Название: G Protein-Coupled Receptors ISBN: 0367455609 ISBN-13(EAN): 9780367455606 Издательство: Taylor&Francis Рейтинг: Цена: 63280.00 T Наличие на складе: Невозможна поставка. Описание: Covering recently developed methods in membrane-bound receptors, this book emphasizes receptor structure and function. This book provides a broad base of knowledge. Topics include the regulation of receptors; phosphorylation of G-protein-coupled receptors and ion channel receptors; desensitization studies using electrophysiological or confocal micr
Название: G Protein-Coupled Receptors in Drug Discovery ISBN: 0367392518 ISBN-13(EAN): 9780367392512 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Нет в наличии. Описание:
The broad range of G protein-coupled receptors (GPCRs) encompasses all areas of modern medicine and have an enormous impact on the process of drug development. Using disease-oriented methods to cover everything from screening to expression and crystallization, G Protein-Coupled Receptors in Drug Discovery describes the physiological roles of GPCRs and their involvement in various human diseases.
The book presents current approaches in drug discovery that include target selection, establishment of screening and functional assays. It also covers recombinant GPCR expression for drug screening and structural biology, different methods for structural characterization of GPCRs, and the importance of bioinformatics. The book has been carefully edited to avoid overlapping information, some duplication has been intentionally permitted so that each chapter can function as an independent unit. Providing in-depth discussions on structure and dynamics of GPCRs, this book outlines the importance of the GPCRs to drug discovery in general and drug targets specifically.
Daniel E. Levy, editor of the Drug Discovery Series, is the founder of DEL BioPharma, a consulting service for drug discovery programs. He also maintains a blog that explores organic chemistry.
Автор: Shukla, Arun K. Название: G Protein-Coupled Receptors, Part B, 2nd Edition ISBN: 0128133198 ISBN-13(EAN): 9780128133194 Издательство: Elsevier Science Рейтинг: Цена: 156080.00 T Наличие на складе: Поставка под заказ. Описание:
G Protein Coupled Receptors, Second Edition, Volume 143, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. It contains a wide array of topics about the G protein coupled receptors, as well as updates of chapters from the first edition.
Название: G Protein-Coupled Receptors: From Structure to Function ISBN: 1849731837 ISBN-13(EAN): 9781849731836 Издательство: Royal Society of Chemistry Рейтинг: Цена: 239350.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book considers the relationship between structure and function in G protein-coupled receptors (GPCRs) and the implications for drug design.
Автор: Bruce G. Allen; Terence E. H?bert Название: Nuclear G-Protein Coupled Receptors ISBN: 1493955462 ISBN-13(EAN): 9781493955466 Издательство: Springer Рейтинг: Цена: 88500.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Nuclear G-Protein Coupled Receptors: Methods and Protocols is a compilation of a number of conceptual and methodological aspects important for the validation and characterization of intacrine signaling systems.
From Structure to Clinical Development: Allosteric Modulation of G Protein-Coupled Receptors, Volume 88, the latest release in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this updated edition include Targeting muscarinic M1 receptor in neurodegeneration, Photo‐switchable allosteric ligands, Computational approaches for the design of mGlu receptor allosteric modulators, Allosteric modulation of GLP‐1 receptor in metabolic disorders, Group II mGluR roles in the nervous system and their roles in addiction, RAMPs as allosteric modulators of Class B GPCRs, Structure‐based discovery and development of mGlu5 NAMs, and much more.
Автор: Marta Filizola Название: G Protein-Coupled Receptors - Modeling and Simulation ISBN: 9402402586 ISBN-13(EAN): 9789402402582 Издательство: Springer Рейтинг: Цена: 130590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses.
Автор: Bruce G. Allen; Terence E. H?bert Название: Nuclear G-Protein Coupled Receptors ISBN: 1493917544 ISBN-13(EAN): 9781493917549 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Nuclear G-Protein Coupled Receptors: Methods and Protocols is a compilation of a number of conceptual and methodological aspects important for the validation and characterization of intacrine signaling systems.
Автор: Marta Filizola Название: G Protein-Coupled Receptors - Modeling and Simulation ISBN: 9400774222 ISBN-13(EAN): 9789400774223 Издательство: Springer Рейтинг: Цена: 148020.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: G protein-coupled receptors (GPCRs) are heptahelical transmembrane receptors that convert extra-cellular stimuli into intra-cellular signaling, and ultimately into biological responses.
Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scientific importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine β-synthase, and Oligomerization of Porphobilinogen Synthase.
Автор: Arun K. Shukla Название: G Protein-Coupled Receptors: Signaling, Trafficking and Regulatio ISBN: 0128035951 ISBN-13(EAN): 9780128035955 Издательство: Elsevier Science Рейтинг: Цена: 141480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
"G-Protein-Coupled Receptors: Signaling, Trafficking, and Regulation," a new volume in the "Methods in Cell Biology" series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in G-Protein-Coupled Receptors, and includes sections on such topics signaling, trafficking and regulation. Covers the increasingly appreciated cell biology field of G-protein-coupled receptorsIncludes both established and new technologiesContributed by experts in the fieldCovers topics such as signaling, trafficking, and regulation
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