Antibodies in Diagnosis and Therapy, Matzku,

Автор: Suresh C. Srivastava
Название: Radiolabeled Monoclonal Antibodies for Imaging and Therapy
ISBN: 1468455400 ISBN-13(EAN): 9781468455403
Издательство: Springer
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Цена: 113190.00 T
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Описание: The advent of hybridoma technology leading to the successful produc- tion of monoclonal antibodies against a variety of tumor-associated antigens has, during the last decade, provided a very powerful tool for research and clinical investigations.

Автор: Shepherd
Название: Monoclonal Antibodies
ISBN: 0199637229 ISBN-13(EAN): 9780199637225
Издательство: Oxford Academ
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Цена: 89760.00 T
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Описание: This text covers the preparation, testing, derivation and application of monoclonal antibodies. Modern immunological techniques incorporating tried and tested methodologies are described, as well as the standard somatic hybridization and recombinant techniques, including the use of phage libraries.

Автор: Albitar Maher
Название: Monoclonal antibodies / methods and protocols
ISBN: 1588295672 ISBN-13(EAN): 9781588295675
Издательство: Springer
Рейтинг:
Цена: 144410.00 T
Наличие на складе: Нет в наличии.
Описание: Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins. Specific chapters describe how antibodies are used for the diagnosis and classification of hematologic diseases. Subsequent chapters examine the advantages and most recent advances of using bead-based immunoassays, including the ability of bead-based technology to multiplex and analyze several analytes simultaneously, and the use of beads in detecting fusion proteins resulting from chromosomal translocations. Concluding chapters provide additional examples of methodologies that employ monoclonal antibodies.Monoclonal Antibodies: Methods and Protocols provides descriptions of methods that cover a wide spectrum of applications in the field of monoclonal antibodies. This field will continue to expand and provide new and innovative techniques, not only in the laboratory, but also as a basis that complements targeted therapy.

Автор: Juan J. Lafaille; Maria A. Curotto de Lafaille
Название: IgE Antibodies: Generation and Function
ISBN: 331935888X ISBN-13(EAN): 9783319358888
Издательство: Springer
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Цена: 113180.00 T
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Описание: This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites.

Автор: Roland E. Kontermann
Название: Bispecific Antibodies
ISBN: 3642432077 ISBN-13(EAN): 9783642432071
Издательство: Springer
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Цена: 204970.00 T
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Описание: The concept of using bispecific antibodies for cancer therapy by retargeting immune effector cells was developed several years ago. Initial clinical studies were rather disappointing mainly due to low efficacy, severe side effects and the immunogenicity of the bispecific antibodies. The progress in antibody engineering finally led to the generation of new classes of bispecific antibodies lacking these obstacles. In addition, new applications were established, such as pre-targeting strategies in radioimmunotherapy and dual targeting approaches in order to improve binding, selectivity and efficacy. In this book, the different ways of generating bispecific antibodies are described, with emphasis on recombinant formats. The various applications of bispecific antibodies, e.g. in cellular cancer immunotherapy, radioimmunotherapy and pretargeting strategies are covered, and emerging applications such as dual targeting strategies, which involve the simultaneous inhibition of two targets, are addressed.

Название: The Antibodies
ISBN: 0367454874 ISBN-13(EAN): 9780367454876
Издательство: Taylor&Francis
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Цена: 63280.00 T
Наличие на складе: Невозможна поставка.
Описание: From diagnostic tools to therapy against cancer, infections and autoimmune diseases, antibodies serve many purposes, yet our knowledge of them is still incomplete. The Antibodies: Volume 7 continues with a comprehensive review of topics of contemporary interest including major breakthroughs such as the advent of monoclonal antibodies and the develo

Автор: Michael Steinitz
Название: Human Monoclonal Antibodies
ISBN: 1493960199 ISBN-13(EAN): 9781493960194
Издательство: Springer
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Цена: 111790.00 T
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Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.

Автор: Benjamin Bonavida
Название: Resistance to Immunotherapeutic Antibodies in Cancer
ISBN: 1461476534 ISBN-13(EAN): 9781461476535
Издательство: Springer
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Цена: 156720.00 T
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Описание: This book examines antibody-mediated anti-cancer therapy, covering the use of mAbs against various cancers, developments in the molecular, biochemical and genetic mechanisms of resistance by various mAbs and novel mAbs to overcome drug and radition resistance.

Автор: R. Gieseler; Johann H. Peters; G. K?hler; P. Debba
Название: Monoclonal Antibodies
ISBN: 3642745342 ISBN-13(EAN): 9783642745348
Издательство: Springer
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Цена: 121890.00 T
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Описание: With contributions by numerous authors

Автор: Antonino Cattaneo; Silvia Biocca
Название: Intracellular Antibodies
ISBN: 3662079941 ISBN-13(EAN): 9783662079942
Издательство: Springer
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Цена: 46570.00 T
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Описание: Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells.

Автор: John Landon; Tim Chard
Название: Therapeutic Antibodies
ISBN: 1447119398 ISBN-13(EAN): 9781447119395
Издательство: Springer
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Цена: 95770.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Several aspects of clinical medicine are poised on the edge of a new era with the introduction of therapeutic antibodies. This volume is aimed at all clinicians involved with this form of treatment, especially accident and emergency physicians, clinical immunologists, and pharmacologists.