Автор: Michael Steinitz Название: Human Monoclonal Antibodies ISBN: 1493960199 ISBN-13(EAN): 9781493960194 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.
Автор: Steinitz Michael Название: Human Monoclonal Antibodies: Methods and Protocols ISBN: 149398957X ISBN-13(EAN): 9781493989577 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This second edition volume expands on the previous edition with descriptions of recent developments in the field. The chapters in this book cover topics such as monoclonal antibodies for the treatment of melanoma; production and purification of human monoclonal antibodies; humanization and optimization of monoclonal antibodies; rapid chimerization of monoclonal antibodies; epitope mapping via phage display from single gene libraries; recombinant antibodies made by combining phage and yeast display selections; production of stabilized antibody fragments in the E. coli bacterial cytoplasm and transfected mammalian cells; and analysis of CAR T cells. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Unique and thorough, Human Monoclonal Antibodies: Methods and Protocols, Second Edition is a valuable tool for novice and expert researchers interested in learning more about this evolving field.
Автор: Vincent Ossipow; Nicolas Fischer Название: Monoclonal Antibodies ISBN: 1493963228 ISBN-13(EAN): 9781493963225 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Monoclonal Antibodies: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed modern approaches to isolate and characterize monoclonal antibodies against carefully selected epitopes. This edition includes new chapters covering the key steps to generate high quality monoclonals via different methods, from antigen generation to epitope mapping and quality control of the purified IgG. Chapters are divided into four parts corresponding to four distinct objectives. Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody expression and purification, Part III presents methods for monoclonal antibody characterization and modification, and Part IV describes selected applications of monoclonal antibodies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Monoclonal Antibodies: Methods and Protocols, Second Edition provides crucial initial steps of monoclonal antibody generation and characterization with state-of-the art protocols.
Автор: Marie-Luise Sautter-Bihl; Heiner Bihl; Michael Wan Название: Systemic Radiotherapy with Monoclonal Antibodies ISBN: 364279954X ISBN-13(EAN): 9783642799549 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Almost a century ago Paul Ehrlich introduced the "magic bullet" concept of targeting therapeutic agents to specific tissues in order to reduce systemic toxicity.
Автор: James W. Larrick; C. Borrebaeck Название: Therapeutic Monoclonal Antibodies ISBN: 1349118966 ISBN-13(EAN): 9781349118960 Издательство: Springer Рейтинг: Цена: 104480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A review of therapeutic antibodies which have commercial potential. It discusses PCR cloning of Igs, immortalization by gene transfer, scale up production, infectious diseases, viruses, bacteria, parisites, inflammation/immunology, blood grouping, cells, cytokines, tumours and MDR.
Автор: Stewart Sell; Ralph Reisfeld Название: Monoclonal Antibodies in Cancer ISBN: 0896030687 ISBN-13(EAN): 9780896030688 Издательство: Springer Рейтинг: Цена: 204040.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Monoclonal antibody technology from its earliest moments has offered revolutionary expectations for the diagnosis and treatment of cancer.
Автор: R. Gieseler; Johann H. Peters; G. K?hler; P. Debba Название: Monoclonal Antibodies ISBN: 3642745342 ISBN-13(EAN): 9783642745348 Издательство: Springer Рейтинг: Цена: 121890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions by numerous authors
Автор: Vincent Ossipow; Nicolas Fischer Название: Monoclonal Antibodies ISBN: 1627039910 ISBN-13(EAN): 9781627039918 Издательство: Springer Рейтинг: Цена: 214280.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody expression and purification, Part III presents methods for monoclonal antibody characterization and modification, and Part IV describes selected applications of monoclonal antibodies.
Автор: Bazin Название: Rat Hybridomas and Rat Monoclonal Antibodies (1990) ISBN: 1138506109 ISBN-13(EAN): 9781138506107 Издательство: Taylor&Francis Рейтинг: Цена: 275610.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The purpose of this book is to provide information which supports the fact that rat hybridomas are no more difficult to develop than mouse hybridomas.
Автор: Martin Rosenberg; R. Balint; Gordon P. Moore; C.F. Название: The Pharmacology of Monoclonal Antibodies ISBN: 3642784348 ISBN-13(EAN): 9783642784347 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This rapidly-evolving field has witnessed the PCR combinatorial cloning of vast immunological diversity, in vitro mutagenesis of MAbs, MAbs created by transgenic animals, novel expression systems in plants, animals and lower systems, as well as a rich variety of genetically modified MAbs as potential therapeutic agents.
Автор: R. Ceriani Название: Monoclonal Antibodies and Breast Cancer ISBN: 0898387396 ISBN-13(EAN): 9780898387391 Издательство: Springer Рейтинг: Цена: 222670.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the International Workshop on Monoclonal Antibodies and Breast Cancer, held in San Francisco, California, November 8-9, 1984
Автор: Maher Albitar Название: Monoclonal Antibodies ISBN: 1617376469 ISBN-13(EAN): 9781617376467 Издательство: Springer Рейтинг: Цена: 144410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting. The chapters offer in-depth description for generating mouse and recombinant humanized antibodies, and a comprehensive review of how antibodies are being used in bead-based methods for measuring proteins.
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