Virtual Screening And Drug Docking,59, Caballero, Julio

Автор: N.S. Parmar , Shiv Prakash
Название: Screening Methods in Pharmacology
ISBN: 1842653466 ISBN-13(EAN): 9781842653463
Издательство: Alpha Science
Цена: 40000.00 T
Наличие на складе: Есть
Описание: Provides a concise account of in vivo methods used in the pharmacological screening of important categories of clinically useful drugs. This book encompasses the basic principles of animal experimentation and current advances leading to the use of transgenic animals, combinatorial chemistry, pharmacogenomics, proteomics and array technology.

Автор: Takebayashi Toru, Landsiedel Robert, Gamo Masashi
Название: In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials
ISBN: 9811384355 ISBN-13(EAN): 9789811384356
Издательство: Springer
Цена: 93160.00 T
Наличие на складе: Невозможна поставка.
Описание: This book is intended for periodontal residents and practicing periodontists who wish to incorporate the principles of moderate sedation into daily practice. Comprehensive airway management and rescue skills are then documented in detail so that the patient may be properly managed in the event that the sedation progresses beyond the intended level.

Название: G Protein-Coupled Receptors
ISBN: 0367392372 ISBN-13(EAN): 9780367392376
Издательство: Taylor&Francis
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Цена: 65320.00 T
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Описание: With contributions from international experts in the fields of pharmacology, neuroscience, and biochemistry, this text provides an in-depth exploration of GPCRs. Coverage includes the screening of ligands for GPCRs, physiological and molecular characterizations of GPCRs, and structures of GPCRs and their ligands. The book explores current research issues in the post-genome era, particularly the identification of endogenous ligands that may lead to finding new hormones or neurotransmitters. It also discusses the determination of the tertiary structure of GPCRs, useful for understanding GPCR interactions and for the theoretical modeling of drugs.

Автор: Martins
Название: G Protein-Coupled Receptor Screening Assays
ISBN: 1071612239 ISBN-13(EAN): 9781071612231
Издательство: Springer
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Цена: 111790.00 T
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Описание: This fully updated edition targets not only those assays directly involved in the discovery of GPCR-active compounds but also those involved in cell-based experiments designed to study physiological responses. Whether coming from academia or industry, or being an experienced researcher or a newcomer to the field, the reader will find accessible methods and protocols that cover the latest developments on receptor purification, molecular biology, recombinant engineering, and analytical techniques that enable the real time monitoring of the complex GPCR signaling cascade and identification of potential drug targets. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and up-to-date, G Protein-Coupled Receptor Screening Assays: Methods and Protocols, Second Edition aims to provide the tools necessary to contribute to the advancement of GPCR research and discovery and ultimately lead to the availability of innovative and more efficient drugs.

Автор: Toru Takebayashi; Robert Landsiedel; Masashi Gamo
Название: In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials
ISBN: 9811384320 ISBN-13(EAN): 9789811384325
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Невозможна поставка.
Описание: This edited volume discusses the short-term inhalation study (STIS) and intratracheal administration, the two major in vivo inhalation-toxicity screening methods, which play an important role in efficient hazard evaluation. It also provides a general overview of the inhalation toxicity of nanomaterials and related issues. For each screening method, it provides up-to-date information on the test procedures, interpretation of the test results, useful applications, and related technologies. In view of the increasing variety of nanomaterials in practical use, the book offers a basis for building a framework for grouping and read-across assessments of nanomaterials.With contributions by academic and industrial experts, In vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials is a pragmatic reference resource for readers who are responsible for assessing the safety of nanomaterials in R&D and business, as well as researchers.

