applied Clinical Pharmacokinetics and Pharmacodynamics of Psychopharmacological Agents
ISBN: 3319802348 ISBN-13(EAN): 9783319802343
Издательство: Springer
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Цена: 111790.00 T
Наличие на складе: Невозможна поставка.
Описание: Thisbook is a comprehensive resource on psychotropic medications, detailing thelatest methods for defining their characteristics, their use in differentpatient populations, and drug-drug interactions; an important collection ofinformation forclinicians, students, researchers, and members of thepharmaceutical industry alike.Thefirst section provides the foundational principles of these drugs. Mathematicalmodeling of parameters that affect their entryto,and exit from, the centralnervous system (CNS) compartment are presented on an individual basis and thenapplied to target populations with specific disease states. Methods andcharacteristics that inform the transfer of these drugs from the laboratorybench to use in patient care are discussed, including imaging techniques,genetics and physiological barriers, such as the blood-brain barrier. The secondsection describes the characteristics of specific agents,nominally arrangedintodifferent therapeutic categories and with reference crossover use indifferent disease states. The pharmacologic characteristics of different drugformulations are explored in the context of their ability to improve patientadherence. The third section focuses on drug-drug interactions.Psychotropic medicationsfrom different categories are frequently prescribed together,or alongsidemedications used to treat comorbid conditions, and the information provided isdirectly relevant to the clinic, as a result.Theclinical application of pharmacokinetics and pharmacodynamics of CNS agents hasmade significant progress over the past 50 years and new information is reportedby numerous publications in psychiatry, neurology, and pharmacology.Ourunderstanding of the interrelationship between these medications, receptors,drug transporters, as well as techniques for measurement and monitoring theirinteractions,isfrequently updated. However, with information presented on ahost of different platforms, and in different formats, obtaining the fullpicture can be difficult. This title aims to collate this information into asingle source that can be easily interpreted and applied towards patient careby the clinical practitioner, and act as a reference for all others who have aninterest in psychopharmacological agents.