Cell Death Regulation In Health And Disease - Part A,351, Galluzzi, Lorenzo
Автор: Galluzzi, Lorenzo Название: Cell Death Regulation In Health And Disease - Part C,353 ISBN: 0128201355 ISBN-13(EAN): 9780128201350 Издательство: Elsevier Science Рейтинг: Цена: 196510.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Cell Death Regulation in Health and Disease - Part C, Volume 353 in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. The IRCMB series maintains the highest standard by publishing timely topics authored by prominent cell and molecular biologists, with this release covering Developmental and seasonal regulation of neural cell death in birds, Post-translational modifications in cell death regulation, The role of cell death in tissue regeneration and fibrosis, Crosstalk between the apoptosis and autophagy signaling pathways, IP3 receptor signal integration in cell death and survival decisions, and more.
Автор: Galluzzi, Lorenzo Название: Cell Death Regulation In Health And Disease - Part B,352 ISBN: 0128199296 ISBN-13(EAN): 9780128199299 Издательство: Elsevier Science Рейтинг: Цена: 196510.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Cell Death Regulation in Health and Disease - Part B, Volume 352, the latest release in the International Review of Cell and Molecular Biology, reviews and details current advances in cell and molecular biology. Chapters in this updated release include Regulation of cell death signaling in insects, Bcl-2 family proteins, Cell death signaling in prokaryotes, Parthanatos in neurodegenerative diseases, Cell death regulation in yeast, Mutual regulation of autophagy and necroptosis, Therapeutic inhibition of cell death by autophagy induction, and Necroptosis in neurodegenerative diseases.
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Автор: Cameron Wagner Название: Endoplasmic Reticulum Stress: Regulation, Function & Role in Health & Disease ISBN: 1634855647 ISBN-13(EAN): 9781634855648 Издательство: Nova Science Цена: 122490.00 T Наличие на складе: Невозможна поставка. Описание: This book provides current research on the regulation, function and role in health and disease of endoplasmic reticulum (ER) stress. The first chapter focuses on evidence that supports the role of endoplasmic reticulum stress, mitochondria-associated membranes (MAMs) microdomain and oxidative stress during obesity as a molecular pathway to type 2 diabetes mellitus (T2DM) development. Also, it addresses protein missfolding and mitochondria function as potential targets to improve metabolic derangements in obesity and T2DM. Chapter Two summarizes and discusses the current understanding of molecular mechanisms linking ER stress to beta cell fate. Chapter Three depicts the association between eIF2α kinase-linked pathways and diet-linked pathogenic responses (such as ones caused by microbes or nutritional abnormalities). Chapter Four reviews placental endoplasmic reticulum stress in the determination of pregnancy outcome. The last chapter discusses the role of ER stress in meditating the anticancer effects of tocotrienols.
Автор: Pandey, Rajesh Название: Rna-Based Regulation In Human Health And Disease,16 ISBN: 0128171936 ISBN-13(EAN): 9780128171936 Издательство: Elsevier Science Рейтинг: Цена: 176290.00 T Наличие на складе: Нет в наличии. Описание:
RNA-based Regulation in Human Health and Disease offers an in-depth exploration of RNA mediated genome regulation at different hierarchies. Beginning with multitude of canonical and non-canonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational) and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic & neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics.
Dancing protein clouds: Intrinsically disordered proteins in the norm and pathology represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain.
Автор: Seino Название: Pancreatic Beta Cell in Health and Disease ISBN: 4431998373 ISBN-13(EAN): 9784431998372 Издательство: Springer Рейтинг: Цена: 186340.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The beta cells of the pancreatic islets of Langerhans are the only cells in the body that produce and secrete insulin. This book provides a comprehensive review of the beta cell in health and disease.
Автор: Thomas Dittmar; Kurt S. Z?nker Название: Cell Fusion in Health and Disease ISBN: 9400735960 ISBN-13(EAN): 9789400735965 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In these volumes, leading experts present up-to-date overviews about cell fusion in physiological and patho-physiological processes. Volume 1 deals with Cell Fusion in Health, Volume 2 focuses on Cell Fusion in Disease.
Автор: Thomas Dittmar; Kurt S. Z?nker Название: Cell Fusion in Health and Disease ISBN: 9400735715 ISBN-13(EAN): 9789400735712 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This 2-volume set covers the processes of cell fusion in health and disease, including fertilization, placentation, and cell fusion in cellular reprogramming and cancer vaccine development, and on the role of cell fusion in cancer development and progression.
Автор: M. Simionescu; N. Simionescu Название: Endothelial Cell Biology in Health and Disease ISBN: 1461282543 ISBN-13(EAN): 9781461282549 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The number of articles published annually on this subject has increased from a few score at the beginning of the 1970s to more than a thousand in recent years, and an increasing number of journals, books, societies, and symposia focused primarily on the vascular en- dothelium have marked the last decade.
Автор: Hai Chi-Ming Название: Vascular Smooth Muscle: Structure And Function In Health And Disease ISBN: 981314405X ISBN-13(EAN): 9789813144057 Издательство: World Scientific Publishing Цена: 118270.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents key concepts in the structure and function of vascular smooth muscle cells in health and disease. Supplemental reading may be drawn from the extensive references listed at the end of each chapter. Vascular smooth muscle cell is the major cell type in blood vessels. Dysfunction of vascular smooth muscle cells is an important cause of vascular diseases, for example, atherosclerosis, hypertension, and circulatory shock. Vascular smooth muscle cells are phenotypically plastic, capable of switching between two major phenotypes -- contractile/differentiated phenotype and invasive/proliferative phenotype in response to environmental clues. Chapter 1 introduces the major areas of research presented in this monograph. Chapters 2 to 4 address the structure and function of the contractile/differentiated phenotype of vascular smooth muscle cell. Chapters 5 and 6 address the developmental basis of vascular smooth muscle cell phenotype and structure and function of podosomes (invasive organelles) in the invasive/proliferative phenotype of vascular smooth muscle cell. Chapters 7 to 9 address the role of vascular smooth muscle cell dysfunction in vascular diseases -- atherosclerosis, hypertension, and circulatory shock.
Автор: Nikolai Gorbunov Название: Autophagy: Principles, Regulation & Roles in Disease ISBN: 1619422662 ISBN-13(EAN): 9781619422667 Издательство: Nova Science Рейтинг: Цена: 271380.00 T Наличие на складе: Невозможна поставка. Описание: Gives an overview of the biomedical aspects of autophagy research, a large interdisciplinary field emerging on intersection of: cell, developmental, and cancer biology; tissue remodelling and plasticity, ageing and longevity; immunology, microbiology, toxicology, and pathobiology; regenerative and adaptive biomedicine; and, pharmacology.
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