Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics, Panos Macheras; Athanassios Iliadis

Автор: Macheras Panos, Iliadis Athanassios
Название: Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics / Homogeneous and Heterogeneous Approaches
ISBN: 0387281789 ISBN-13(EAN): 9780387281780
Издательство: Springer
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Цена: 55850.00 T
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Описание: The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. The state of the art in Biopharmaceutics, Pharmacokinetics, and Pharmacodynamics Modeling is presented in this book. It shows how advanced physical and mathematical methods can expand classical models in order to cover heterogeneous drug-biological processes and therapeutic effects in the body. The book is divided into four parts; the first deals with the fundamental principles of fractals, diffusion and nonlinear dynamics; the second with drug dissolution, release, and absorption; the third with empirical, compartmental, and stochastic pharmacokinetic models, and the fourth mainly with nonclassical aspects of pharmacodynamics. The classical models that have relevance and application to these sciences are also considered throughout. Many examples are used to illustrate the intrinsic complexity of drug administration related phenomena in the human, justifying the use of advanced modeling methods. www.springeronline.com

Автор: Alexander Vinks; Hartmut Derendorf; Johan Mouton (
Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics
ISBN: 0387756124 ISBN-13(EAN): 9780387756127
Издательство: Springer
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Цена: 158380.00 T
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Описание: The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Автор: Burton
Название: Applied Pharmacokinetics and Pharmacodynamics
ISBN: 0781744318 ISBN-13(EAN): 9780781744317
Издательство: Lippincott Williams & Wilkins
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Цена: 51480.00 T
Наличие на складе: Невозможна поставка.
Описание: "The definitive advanced-level clinical pharmacokinetics text is now in its Fourth Edition, with new emphasis on the relationship between pharmacokinetics and pharmacodynamics. Written by 70 leading researchers and practitioners, this book is a rigorous yet practical text on the application of pharmacokinetic methods, pharmacodynamic principles, and pharmacotherapeutic data for optimal, individualized drug therapy.

Автор: Tozer
Название: Introduction to Pharmacokinetics and Pharmacodynamics: The Quantitative Basis of Drug Therapy
ISBN: 0781751497 ISBN-13(EAN): 9780781751490
Издательство: Lippincott Williams & Wilkins
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Цена: 49190.00 T
Наличие на складе: Поставка под заказ.
Описание: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.

Автор: A. Yacobi; J.P. Skelly; Vinod P. Shah; L.Z. Benet
Название: Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development
ISBN: 1475715226 ISBN-13(EAN): 9781475715224
Издательство: Springer
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Цена: 104480.00 T
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Описание: Proceedings of a conference sponsored by the American Association of Pharmaceutical Scientists, the U.S. Food and Drug Administration, and the American Society for Clinical Pharmacology and Therapeutics, held in Arlington, Virginia, April 24-26, 1991

Автор: Shargel
Название: Applied Biopharmaceutics & Pharmacokinetics
ISBN: 0071240055 ISBN-13(EAN): 9780071240055
Издательство: McGraw-Hill
Цена: 28590.00 T
Наличие на складе: Поставка под заказ.
Описание: The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.

Автор: Nightingale Charles H
Название: Antimicrobial Pharmacodynamics
ISBN: 0824729250 ISBN-13(EAN): 9780824729257
Издательство: Taylor&Francis
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Цена: 224570.00 T
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Описание: Antimicrobial Pharmacodynamics in Theory and Clinical Practice

Автор: Shargel Leon
Название: Applied Biopharmaceutics & Pharmacokinetics, 7 ed.
ISBN: 0071830936 ISBN-13(EAN): 9780071830935
Издательство: McGraw-Hill
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Цена: 68630.00 T
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Описание: The landmark textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics-now fully updated

Автор: Rosenbaum Sara E.
Название: Basic Pharmacokinetics and Pharmacodynamics
ISBN: 1119143152 ISBN-13(EAN): 9781119143154
Издательство: Wiley
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Цена: 72810.00 T
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Описание: This book provides a comprehensive foundation for the contemporary application of pharmacokinetics and pharmacodynamics. The second edition updates and strengthens existing chapters and adds new topics to address current needs including physiologically based pharmacokinetic modeling, pharmacogenomics and predicting drug-drug interactions.

Автор: Younggil Kwon
Название: Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for Industrial Scientists
ISBN: 147578693X ISBN-13(EAN): 9781475786934
Издательство: Springer
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Цена: 149060.00 T
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Описание: In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization.

Автор: Alexander A. Vinks; Hartmut Derendorf; Johan W. Mo
Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics
ISBN: 1493950819 ISBN-13(EAN): 9781493950812
Издательство: Springer
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Цена: 158380.00 T
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Описание: Over the past decade, significant progress has been made in the theory and applications of pharmacodynamics of antimicrobial agents. On the basis of pharmacokinetic-pharmacodynamic modeling concepts it has become possible to describe and predict the time course of antimicrobial effects under normal and pathophysiological conditions. The study of pharmacokinetic-pharmacodynamic relationships can be of considerable value in understanding drug action, defining optimal dosing regimens, and in making predictions under new or changing pre-clinical and clinical circumstances. Not surprisingly, pharmacokinetic-pharmacodynamic modeling concepts are increasingly applied in both basic and clinical research as well as in drug development. The book will be designed as a reference on the application of pharmacokinetic-pharmacodynamic principles for the optimization of antimicrobial therapy, namely pharmacotherapy, and infectious diseases. The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Автор: Shargel
Название: Applied Biopharmaceutics & Pharmacokinetics.2004
ISBN: 0071375503 ISBN-13(EAN): 9780071375504
Издательство: McGraw-Hill
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Цена: 62910.00 T
Наличие на складе: Невозможна поставка.
Описание: This pharmacy textbook examines how the physicochemical properties of a drug, the dosage form in which the drug is given, and the route of administration influence the rate and extent of systemic drug absorption. The authors model the pharmacokinetics of drugs following both intravenous drug administration and extravascular delivery, and consider t