Apoptosis, Cell Signaling & Human Diseases. Vol1. 2007, 

Автор: Ralph A. Bradshaw
Название: Regulation of Organelle and Cell Compartment Signaling,
ISBN: 0123822130 ISBN-13(EAN): 9780123822130
Издательство: Elsevier Science
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Цена: 65110.00 T
Наличие на складе: Поставка под заказ.
Описание: Suitable for researchers across molecular biology, biochemistry, cell biology and genetics, this title includes articles that emphasize signaling to and from intracellular compartments including transcriptional responses to cytoplasmic and nuclear signaling events, chromatin remodeling and stress responses, and more.

Название: Apoptosis, Cell Signaling & Human Diseases. Vol2. 2007
ISBN: 1588298825 ISBN-13(EAN): 9781588298829
Издательство: Springer
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Цена: 191560.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Provides developments in cell survival and apoptotic pathways and their involvement in various human diseases. This book contains 31 chapters which have been divided into four sections: Malignant Transformation and Metastasis; Kinases and Phosphatases; Molecular Basis of Cell Death; and Molecular Basis of Disease Therapy.

Автор: Binda, Olivier
Название: Chromatin Signaling and Diseases
ISBN: 0128023899 ISBN-13(EAN): 9780128023891
Издательство: Elsevier Science
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Цена: 116780.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: "

Chromatin Signaling" "and Diseases" covers the molecular mechanisms that regulate gene expression, which govern everything from embryonic development, growth, and human pathologies associated with aging, such as cancer. This book helps researchers learn about or keep up with the quickly expanding field of chromatin signaling.

After reading this book, clinicians will be more capable of explaining the mechanisms of gene expression regulation to their patients to reassure them about new drug developments that target chromatin signaling mechanisms. For example, several epigenetic drugs that act on chromatin signaling factors are in clinical trials or even approved for usage in cancer treatments, Alzheimer's, and Huntington's diseases. Other epigenetic drugs are in development to regulate various class of chromatin signaling factors. To keep up with this changing landscape, clinicians and doctors will need to stay familiar with genetic advances that translate to clinical practice, such as chromatin signaling.

Although sequencing of the human genome was completed over a decade ago and its structure investigated for nearly half a century, molecular mechanisms that regulate gene expression remain largely misunderstood. An emerging concept called chromatin signaling proposes that small protein domains recognize chemical modifications on the genome scaffolding histone proteins, facilitating the nucleation of enzymatic complexes at specific loci that then open up or shut down the access to genetic information, thereby regulating gene expression. The addition and removal of chemical modifications on histones, as well as the proteins that specifically recognize these, is reviewed in "Chromatin Signaling and Diseases." Finally, the impact of gene expression defects associated with malfunctioning chromatin signaling is also explored.
Explains molecular mechanisms that regulate gene expression, which governs everything from embryonic development, growth, and human pathologies associated with agingEducates clinicians and researchers about chromatin signaling, a molecular mechanism that is changing our understanding of human pathologyExplores the addition and removal of chemical modifications on histones, the proteins that specifically recognize these, and the impact of gene expression defects associated with malfunctioning chromatin signalingHelps researchers learn about the quickly expanding field of chromatin signaling

Название: Apoptosis: The Molecular Biology of Programmed Cell Death
ISBN: 0199638497 ISBN-13(EAN): 9780199638499
Издательство: Oxford Academ
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Цена: 95040.00 T
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Описание: This work is intended for postgraduate students in cell biology, postdoctoral researchers new to the field, advanced undergraduates, postgraduate medical students, and clinicians undertaking research training in the area.

Автор: Dennis
Название: Handbook of Cell Signaling on CD
ISBN: 0121245519 ISBN-13(EAN): 9780121245511
Издательство: Elsevier Science
Цена: 173860.00 T
Наличие на складе: Невозможна поставка.
Описание: In this latest immunology reference, thirty chapters discuss a wide range of basic and clinical/applied immunology topics. Each chapter has been extensively and individually reviewed by a group of highly esteemed experts to ensure systematic timely coverage of each subject. High quality photographs illustrate the connection between understanding basic immunology and the impact of immunological disorders in the clinic. It will prove an invaluable resource for teachers, lecturers and a vital reference for research scientists throughout the life sciences.