Drug Resistance in Bacteria, Fungi, Malaria, and Cancer, Arora Gunjan, Sajid Andaleeb, Kalia Vipin Chandra
Автор: Henry M. Staines; Sanjeev Krishna Название: Treatment and Prevention of Malaria ISBN: 3034808089 ISBN-13(EAN): 9783034808088 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Starting with an overview of the disease and its current political, financial and technical context, this Milestones in Drug Therapy volume describes the history, chemistry, mechanisms of action and resistance, preclinical and clinical use, pharmacokinetics and safety and tolerability of the current range of antimalarial drugs.
Автор: Gunjan Arora; Andaleeb Sajid; Vipin Chandra Kalia Название: Drug Resistance in Bacteria, Fungi, Malaria, and Cancer ISBN: 3319486829 ISBN-13(EAN): 9783319486826 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is a compilation of past and recent knowledge in the field of emerging drug resistance. The book covers major aspects of drug resistance in bacteria, fungi, malaria, and cancer.Human survival on earth is constantly threatened by disease and syndrome.
Medicinal Chemistry Approaches to Malaria and Other Tropical Disease, Volume 53 in the Annual Reports in Medicinal Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.
4.Breast Cancer: Current perspectives on the disease status
5. Role of Autophagy in Breast Cancer Development and Progression: Opposite Sides of the Same Coin
6. Breast Cancer Heterogeneity in Primary and Metastatic Disease
7. Bone Metastasis of Breast Cancer
8. Therapeutic Options for Metastatic Breast Cancer
9.Chemotherapy and inflammatory cytokine signalling in cancer cells and the tumour microenvironment
10. Current Updates on Trastuzumab Resistance in HER2 overexpressing Breast Cancers
11.Non-coding RNAs as mediators of tamoxifen resistance in breast cancers
12. TRAIL Mediated Signaling in Breast Cancer: Awakening Guardian Angel to Induce Apoptosis and Overcome Drug Resistance
13. Current state of platinum complexes for the treatment of advanced and drug-resistant breast cancers
14.Targeting of JAK-STAT Signaling in Breast Cancer: Therapeutic Strategies to Overcome Drug Resistance
15. Role of mTORC1 and mTORC2 in Breast Cancer: Therapeutic Targeting of mTOR and its Partners to Overcome Metastasis and Drug Resistance
16. Epigenetics of Breast Cancer: Clinical Status of Epi-Drugs and Phytochemicals
17. Targeting CSC in a most aggressive subtype of breast cancer TNBC
18. Cross-roads to drug resistance and metastasis in breast cancer: miRNAs regulatory function and biomarker capability
19. NEDD4 Family of E3 Ubiquitin Ligases in Breast Cancer: Spotlight on SMURFs, WWPs and NEDD4
20. Emerging Novel Therapeutics in Triple-Negative Breast Cancer
21.Breast Cancer: Proteolysis and Migration
22.Current and emerging 3D models to study breast cancer
Автор: Robert F. Ozols Название: Drug Resistance in Cancer Therapy ISBN: 0792302443 ISBN-13(EAN): 9780792302445 Издательство: Springer Рейтинг: Цена: 213360.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Where do you begin to look for a recent, authoritative article on the diagnosis or management of a particular malignancy? The few general oncology textbooks are generally out of date. Single papers in specialized journals are informative but seldom comprehensive; these are more often preliminary reports on a very limited number of patients. Certain general journals frequently publish good in-depth reviews of cancer topics, and published symposium lectures are often the best overviews available. Unfor- tunately, these reviews and supplements appear sporadically, and the reader can never be sure when a topic of special interest will be covered. Cancer Treatment and Research is a series of authoritative volumes that aim to meet this need. It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, easily available on a single library shelf or by a single personal subscription. We have approached the problem in the following fashion: first, by dividing the oncology literature into specific subdivisions such as lung can- cer, genitourinary cancer, and pediatric oncology; second, by asking emi- nent authorities in each of these areas to edit a volume on the specific topic on an annual or biannual basis. Each topic and tumor type is covered in a volume appearing frequently and predictably, discussing current diagnosis, staging, markers, all forms of treatment modalities, basic biology, and more.
Автор: Susan E. Bates; Kapil Mehta; Zahid H. Siddik Название: Drug Resistance in Cancer Cells ISBN: 1441927948 ISBN-13(EAN): 9781441927941 Издательство: Springer Рейтинг: Цена: 139310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The inability of cancer drugs to destroy metastatic tumors is the main reason cancer therapy fails. This comprehensive text offers current knowledge on genetic and epigenetic alterations that contribute to the development of drug resistance in cancer cells.
Автор: Ahmad Aamir Название: Breast Cancer Metastasis and Drug Resistance: Challenges and Progress ISBN: 303020300X ISBN-13(EAN): 9783030203009 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.