Автор: Zhu, Hao
Название: High-throughput screening assays in toxicology
ISBN: 1493981714 ISBN-13(EAN): 9781493981717
Издательство: Springer
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Цена: 88500.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book focuses on recently developed High Throughput Screening (HTS) assay protocols, many involved in the ToxCast and/or Tox21 initiatives, and the relevant HTS data analysis techniques. Divided into three sections, in vitro assays, in vivo assays, and computational techniques to analyze HTS data are all examined. Written for the highly successful Methods in Molecular Biology series, most chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, High Throughput Screening Assays in Toxicology serves as a valuable reference resource for translating new HTS techniques into standardized chemical toxicity assessment tools in order to advance modern toxicology research to a new era where HTS techniques can partially replace the prevailing animal models.

Автор: Michael Kahn
Название: High Throughput Screening for Novel Anti-Inflammatories
ISBN: 303489578X ISBN-13(EAN): 9783034895781
Издательство: Springer
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Цена: 139750.00 T
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Описание: Combinatorial chemistry in conjunction with High Throughput Screening (HTS) is revolutionizing the drug discovery process.

Автор: Dastmalchi Siavoush, Hamzeh-Mivehroud Maryam, Sokouti Babak
Название: Applied Case Studies and Solutions in Molecular Docking-Based Drug Design
ISBN: 1522503625 ISBN-13(EAN): 9781522503620
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 188100.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As the pharmaceutical industry continues to advance, new techniques in drug design are emerging. In order to deliver optimum care to patients, the development of innovative pharmacological techniques has become a widely studied topic.Applied Case Studies and Solutions in Molecular Docking-Based Drug Design is a pivotal reference source for the latest scholarly research on the progress of pharmaceutical design and computational approaches in the field of molecular docking. Highlighting innovative research perspectives and real-world applications, this book is ideally designed for professionals, researchers, practitioners, and medical chemists actively involved in computational chemistry and pharmaceutical sciences.

Автор: Dastmalchi Siavoush, Hamzeh-Mivehroud Maryam, Sokouti Babak
Название: Methods and Algorithms for Molecular Docking-Based Drug Design and Discovery
ISBN: 1522501150 ISBN-13(EAN): 9781522501152
Издательство: Mare Nostrum (Eurospan)
Рейтинг:
Цена: 267520.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: As the pharmaceutical industry continues to advance, new techniques in drug design are emerging. In order to deliver optimal care to patients, the development of innovative pharmacological techniques has become a widely studied topic.The Handbook of Research on Molecular Docking-Based Drug Design and Discovery investigates the evolution of pharmaceutical design and computational approaches in the field of molecular docking. Highlighting theoretical backgrounds and emergent research in the area of computer-assisted drug design, this publication is a pivotal source for professionals, researchers, medical chemists, pharmaceutical experts, and students interested in innovative practices and findings within the fields of computational chemistry and pharmaceutical sciences.

Автор: S. Mohane Coumar
Название: Molecular docking for computer-aided drug design
ISBN: 012822312X ISBN-13(EAN): 9780128223123
Издательство: Elsevier Science
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Цена: 107740.00 T
Наличие на складе: Нет в наличии.
Описание: Collins Explore English is a 6-level course which provides full coverage of the Cambridge Primary English as a Second Language curriculum framework (0057) from 2020. With a magazine-style Student`s Resource Book, comprehensive Student`s Coursebook, and supportive Teacher`s Guide, it offers clear progression within and across levels.

Автор: Walter Filgueira de Azevedo Jr.
Название: Docking Screens for Drug Discovery
ISBN: 1493997513 ISBN-13(EAN): 9781493997510
Издательство: Springer
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Цена: 111790.00 T
Наличие на складе: Поставка под заказ.
Описание: This book focuses on recent developments in docking simulations for target proteins with chapters on specific techniques or applications for docking simulations, including the major docking programs.

Автор: Walter Filgueira de Azevedo Jr.
Название: Docking Screens for Drug Discovery
ISBN: 1493997548 ISBN-13(EAN): 9781493997541
Издательство: Springer
Рейтинг:
Цена: 111790.00 T
Наличие на складе: Поставка под заказ.