Контакты/Проезд  Доставка и Оплата Помощь/Возврат
История
  +7 707 857-29-98
  +7(7172) 65-23-70
  10:00-18:00 пн-пт
  shop@logobook.kz
   
    Поиск книг                        
Найти
  Зарубежные издательства Российские издательства  
Авторы | Каталог книг | Издательства | Новинки | Учебная литература | Акции | Бестселлеры | |
 

Bispecific Antibodies, Roland E. Kontermann


Варианты приобретения
Цена: 204970.00T
Кол-во:
Наличие: Поставка под заказ.  Есть в наличии на складе поставщика.
Склад Америка: 195 шт.  
При оформлении заказа до: 2025-07-28
Ориентировочная дата поставки: Август-начало Сентября
При условии наличия книги у поставщика.

Добавить в корзину
в Мои желания

Автор: Roland E. Kontermann
Название:  Bispecific Antibodies
ISBN: 9783642432071
Издательство: Springer
Классификация:

ISBN-10: 3642432077
Обложка/Формат: Paperback
Страницы: 373
Вес: 0.55 кг.
Дата издания: 13.12.2014
Язык: English
Издание: 2011 ed.
Иллюстрации: Xvii, 373 p.
Размер: 234 x 156 x 21
Читательская аудитория: General (us: trade)
Основная тема: Biomedicine
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание: The concept of using bispecific antibodies for cancer therapy by retargeting immune effector cells was developed several years ago. Initial clinical studies were rather disappointing mainly due to low efficacy, severe side effects and the immunogenicity of the bispecific antibodies. The progress in antibody engineering finally led to the generation of new classes of bispecific antibodies lacking these obstacles. In addition, new applications were established, such as pre-targeting strategies in radioimmunotherapy and dual targeting approaches in order to improve binding, selectivity and efficacy. In this book, the different ways of generating bispecific antibodies are described, with emphasis on recombinant formats. The various applications of bispecific antibodies, e.g. in cellular cancer immunotherapy, radioimmunotherapy and pretargeting strategies are covered, and emerging applications such as dual targeting strategies, which involve the simultaneous inhibition of two targets, are addressed.
Дополнительное описание: Janice M. Reichert: Foreword.- Roland Kontermann: Bispecific antibodies: developments and current perspectives.- Gerd Moldenhauer: Bispecific antibodies from hybrid hybridoma.- Diego Ellerman & Justin Scheer: Generation of bispecific antibodies by chemica


Therapeutic Antibodies

Автор: Antony S. Dimitrov (Ed.)
Название: Therapeutic Antibodies
ISBN: 1934115924 ISBN-13(EAN): 9781934115923
Издательство: Springer
Рейтинг:
Цена: 204970.00 T
Наличие на складе: Поставка под заказ.
Описание: Presents a set of protocols for the discovery and development of therapeutic antibodies, featuring sections focusing on recombinant antigens, antibody libraries, antibody discovery, antibody engineering and antibody preclinical development. This work is suitable for those investigating and participating in this therapeutic market segment.

Making and Using Antibodies

Автор: Howard
Название: Making and Using Antibodies
ISBN: 1439869081 ISBN-13(EAN): 9781439869086
Издательство: Taylor&Francis
Рейтинг:
Цена: 163330.00 T
Наличие на складе: Невозможна поставка.
Описание:

Antibodies protect us from a wide range of infectious diseases and cancers and have become an indispensable tool in science--both for conventional immune response research as well as other areas related to protein identification analysis. This second edition of Making and Using Antibodies: A Practical Handbook provides clear guidance on all aspects of how to make and use antibodies for research along with their commercial and industrial applications.

Keeping pace with new developments in this area, all chapters in this new edition have been revised, updated, or expanded. Along with discussions of current applications, new material in the book includes chapters on western blotting, aptamers, antibodies as therapeutics, quantitative production, and humanization of antibodies. The authors present clear descriptions of basic methods for making and using antibodies and supply detailed descriptions of basic laboratory techniques. Each chapter begins with introductory material, allowing for a better understanding of each concept, and practical examples are included to help readers grasp the real-world scenarios in which antibodies play a part.

From the eradication of smallpox to combating cancer, antibodies present an attractive solution to a range of biomedical problems. They are relatively easy to make and use, have great flexibility in applications, and are cost effective for most labs. This volume will assist biomedical researchers and students and pave the way for future discovery of new methods for making and using antibodies for a host of applications.


Human Monoclonal Antibodies: Methods and Protocols

Автор: Michael Steinitz (Editor)
Название: Human Monoclonal Antibodies: Methods and Protocols
ISBN: 1627035850 ISBN-13(EAN): 9781627035859
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.

Monoclonal Antibodies

Автор: Shepherd
Название: Monoclonal Antibodies
ISBN: 0199637229 ISBN-13(EAN): 9780199637225
Издательство: Oxford Academ
Рейтинг:
Цена: 89760.00 T
Наличие на складе: Поставка под заказ.
Описание: This text covers the preparation, testing, derivation and application of monoclonal antibodies. Modern immunological techniques incorporating tried and tested methodologies are described, as well as the standard somatic hybridization and recombinant techniques, including the use of phage libraries.

