Автор: Degregori James Название: Adaptive Oncogenesis: A New Understanding of How Cancer Evolves Inside Us ISBN: 0674545397 ISBN-13(EAN): 9780674545397 Издательство: Wiley Рейтинг: Цена: 43240.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: James DeGregori proposes a way of thinking about cancer as a disease of evolution-one in which mutated cells outcompete healthy cells in the ecosystem of the body`s tissues. By tying cancer`s progression to natural selection and evolved strategies for reproductive success, his theory goes far in explaining who gets cancer, when it appears, and why.
This invaluable book provides the first description of the diverse and fascinating functions of heme in life processes for a broad audience. It begins with an introduction of the intricate chemical properties of heme and the history of early observations of human diseases associated with heme. It then proceeds to describe the versatile roles of heme in controlling diverse molecular and cellular processes germane to human life and disease processes. In the second edition, a new chapter is devoted to describe findings about heme uptake, transport, and trafficking of heme synthesis intermediates in mammals. Additionally, a chapter about the newly discovered roles of elevated heme biosynthesis and uptake in lung tumorigenesis is included.
Heme Biology is unified and logical in presentation. It is well suited for students and professionals in life sciences who wish to know about the fascinating biology of heme and its usefulness in health and diseases. It may also be used as a reference book for advanced readers and researchers who are interested in heme biology. The explanations in the book are detailed enough to capture the interest of the curious reader, and complete enough to provide the necessary information for researchers to have an in-depth molecular understanding of heme biology and further their studies in this fascinating realm.
Автор: Jatin George Burniston; Yi-Wen Chen Название: Omics Approaches to Understanding Muscle Biology ISBN: 1493998013 ISBN-13(EAN): 9781493998012 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is a collection of principles and current practices in omics research, applied to skeletal muscle physiology and disorders. The various sections are categorized according to the level of biological organization, namely, genomics (DNA), transcriptomics (RNA), proteomics (protein), and metabolomics (metabolite). With skeletal muscle as the unifying theme, and featuring contributions from leading experts in this traditional field of research, it highlights the importance of skeletal muscle tissue in human development, health and successful ageing. It also discusses other fascinating topics like developmental biology, muscular dystrophies, exercise, insulin resistance and atrophy due to disuse, ageing or other muscle diseases, conveying the vast opportunities for generating new hypotheses as well as testing existing hypotheses by combining high-throughput techniques with proper experiment designs, bioinformatics and statistical analyses. Presenting the latest research techniques, this book is a valuable resource for the physiology community, particularly researchers and grad students who want to explore the new opportunities for omics technologies in basic physiology research.
Название: Cancer Cell Signaling ISBN: 1771880678 ISBN-13(EAN): 9781771880671 Издательство: Taylor&Francis Рейтинг: Цена: 137810.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This title includes a number of Open Access chapters.
Cell signaling is a field that studies how cells communicate to control basic activities and respond to their environment. When looking specifically at cancer cells, researchers can gain a better understanding of cancer on a cellular level, an understanding that may have implications for developing new treatments. The current volume provides an overview of the field and how various cell biology techniques are used to better understand cancer on a cellular level. This easily accessible reference volume offers a comprehensive look at the field of cancer cell signaling. Edited by a researcher from Florida Atlantic University, Cancer Cell Signaling: Targeting Signaling Pathways Towards Therapeutic Approaches to Canceris an authoritative and easy-to-use reference.
Название: Apoptosis, Cell Signaling & Human Diseases. Vol2. 2007 ISBN: 1588298825 ISBN-13(EAN): 9781588298829 Издательство: Springer Рейтинг: Цена: 191560.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Provides developments in cell survival and apoptotic pathways and their involvement in various human diseases. This book contains 31 chapters which have been divided into four sections: Malignant Transformation and Metastasis; Kinases and Phosphatases; Molecular Basis of Cell Death; and Molecular Basis of Disease Therapy.
Название: Apoptosis, Cell Signaling & Human Diseases. Vol1. 2007 ISBN: 1588296776 ISBN-13(EAN): 9781588296771 Издательство: Springer Рейтинг: Цена: 191560.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Aims to provide developments in cell survival and apoptotic pathways and their involvement in various human diseases. This book contains 31 chapters which have been divided into four sections: Malignant Transformation and Metastasis; Kinases and Phosphatases; Molecular Basis of Cell Death; and Molecular Basis of Disease Therapy.
