Автор: Zola, Heddy Название: Monoclonal Antibodies ISBN: 0367451425 ISBN-13(EAN): 9780367451424 Издательство: Taylor&Francis Рейтинг: Цена: 63280.00 T Наличие на складе: Невозможна поставка. Описание: This book is intended to enable biologists and medical scientists to answer questions for themselves, in the context of their own particular needs. It provides detailed methodology to enable readers to make their own antibodies and to use monoclonal antibodies to their best advantage.
Автор: David M. Goldenberg Название: Cancer Imaging with Radiolabeled Antibodies ISBN: 1461288053 ISBN-13(EAN): 9781461288053 Издательство: Springer Рейтинг: Цена: 343800.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: It is an attempt to establish a critical mass of oncology literature covering virtually all oncology topics, revised frequently to keep the coverage up to date, and easily available on a single library shelf or by a single personal subscription.
Автор: Juan J. Lafaille; Maria A. Curotto de Lafaille Название: IgE Antibodies: Generation and Function ISBN: 331935888X ISBN-13(EAN): 9783319358888 Издательство: Springer Рейтинг: Цена: 113180.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites.
Автор: Hans U. Lutz Название: Naturally Occurring Antibodies (NAbs) ISBN: 1493953311 ISBN-13(EAN): 9781493953318 Издательство: Springer Рейтинг: Цена: 174130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Here, pioneering researchers report on the tissue homeostatic, tissue regenerating and regulatory properties of NAbs and NAbs in pooled human IgG. The volume also has a chapter on the history of how pooled plasma was pretreated for safe intravenous use.
Автор: Steinitz Michael Название: Human Monoclonal Antibodies: Methods and Protocols ISBN: 149398957X ISBN-13(EAN): 9781493989577 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This second edition volume expands on the previous edition with descriptions of recent developments in the field. The chapters in this book cover topics such as monoclonal antibodies for the treatment of melanoma; production and purification of human monoclonal antibodies; humanization and optimization of monoclonal antibodies; rapid chimerization of monoclonal antibodies; epitope mapping via phage display from single gene libraries; recombinant antibodies made by combining phage and yeast display selections; production of stabilized antibody fragments in the E. coli bacterial cytoplasm and transfected mammalian cells; and analysis of CAR T cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Unique and thorough, Human Monoclonal Antibodies: Methods and Protocols, Second Edition is a valuable tool for novice and expert researchers interested in learning more about this evolving field.
Автор: Bazin Название: Rat Hybridomas and Rat Monoclonal Antibodies (1990) ISBN: 1138506109 ISBN-13(EAN): 9781138506107 Издательство: Taylor&Francis Рейтинг: Цена: 275610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The purpose of this book is to provide information which supports the fact that rat hybridomas are no more difficult to develop than mouse hybridomas.
Автор: Antonino Cattaneo; Silvia Biocca Название: Intracellular Antibodies ISBN: 3662079941 ISBN-13(EAN): 9783662079942 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells.
Автор: Roland E. Kontermann Название: Bispecific Antibodies ISBN: 3642432077 ISBN-13(EAN): 9783642432071 Издательство: Springer Рейтинг: Цена: 204970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The concept of using bispecific antibodies for cancer therapy by retargeting immune effector cells was developed several years ago. Initial clinical studies were rather disappointing mainly due to low efficacy, severe side effects and the immunogenicity of the bispecific antibodies. The progress in antibody engineering finally led to the generation of new classes of bispecific antibodies lacking these obstacles. In addition, new applications were established, such as pre-targeting strategies in radioimmunotherapy and dual targeting approaches in order to improve binding, selectivity and efficacy. In this book, the different ways of generating bispecific antibodies are described, with emphasis on recombinant formats. The various applications of bispecific antibodies, e.g. in cellular cancer immunotherapy, radioimmunotherapy and pretargeting strategies are covered, and emerging applications such as dual targeting strategies, which involve the simultaneous inhibition of two targets, are addressed.
Автор: Jeffrey V. Ravetch; Falk Nimmerjahn Название: Fc Mediated Activity of Antibodies ISBN: 3030310523 ISBN-13(EAN): 9783030310523 Издательство: Springer Рейтинг: Цена: 79190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume explores several aspects of how antibodies mediate their activity in vivo, ranging from cancer immunotherapy to autoimmunity, infection, and vaccination. Divided into seven chapters, it provides in-depth insights into how antibodies and especially the antibody fragment crystallizable (Fc) domain modulate immune responses and antibody activity. The book begins by discussing evolutionary aspects of how the family of Fc receptors that are the key molecules for antibody activity evolved. In turn, it addresses the molecular and cellular pathways underlying IgG activity in cancer immunotherapy, and focuses on how IgG glycosylation regulates IgG and IgE activity in autoimmunity, allergy and infection. In closing, it presents strategies for developing novel antibody-based vaccination approaches. The book is intended for a very broad readership, including graduate students, postdocs and principal investigators with a basic grasp of immunology.
Автор: Bazin Название: Revival: Rat Hybridomas and Rat Monoclonal Antibodies (1990) ISBN: 1138561649 ISBN-13(EAN): 9781138561649 Издательство: Taylor&Francis Рейтинг: Цена: 76550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The purpose of this book is to provide information which supports the fact that rat hybridomas are no more difficult to develop than mouse hybridomas. This is the first book devoted to the development of rat hybridomas. It includes theories, step-by-step techniques, ingredients and apparatus.
Автор: Ron Hubbard; Vincent Marks Название: Clinical Applications of Monoclonal Antibodies ISBN: 1461288614 ISBN-13(EAN): 9781461288619 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Immunology has come a long way in the hundred or so years since the general concepts were first enuciated by Metchnikoff, Ehrlich, Von Bebring and others, One of the landmarks in this progress was the invention and development of monoclonal antibody secreting hybridomas by Milstein and bis co-workers in Cambridge.
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