Proteomics of Peroxisomes, Luis A. del R?o; Michael Schrader
Автор: Michael Schrader Название: Peroxisomes ISBN: 1493969358 ISBN-13(EAN): 9781493969357 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
1. Isolation of Peroxisomes from Rat Liver and Cultured Hepatoma Cells by Density Gradient Centrifugation
Andreas Manner and Markus Islinger
2. Isolation of Peroxisomes from Mouse Brain Using a Continuous Nycodenz Gradient: A Comparison to the Isolation of Liver and Kidney Peroxisomes
Miriam J. Schцnenberger and Werner J. Kovacs
3. Determining the Topology of Peroxisomal Proteins Using Protease Protection Assays
Tвnia Francisco, Ana F. Dias, Ana G. Pedrosa, Clбudia P. Grou, Tony A. Rodrigues, and Jorge E. Azevedo
4. Isolation of Native Soluble and Membrane-Bound Protein Complexes from Yeast Saccharomyces Cerevisiae
Tobias Hansen, Anna Chan, Thomas Schrцter, Daniel Schwerter, Wolfgang Girzalsky, and Ralf Erdmann
5. Method for Measurement of Peroxisomal Very Long-Chain Fatty Acid Beta-Oxidation and de novo C26:0 Synthesis Activity in Living Cells Using Stable-Isotope Labelled Docosanoic Acid
Malu-Clair van de Beek, Inge M.E. Dijkstra, and Stephan Kemp
6. Analysis of Plasmalogen Synthesis in Cultured Cells
Masanori Honsho and Yukio Fujiki
7. Transfection of Primary Human Skin Fibroblasts for Peroxisomal Studies
Janet Koster and Hans R. Waterham
8. siRNA-Mediated Silencing of Peroxisomal Genes in Mammalian Cells
Tina A. Schrader and Michael Schrader
9. Dual Reporter Systems for the Analysis of Translational Readthrough in Mammals
Julia Hofhuis, Severin Dieterle, Rosemol George, Fabian Schueren, and Sven Thoms
10. Cytochemical Detection of Peroxisomes in Light and Electron Microscopy with 3,3'-diaminobenzidine
H. Dariush Fahimi
11. Cryo-Immuno Electron Microscopy of Peroxisomal Marker Proteins
Karina Mildner and Dagmar Zeuschner
12. Detection and Immunolabelling of Peroxisomal Proteins
Tina Schrader, Markus Islinger, and Michael Schrader
13. Labelling of Peroxisomes for Live Cell Imaging in the Filamentous Fungus Ustilago Maydis
Sofia C. Guimaraes, Sreedhar Kilaru, Michael Schrader, and Martin Schuster
14. Quantitative Monitoring of Subcellular Redox Dynamics in Living Mammalian Cells Using RoGFP2-based Probes
Celien Lismont, Paul A. Walton, and Marc Fransen
15. KillerRed as a Tool to Study the Cellular Responses to Peroxisome-Derived Oxidative Stress
Marc Fransen and Chantal Brees
16. Determination of Peroxisomal pH in Living Mammalian Cells Using pHRed
Luis F. Godinho, and Michael Schrader
17. In Cellulo Approaches to Study Peroxisomal Protein Import - Yeast Immunofluorescence Microscopy
Tobias Hansen, Wolfgang Girzalsky, and Ralf Erdmann
18. Blue Native Page: Applications to Study Peroxisome Biogenesis
Kanji Okumoto, Shigehiko Tamura, and Yukio Fujiki
19. In Vitro PMP Import Analysis Using Cell-Free Synthesized PMP and Isolated Peroxisomes
Yuqiong Liu, Masanori Honsho, and Yukio Fujiki
20. Peroxisomal Membrane and Matrix Protein Import Using a Semi-Intact Mammalian Cell System
Kanji Okumoto, Masanori Honsho, Yuqiong Liu, and Yukio Fujiki
21. The Use of Glycosylation Tags as Reporters for Protein Entry into the Endoplasmic Reticulum in Yeast and Mammalian Cells
Judith Buentzel, and Sven Thoms
22. Detection of Ubiquitinated Peroxisomal Proteins in Yeast
Natasha Danda and Chris Williams
23. Assessing Pexophagy in Mammalian Cells
Shun-ichi Yamashita and Yukio Fujiki
24. Experimental Systems to Study Yeast Pexophagy
Shun-ichi Yamashita, Masahide O
Автор: Tsuneo Imanaka; Nobuyuki Shimozawa Название: Peroxisomes: Biogenesis, Function, and Role in Human Disease ISBN: 9811511683 ISBN-13(EAN): 9789811511684 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book provides readers with a comprehensive overview of peroxisomes and their role in human diseases. It starts by describing the history of peroxisome research and then examines in detail the current understanding of the biogenesis and function of peroxisomes. It then focuses on peroxisomal disorders and the involvement of peroxisomes in cancer and age-related diseases, discussing in detail the use of model organisms to elucidate the pathogenesis of peroxisomal disorders and the physiological importance of peroxisomal proteins. Further, the book examines diagnostic and therapeutic strategies in peroxisomal disorders as well as significant recent advances. Lastly, it addresses various topics in peroxisome research, including the isolation of peroxisomes from mammalian tissues and cells, the structural biology of peroxisomal proteins, the lipidomics of peroxisomal disorders, the value of exome sequencing, and neuropsychological testing in X-linked adrenoleukodystrophy. Given its scope, the book is a valuable resource for postgraduate students and researchers in the life sciences and clinicians in the fields of internal medicine, pediatrics, and neurology.
