Perioperative Inflammation as Triggering Origin of Metastasis Development, Retsky Michael W., Demicheli Romano

Автор: Steven A. Vasilev, Scott E. Lentz, Allison E. Axte
Название: Gynecologic Oncology: Evidence-Based Perioperative and Supportive Care 2E
ISBN: 0470083409 ISBN-13(EAN): 9780470083406
Издательство: Wiley
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Цена: 99570.00 T
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Описание: This is the only reference and textbook of its kind to cover perioperative and supportive care in gynecologic oncology within the framework of evidence-based medicine.

Название: Metastasis
ISBN: 1621823245 ISBN-13(EAN): 9781621823247
Издательство: Неизвестно
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Цена: 49140.00 T
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Описание: Nearly all types of cancer have the ability to metastasize, or spread from one organ or tissue in the body to another. Metastatic disease is responsible for the majority of cancer deaths and, therefore, is a critical area of research. Work to better understand the metastatic cascade-how cells
detach from a primary tumor, migrate through the body, and seed secondary tumors at distant locations-will lead to improved treatment options for patients with cancer.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers the recent progress that has been made in understanding the molecular mechanisms underlying metastasis and how this knowledge is paving the way for new therapeutic targets. The
contributors discuss progress in defining mutations that might be driving metastasis, the formation of a premetastatic niche and how it enhances the establishment of a secondary tumor, and how changes that occur during aging increase the metastatic capacity of tumor cells. They also consider the
selection and colonization of common target organs (e.g., brain, liver, and bones) during metastasis and the roles of immune cells and extracellular vesicles at different steps of the metastatic cascade. Cellular plasticity-including evidence for metastatic stem cells and the role of tumor cell
dormancy in recurrent metastasis-is also covered.

In addition, the authors describe the development of in vivo models and techniques for studying metastasis, methods for monitoring tumor progression and metastatic spread (e.g., intravital microscopy and liquid biopsy), and immunotherapies that can potentially target cancer metastasis. This volume
is therefore a vital reference for all cancer biologists and clinician-scientists concerned with defeating cancer.

Автор: Kok-Yang Tan
Название: Transdisciplinary Perioperative Care in Colorectal Surgery
ISBN: 3662440199 ISBN-13(EAN): 9783662440193
Издательство: Springer
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Цена: 102480.00 T
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Описание: Subsequent chapters focus on a range of issues associated with surgical and perioperative care in patients undergoing colorectal surgery, with emphasis on how the multiple facets of care can be integrated through a transdisciplinary approach.

Автор: U. Metzger; F. Largiader; H.-J. Senn
Название: Perioperative Chemotherapy
ISBN: 364282434X ISBN-13(EAN): 9783642824340
Издательство: Springer
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Цена: 121110.00 T
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Описание: Proceedings of an International Symposium, 17-18 March 1983, Zurich University Hospital

Автор: Maru
Название: Inflammation and Metastasis
ISBN: 4431567569 ISBN-13(EAN): 9784431567561
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Нет в наличии.
Описание: This book provides the latest information on cancer metastasis from the standpoint of inflammation, especially innate immune reactions caused by endogenous mediators but not exogenous pathogens, with ideas on how to understand the complicated mechanisms of metastasis as well as to interpret therapeutic targets. The book includes the topic of the emerging roles of endogenous TLR4 ligands whose functions are shared intriguingly by metastasis and auto-inflammatory diseases such as rheumatoid arthritis. For example, most cancer therapies established so far are effective initially. However, they eventually face the great obstacles of drug resistance, immune evasion, and metastatic progression. One of the endogenous TLR4 ligands is thought to contribute to all three processes. The most important features of the book are to explain a concept of homeostatic inflammation, disturbance of which in the lungs gives rise to the establishment of a pre-metastatic pulmonary microenvironment based on primary tumor-mediated hijacking of the innate immune defense system against respiratory infection. In addition, structure-based thinking is another important feature of this book. It is proposed that inflammation forms a functional triangle with angiogenesis and coagulation, in the center of which cancer is located. Given the proposal of precision medicine by President Obama in the United States in 2015 and the recent success of immune-modulator-based therapy, this book will appeal to researchers in a variety of fields with the title of the book connecting the worst disease (metastasis) and the most fundamental event (inflammation) that is common to many diseases.

Автор: Maru Yoshiro
Название: Inflammation and Metastasis
ISBN: 9811617562 ISBN-13(EAN): 9789811617560
Издательство: Springer
Цена: 186330.00 T
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Описание: This book, now in a thoroughly revised and updated second edition, provides the latest information on cancer metastasis from the perspective of inflammation and presents new ideas on the complicated mechanisms of metastasis and potential therapeutic targets.