Manual of Diagnostic Antibodies for Immunohistology

Автор: Anthony S-Y. Leong
Название: Manual of Diagnostic Antibodies for Immunohistology
ISBN: 1841101001 ISBN-13(EAN): 9781841101002
Издательство: Cambridge Academ
Рейтинг:
Цена: 176350.00 T
Наличие на складе: Поставка под заказ.
Описание: The rapid acceptance of immunohistochemistry as an important and even indispensable adjunct to morphological examination and diagnosis requires the modern anatomical pathology laboratory to be conversant with, and proficient in, immunostaining procedures, as well as methods of tissue processing and antigen retrieval and the underlying characteristics of the increasing number of antibodies and antisera available. This fully revised, expanded and updated edition provides a comprehensive list of antisera and monoclonal antibodies that have useful diagnostic applications in tissue sections and cell preparations. Various clones, which are commercially available to detect the same antigen, are listed and the sensitivities and specificities of the antibodies are discussed. Importantly, the authors, all pathologists with a wealth of experience in immunostaining procedures, provide fully referenced details and expert advice on each reagent, with the reader will find invaluable. Finally, the appendices provide easily accessible and clear summaries of selected antibody panels for specific diagnostic situations, details of heat-induced antigen/epitope retrieval (including the use of microwaves) and a useful reference to the websites of the main antibody suppliers.

Monoclonal Antibodies in Transplantation

Автор: Lucienne Chatenoud
Название: Monoclonal Antibodies in Transplantation
ISBN: 3662221977 ISBN-13(EAN): 9783662221976
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Experimental and clinical evidence presented in this book illustrates that antibodies expressing different specificities can be very effective in preventing or reversing established transplant rejection.

Clinical Applications of Monoclonal Antibodies

Автор: Ron Hubbard; Vincent Marks
Название: Clinical Applications of Monoclonal Antibodies
ISBN: 1461288614 ISBN-13(EAN): 9781461288619
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Immunology has come a long way in the hundred or so years since the general concepts were first enuciated by Metchnikoff, Ehrlich, Von Bebring and others, One of the landmarks in this progress was the invention and development of monoclonal antibody secreting hybridomas by Milstein and bis co-workers in Cambridge.

Intracellular Antibodies

Автор: Antonino Cattaneo; Silvia Biocca
Название: Intracellular Antibodies
ISBN: 3662079941 ISBN-13(EAN): 9783662079942
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Recent advances in the field of recombinant antibodies have permitted the manipulation of genes encoding specific antibodies, thus allowing their ectopic expression in a wide variety of non-lymphoid cells.

Clinical Use of Antibodies

Автор: Richard P. Baum; P.H. Cox; Gustav H?r; Gian Luigi
Название: Clinical Use of Antibodies
ISBN: 9401055556 ISBN-13(EAN): 9789401055550
Издательство: Springer
Рейтинг:
Цена: 93160.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: It was at Frankfurt/Mainin 1899 that Paul Ehrlich first expounded his famous "site-chain theory" -which described the basic immunological principal of antibody-antigen interactio- on the occasion of the opening of the Institute for Experimental Therapeutics (which was later named after him).

Antibodies

Автор: G. Subramanian
Название: Antibodies
ISBN: 1461347017 ISBN-13(EAN): 9781461347019
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

If the antibody industry is to achieve its full potential in the next decade, the individual technical potentials must be exploited, the limitations must be addressed, and lessons learned must be applied both to current purification methods and to the new technologies that continue to emerge. This book presents an overview of the current advances applied in the manufacture of monoclonal antibody including:
-concepts in development of manufacturing strategies,
-importance of antibody fragments,
-application of chromatography method development,
-quality control,
-effect of expression on antibody properties,
-virus removal and safety,
-pharmacokinetics,
-regulatory aspects.

Antibodies Volume 1: Production and Purification together with Volume 2: Novel Technologies and Therapeutic Use will be of great value to all of those who are actively working in the field of antibodies.
Volume 2: Novel Technologies and Therapeutic Use brings to the forefront current advances in novel technologies for the manufacturing of monoclonal antibodies and also their extensive clinical importance. Following on from Antibodies Volume 1: Production and Purification, this volume concentrates on:
-new technologies in the manufacture of monoclonal antibodies,
-the application of antibodies in cancer therapy and functional genomic therapy,
-the importance of antibodies and prospects of antibody engineering for the future.


Melanoma Antigens and Antibodies

Автор: Ralph A. Reisfeld; Soldano Ferrone
Название: Melanoma Antigens and Antibodies
ISBN: 1468440810 ISBN-13(EAN): 9781468440812
Издательство: Springer
Рейтинг:
Цена: 46570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Introduction . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

The Pharmacology of Monoclonal Antibodies

Автор: Martin Rosenberg; R. Balint; Gordon P. Moore; C.F.
Название: The Pharmacology of Monoclonal Antibodies
ISBN: 3642784348 ISBN-13(EAN): 9783642784347
Издательство: Springer
Рейтинг:
Цена: 121110.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This rapidly-evolving field has witnessed the PCR combinatorial cloning of vast immunological diversity, in vitro mutagenesis of MAbs, MAbs created by transgenic animals, novel expression systems in plants, animals and lower systems, as well as a rich variety of genetically modified MAbs as potential therapeutic agents.


Казахстан, 010000 г. Астана, проспект Туран 43/5, НП2 (офис 2)
ТОО "Логобук" Тел:+7 707 857-29-98 ,+7(7172) 65-23-70 www.logobook.kz
Kaspi QR
   В Контакте     В Контакте Мед  Мобильная версия