Автор: Sosnik, Alejandro Название: Drug Efflux Pumps In Cancer Resistance Pathways: From Molecular Recognition And Characterization To Possible Inhibition Strategies In Chemotherapy,7 ISBN: 0128164344 ISBN-13(EAN): 9780128164341 Издательство: Elsevier Science Рейтинг: Цена: 151590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Besides the ITIL(R) 4 Foundation Courseware - English (ISBN: 9789401803939) publication you are advised to obtain the publication ITIL(R) 4 - A Pocket Guide (ISBN: 978 94 018 0439 4).The course is designed as an introduction to ITIL 4 and enables you to understand a new way to look at IT Service Management through a Service Value System (SVS). ITIL 4 provides an end-to-end picture of what means to contribute to business value, and also integrates concepts from models such as Lean IT, Agile and DevOps.This course is for those who are involved in the delivery of IT services and need an understanding of best practice in IT Service Management. Student must pass a 60 minute, 40 question closed book multiple choice, examination with a passing score of 65% in order to receive this certification. You can write the exam at any time and at any place after the course. The test is done via your own computer proctored via webcam.Candidates wishing to be trained and pass the exam for this qualification would be recommended to have a general awareness of IT and appreciation of their own business environment.You`ll learn:¢ Understand the key concepts of service management¢ Understand how the ITIL guiding principles can help an organization adopt and adapt service management¢ Understand the four dimensions of service management¢ Understand the purpose and components of the ITIL service value system¢ Understand the activities of the service value chain, and how they interconnect¢ Know the purpose and key terms of 18 ITIL practices¢ Understand 7 ITIL practices
Автор: Jose Rueff; Ant?nio Sebasti?o Rodrigues Название: Cancer Drug Resistance ISBN: 1493980270 ISBN-13(EAN): 9781493980277 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
1. Cancer Drug Resistance: A Brief Overview from a Genetic Viewpoint Josй Rueff and Antуnio S. Rodrigues 2. Classical and Targeted Anti-Cancer Drugs: An Appraisal of Mechanisms of Multidrug Resistance Bruce C. Baguley 3. In Vitro Methods for Studying the Mechanisms of Resistance to DNA Damaging Therapeutic Drugs Pasarat Khongkow, Anna
K. Middleton, Jocelyn P.-M. Wong, - Navrohit K. Kandola, Mesayamas Kongsema, Gabriela Nestal de Moraes, Ana R. Gomes, and Eric W.-F. Lam 4. In Vitro Approaches to Study Regulation of Hepatic Cytochrome P450 (CYP) 3A Expression by Paclitaxel and Rifampicin Romi Ghose, Pankajini Mallick, Guncha Taneja, Chun Chu, and Bhagavatula Moorthy 5. Uptake and Permeability Studies to Delineate the Role of Efflux Transporters Ramya Krishna Vadlapatla, Dhananjay Pal, and Ashim K. Mitra 6. Dynamics of Expression of Drug Transporters: Methods for Appraisal Marta Gromicho, Josй Rueff, and Antуnio S. Rodrigues 7. Fluorimetric Methods for Analysis of Permeability, Drug Transport Kinetics, and Inhibition of the ABCB1 Membrane Transporter Ana Armada, Cйlia Martins, Gabriella Spengler, Joseph Molnar, Leonard Amaral, Antуnio S. Rodrigues, and Miguel Viveiros 8. Resistance to Targeted Therapies in Breast Cancer Sofia Braga 9. MicroRNAs and Cancer Drug Resistance Bruno Costa Gomes, Josй Rueff, and Antуnio S. Rodrigues 10. The Role of MicroRNAs in Resistance to Current Pancreatic Cancer Treatment: Translational Studies and Basic Protocols for Extraction and PCR Analysis Ingrid Garajovб, Tessa Y.S. Le Large, Elisa Giovannetti, Geert Kazemier, Guido Biasco, and Godefridus J. Peters 11. Methods for Studying MicroRNAs Expression and Their Targets in Formalin-Fixed, Paraffin-Embedded (FFPE) Breast Cancer Tissues Bruno Costa Gomes, Bruno Santos, Josй Rueff, and Antуnio S. Rodrigues 12. The Regulatory Role of Long Non-Coding RNAs in Cancer Drug Resistance Marjan E. Askarian-Amiri, Euphemia Leung, Graeme Finlay, and Bruce C. Baguley 13. Cancer Exosomes as Mediators of Drug Resistance Maria do Rosбrio Andrй, Ana Pedro, and David Lyden 14. Isolation and Characterization of Cancer Stem Cells from Primary Head and Neck Squamous Cell Carcinoma Tumors Hong S. Kim, Alexander T. Pearson, and Jacques E. Nцr 15. Clinical and Molecular Methods in Drug Development: Neoadjuvant Systemic Therapy in Breast Cancer as a Model Sofia Braga 16. Proteomics in the Assessment of the Therapeutic Response of Anti-Neoplastic Drugs: Strategies and Practical Applications Vukosava Milic Torres, Lazar Popovic, Fбtima Vaz, and Deborah Penque 17. Managing Drug Resistance in Cancer: Role of Cancer Informatics Ankur Gautam, Kumardeep Chaudhary, Rahul Kumar, Sudheer Gupta, Harinder Singh, and Gajendra P.S. Raghava
Автор: Martin Clynes Название: Multiple Drug Resistance in Cancer 2 ISBN: 0792352726 ISBN-13(EAN): 9780792352723 Издательство: Springer Рейтинг: Цена: 231990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Resistance to chemotherapy, and especially multi-drug resistance, represents a significant barrier to the successful treatment of cancer. This volume brings together a wide range of reviews on different aspects of our knowledge of drug-resistance mechanisms. It includes coverage of topics such as: DNA repair, topoisomerases and cell cycle control.
Автор: Pinedo Название: Drug Resistance in the Treatment of Cancer ISBN: 0521473217 ISBN-13(EAN): 9780521473217 Издательство: Cambridge Academ Рейтинг: Цена: 174240.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Reviews the mechanisms and clinical implications of drug resistance in cancer, considered to be the most significant obstacle to the cure of cancer today. Topics covered include multiple drug resistance and its reversal, topoisomerase drugs, apoptosis, dose intensity and escalation, gene therapy and haematopoietic support.
Автор: Teicher, Beverly A. (Ed.) Название: Cancer Drug Resistance ISBN: 1617376221 ISBN-13(EAN): 9781617376221 Издательство: Springer Рейтинг: Цена: 241310.00 T Наличие на складе: Поставка под заказ. Описание: Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it.
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