Breast Cancer Metastasis and Drug Resistance: Challenges and Progress, Ahmad Aamir

Автор: Ahmad Aamir
Название: Breast Cancer Metastasis and Drug Resistance: Challenges and Progress
ISBN: 303020300X ISBN-13(EAN): 9783030203009
Издательство: Springer
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Цена: 130430.00 T
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Описание: Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

Название: Metastasis
ISBN: 1621823245 ISBN-13(EAN): 9781621823247
Издательство: Неизвестно
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Цена: 49140.00 T
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Описание: Nearly all types of cancer have the ability to metastasize, or spread from one organ or tissue in the body to another. Metastatic disease is responsible for the majority of cancer deaths and, therefore, is a critical area of research. Work to better understand the metastatic cascade-how cells
detach from a primary tumor, migrate through the body, and seed secondary tumors at distant locations-will lead to improved treatment options for patients with cancer.

Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine covers the recent progress that has been made in understanding the molecular mechanisms underlying metastasis and how this knowledge is paving the way for new therapeutic targets. The
contributors discuss progress in defining mutations that might be driving metastasis, the formation of a premetastatic niche and how it enhances the establishment of a secondary tumor, and how changes that occur during aging increase the metastatic capacity of tumor cells. They also consider the
selection and colonization of common target organs (e.g., brain, liver, and bones) during metastasis and the roles of immune cells and extracellular vesicles at different steps of the metastatic cascade. Cellular plasticity-including evidence for metastatic stem cells and the role of tumor cell
dormancy in recurrent metastasis-is also covered.

In addition, the authors describe the development of in vivo models and techniques for studying metastasis, methods for monitoring tumor progression and metastatic spread (e.g., intravital microscopy and liquid biopsy), and immunotherapies that can potentially target cancer metastasis. This volume
is therefore a vital reference for all cancer biologists and clinician-scientists concerned with defeating cancer.

Автор: Lekin Sandra
Название: Breast Cancer: Gene Regulation and Metastasis
ISBN: 1632410664 ISBN-13(EAN): 9781632410665
Издательство: Неизвестно
Цена: 134050.00 T
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Описание: Commonly known to occur in women, breast cancer can also occur in men. Cancer is the principal reason of death in the majority of countries and it results in enormous financial, societal and mental burden. Breast cancer is the most diagnosed kind of cance

Автор: Martin Tracey A
Название: Tight Junctions in Cancer Metastasis
ISBN: 9400760272 ISBN-13(EAN): 9789400760271
Издательство: Springer
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Цена: 174150.00 T
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Описание: This book summarizes current knowledge of tight junctions and their role in cancer and cancer metastasis. Coverage includes fundamental changes in tight junctions in the process of cancer development and the importance of cellular structure in drug therapy.

Автор: Ahmad Aamir
Название: Introduction to Cancer Metastasis
ISBN: 0128040033 ISBN-13(EAN): 9780128040034
Издательство: Elsevier Science
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Цена: 135870.00 T
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Описание: Introduction to Cancer Metastasis provides, in one place, an overview of organ-specific cancer metastasis and the most common sites of cancer metastasis. Through specific chapters on individual primary cancers, their metastasis, and chapters on common metastatic sites, this volume comprehensively informs readers about the broader knowledge base in cancer metastasis. The process of metastasis is particularly responsible for making cancer so lethal. This volume explores both metastasis from sites of origin and common metastatic sites, thus increasing understanding of both perspectives.

Автор: Wen G. Jiang
Название: Electric Cell-Substrate Impedance Sensing and Cancer Metastasis
ISBN: 9400793804 ISBN-13(EAN): 9789400793804
Издательство: Springer
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Цена: 148010.00 T
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Описание: This book reviews the fundamentals of electric cell-substrate impedance sensing, and recent progress which permits high-throughput automated analyses. Coverage focuses on applications in cell based investigations, particularly in the area of cancer biology.

Автор: Wen G. Jiang; R.E. Mansel
Название: Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention
ISBN: 9401740712 ISBN-13(EAN): 9789401740715
Издательство: Springer
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Цена: 139750.00 T
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Описание: This book covers the molecular and cellular aspects of cancer metastasis, and discusses the clinical aspect of micro- and macro-metastases, which result in the death of the majority of patients with cancer.

Автор: James P. Karr; Hidetoshi Yamanaka
Название: Prostate Cancer and Bone Metastasis
ISBN: 1461365015 ISBN-13(EAN): 9781461365013
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
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Описание: The biology of solid tumor metastasis has been the subject of significant scientific and clinical interest for years and while experimental evidence reveals that metastasis is not solely a random event, very little is known about the biology of metastasis originating from prostate cancer.

Автор: Jeffrey Myers
Название: Oral Cancer Metastasis
ISBN: 1489984763 ISBN-13(EAN): 9781489984760
Издательство: Springer
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Цена: 174130.00 T
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Описание: Squamous cell carcinoma of the oral cavity (SCCOC) is one of the most prevalent tumors of the head and neck region, but survival rates have not significantly improved. This book summarizes the current status of investigations into SCCOC metastases.

Автор: Tracey A. Martin; Wen G. Jiang
Название: Tight Junctions in Cancer Metastasis
ISBN: 9400798067 ISBN-13(EAN): 9789400798069
Издательство: Springer
Рейтинг:
Цена: 148010.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book summarizes current knowledge of tight junctions and their role in cancer and cancer metastasis. Coverage includes fundamental changes in tight junctions in the process of cancer development and the importance of cellular structure in drug therapy.

Автор: Wen G. Jiang; R.E. Mansel
Название: Cancer Metastasis, Molecular and Cellular Mechanisms and Clinical Intervention
ISBN: 0792363957 ISBN-13(EAN): 9780792363958
Издательство: Springer
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Цена: 231990.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Covers the molecular and cellular aspects of cancer metastasis, and discusses the clinical aspect of micro- and macro-metastases, which result in the death of the majority of patients with cancer. This book attempts to examine the status of the basic scientific and clinical research in the area, and is intended for clinicians and oncologists.

Автор: Volker Schirrmacher; Reinhard Schwartz-Albiez
Название: Cancer Metastasis
ISBN: 3540504710 ISBN-13(EAN): 9783540504719
Издательство: Springer
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Цена: 102480.00 T
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Описание: Proceedings of the 2nd Int. Conference of the Metastasis Research Society of a Satellite Workshop, Heidelberg, September 26-29, 1988