Автор: Kurt Hellmann; P. Hilgard; Suzanne A. Eccles
Название: Metastasis
ISBN: 940098927X ISBN-13(EAN): 9789400989276
Издательство: Springer
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Цена: 46570.00 T
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Описание: The Metastasis Group of the European Organization for Research on Treatment of Cancer (EORTC) held an International Meeting at the Royal Institution in London on April 2lst-23rd, 1980.

Автор: Abdel-Majid Khatib
Название: Regulation of Carcinogenesis, Angiogenesis and Metastasis by the Proprotein Convertases (PC`s)
ISBN: 9401780900 ISBN-13(EAN): 9789401780902
Издательство: Springer
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Цена: 149060.00 T
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Описание: Convertases are widely expressed activating enzymes involved in various physiological and pathological processes. The purpose of this book is to provide detailed and updated information on the role of these molecules in cancer. This book is the first to summarize current knowledge about the importance of protein precursors maturation by the convertases in tumor progression, angiogenesis and metastasis. In each chapter, the importance of the convertases in the activation of various cancer-related molecules including growth factors, adhesion molecules and proteases is discussed. Also this book covers the role of some convertases in the clinical setting. The book will be of interest to basic researchers as well as clinicians. It will also interest those working in the cancer research area and the pharmaceutical industry, who are looking for new strategies in cancer therapy. Finally, this book is also a useful reference for researchers and clinicians pursuing research on growth factors, adhesion molecules, proteases and their implications in the processes of tumor progression, angiogenesis and metastasis.

Автор: Gurmit Singh; William Orr
Название: Bone Metastasis and Molecular Mechanisms
ISBN: 9048165636 ISBN-13(EAN): 9789048165636
Издательство: Springer
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Цена: 213360.00 T
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Описание: Patients with advanced breast or prostate cancers usually develop bone metastases. The principal complications resulting from metastatic bone disease are pain, spinal cord compression, pathologic fractures and bone marrow suppression.

Автор: Chris Maxwell; Cal Roskelley
Название: Genomic Instability and Cancer Metastasis
ISBN: 3319352954 ISBN-13(EAN): 9783319352954
Издательство: Springer
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Цена: 130590.00 T
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Описание: Metastasis is the primary cause of mortality associated with cancer, and tumor genomic heterogeneity is a likely source for the cells that support cancer progression, resistance to therapy, and disease relapse.

Автор: Domenico Ribatti
Название: The Chick Embryo Chorioallantoic Membrane in the Study of Angiogenesis and Metastasis
ISBN: 9400791577 ISBN-13(EAN): 9789400791572
Издательство: Springer
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Цена: 104480.00 T
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Описание: 1. Introduction 2. Chorioallantoic membrane and its embryological origin 2.1. Morphology of chorioallantoic membrane blood and lymphatic vessels 2.2. A single blood sinus or a capillary plexus beneath the chorionic epithelium? 2.3. The chorioallantoic membrane vascular growth 3. Use of chorioallantoic membrane in the study of angiogenic molecules 3.1. Role of FGF-2 in chorioallantoic membrane vascularization 4. Use of chorioallantoic membrane in the study of antiangiogenic molecules 5. Use of chorioallantoic membranes in the study of tumor angiogenesis 5.1. Angiogenesis and antiangiogenesis in multiple myeloma 5.2. Angiogenesis and antiangiogenesis in human neuroblastoma 6. Use of chorioallantoic membrane in the study of tumor metastasis 6.1. Spontaneous metastasis models. 6.2. Experimental metastasis studies. 7. Other applications 7.1. In ovo and ex ovo methods 7.2. Use of chorioallantoic membrane in the study of tumor lymphangiogenesis 8. Different morphological techniques that can be used to study vascularization of the CAM and the genes involved. 9. Methods of quantifying the angiogenic response 10. Limitations of the chorioallantoic membrane assay 11. Other classical in vivo assays in comparison (advantages, disadvantages and limitations) with the chorioallantoic membrane 12. Concluding remarks Acknowledgments References

Автор: Marie-Odile Parat
Название: Morphine and Metastasis
ISBN: 9400792964 ISBN-13(EAN): 9789400792968
Издательство: Springer
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Цена: 104480.00 T
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Описание: This book explores the effect of morphine and other opioids on tumor growth and metastasis. Discusses which type of post surgical pain management can minimize the risk of recurrence or metastasis, animal research on the effects of morphine on tumors and more.