Автор: Les Zbigniew, Les Magdalena Название: Machine Understanding: Machine Perception and Machine Perception Mu ISBN: 303024069X ISBN-13(EAN): 9783030240691 Издательство: Springer Рейтинг: Цена: 79190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This unique book discusses machine understanding (MU). This new branch of classic machine perception research focuses on perception that leads to understanding and is based on the categories of sensory objects. In this approach the visual and non-visual knowledge, in the form of visual and non-visual concepts, is used in the complex reasoning process that leads to understanding. The book presents selected new concepts, such as perceptual transformations, within the machine understanding framework, and uses perceptual transformations to solve perceptual problems (visual intelligence tests) during understanding, where understanding is regarded as an ability to solve complex visual problems described in the authors’ previous books. Thanks to the uniqueness of the research topics covered, the book appeals to researchers from a wide range of disciplines, especially computer science, cognitive science and philosophy.
Автор: Tahira Farooqui Название: Oxidative Stress in Vertebrates and Invertebrates: Molecular Aspects of Cell Signaling ISBN: 111800194X ISBN-13(EAN): 9781118001943 Издательство: Wiley Рейтинг: Цена: 161510.00 T Наличие на складе: Поставка под заказ. Описание: This volume presents a unique comparative treatment of the role oxidative stress plays in vertebrates and invertebrates in multiple organ systems with regards to cell death, development, aging, and human diseases, and anti-oxidant therapy.
Автор: Khalid Rehman Hakeem; Reiaz Ul Rehman; Inayatullah Название: Plant signaling: Understanding the molecular crosstalk ISBN: 8132215419 ISBN-13(EAN): 9788132215417 Издательство: Springer Рейтинг: Цена: 174150.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: ГЇВїВЅ Plant signalling has emerged as an integrated field which has become indispensable in recent times to study any biological process. It is now possible to view the different information`s in a systems biology approach which has unravelled the association/ new processes and thus helped us enormously in understanding of the biological processes.
Автор: Khalid Rehman Hakeem; Reiaz Ul Rehman; Inayatullah Название: Plant signaling: Understanding the molecular crosstalk ISBN: 8132234790 ISBN-13(EAN): 9788132234791 Издательство: Springer Рейтинг: Цена: 139310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: ГЇВїВЅ Plant signalling has emerged as an integrated field which has become indispensable in recent times to study any biological process. It is now possible to view the different information`s in a systems biology approach which has unravelled the association/ new processes and thus helped us enormously in understanding of the biological processes.
Автор: Orrenius Название: Mitochondrial Signaling in Health and Disease ISBN: 1439880026 ISBN-13(EAN): 9781439880029 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Mitochondria have traditionally been associated with metabolic functions; however recent research has uncovered a central role for these organelles in cell signaling, cell survival, and cell death. Mitochondrial dysfunction is a factor in a myriad of pathophysiological conditions, including age-related neurodegenerative disorders, cancer, metabolic syndrome, and cardiovascular disease. Mitochondrial Signaling in Health and Disease examines themes essential for the maintenance of the mitochondrial redox (reduction-oxidation) energy axis.
With contributions from an impressive cadre of internationally recognized scientists, the book discusses coordinated mitochondrial functions that regulate cell function by discrete signaling pathways. Topics discussed include:
Electron transport and energy production
Mitochondrial biogenesis and dynamics
Mitochondrial signaling
Apoptosis and autophagy
Pharmacology signaling
Epigenetic signaling: mitochondrial methylation and acetylation reactions
An essential resource for life and health scientists as well as pharmaceutical industry professionals, this volume highlights the importance of mitochondrial signaling and its role in establishing a harmonized communication between several cellular compartments. The information in this volume is critical to those developing mitochondrion-targeted therapies aimed at assuaging mitochondrial dysfunction or the specific factors contributing to its dysfunction.
Автор: Daniele Piomelli Название: Arachidonic Acid in Cell Signaling ISBN: 366205809X ISBN-13(EAN): 9783662058091 Издательство: Springer Рейтинг: Цена: 95770.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is about the arachidonic acid cascade, its biochemistry, its pharmacology, and its roles in signal transduction.
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