Автор: H. Dariush Fahimi; Helmut Sies Название: Peroxisomes in Biology and Medicine ISBN: 3642713270 ISBN-13(EAN): 9783642713279 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Peroxisomes (microbodies) have a long evolutionary lifespan, but in cell biology they are still young. It is gratifying to see that most recent advances in our knowledge of peroxisomes come from quite different disciplines, ranging from molecular biology and cell biology to clinical research. The identification in terms of cDNA sequences of enzymes, the localization in terms of immuno-electron microscopy, and the cell biological aspects of the organelle biogenesis have seen substantial progress very recently. Likewise, the phenomenon of peroxisome proliferation induced by a number of drugs, e. g. hypolipidemics and plasticizers, constitute an active area of research, where much is still to be learnt. The medical problem of inborn errors of metabolism seems to have gained a new realm for discovery. Here, the advances in knowledge within the last year have been particularly striking. Therefore, the "International Symposium on Peroxisomes in Biology and Medicine," held in Heidelberg from July 14-17,1986, was even more excit- ing than could have initially been anticipated. The present volume consists of papers from that conference. For sake of rapid publication, the camera- ready format, inspite of all its drawbacks (e. g. no proof reading by authors), was chosen. It is our pleasure to acknowledge support and help. The Symposium was supported by Deutsche Forschungsgemeinschaft, Bonn, by the Ministerium ftir Wissenschaft und Kunst Baden-Wtirttemberg, Stuttgart, as well as by a number of generous contributors from industry.
Автор: R.J. Pollitt; A.H. van Gennip; C.J. de Groot; G.M. Название: Inborn Errors of Cellular Organelles: Peroxisomes and Mitochondria ISBN: 9401079277 ISBN-13(EAN): 9789401079273 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Proceedings of the 24th Annual Symposium of the SSIEM held in Amersfoort, the Netherlands, September 1986.
Автор: J.-C. Fruchart; Antonio M. Gotto Jr.; Rodolfo Paol Название: Peroxisome Proliferator Activated Receptors: From Basic Science to Clinical Applications ISBN: 140207199X ISBN-13(EAN): 9781402071997 Издательство: Springer Рейтинг: Цена: 186340.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Peroxisome Proliferator Activated Receptors (PPARs) attract great attention in light of the wide spectrum of genes of biological and medical relevance identified as under their control. This volume provides a view of the clinical and scientific developments within this area of study.
Автор: Luis A. del R?o; Michael Schrader Название: Proteomics of Peroxisomes ISBN: 9811322325 ISBN-13(EAN): 9789811322327 Издательство: Springer Рейтинг: Цена: 232910.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This new edited volume in the Springer Subcellular Biochemistry Series presents a comprehensive, state-of-the-art overview of the proteomics of peroxisomes derived from mammalian, Drosophila, fungal, and plant origin, and contains contributions from leading experts in the field. The development of sensitive proteomics and mass spectrometry technologies, combined with bioinformatics approaches now allow the identification of low-abundance and transient peroxisomal proteins and permits to identify the complete proteome of peroxisomes, with the consequent increase of our knowledge of the metabolic and regulatory networks of these important cellular organelles. The book lines-up with these developments and is organized in four sections including: (i) mass spectrometry-based organelle proteomics; (ii) prediction of peroxisomal proteomes; (iii) analysis of peroxisome proteome interaction networks; and (iv) peroxisomes in relation to other subcellular compartments. The editor Luis A. del R?o is Professor ad honorem of the Spanish National Research Council (CSIC) in the Group of Antioxidants, Free Radicals and Nitric Oxide in Biotechnology, Food and Agriculture, Department of Biochemistry and Cell & Molecular Biology of Plants, at the Estaci?n Experimental del Zaid?n, Granada, Spain. Del R?o’s research group focuses on the metabolism of reactive oxygen species (ROS), reactive nitrogen species (RNS) and antioxidants in plant peroxisomes, and the ROS- and RNS-dependent role of peroxisomes in plant cell signalling. The editor Michael Schrader is Professor of Cell Biology & Cytopathology in the Department of Biosciences at the University of Exeter, UK. Using mammalian peroxisomes as model organelles, Prof. Schrader and his team aim to unravel the molecular machinery and signalling pathways that mediate and regulate the formation, dynamics and abundance of these medically relevant cellular compartments.
Автор: Norbert Latruffe; Maurice Bugaut Название: Peroxisomes ISBN: 3642878091 ISBN-13(EAN): 9783642878091 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Luis A. del R?o Название: Peroxisomes and their Key Role in Cellular Signaling and Metabolism ISBN: 9401782903 ISBN-13(EAN): 9789401782906 Издательство: Springer Рейтинг: Цена: 130590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Peroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism.
Автор: Luis A. del R?o Название: Peroxisomes and their Key Role in Cellular Signaling and Metabolism ISBN: 9400768885 ISBN-13(EAN): 9789400768888 Издательство: Springer Рейтинг: Цена: 174150.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Peroxisomes are a class of ubiquitous and dynamic single membrane-bounded cell organelles, devoid of DNA, with an essentially oxidative type of metabolism.
Автор: Schrader Michael Название: Peroxisomes: Methods and Protocols ISBN: 149398344X ISBN-13(EAN): 9781493983445 Издательство: Springer Рейтинг: Цена: 107130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
1. Isolation of Peroxisomes from Rat Liver and Cultured Hepatoma Cells by Density Gradient Centrifugation
Andreas Manner and Markus Islinger
2. Isolation of Peroxisomes from Mouse Brain Using a Continuous Nycodenz Gradient: A Comparison to the Isolation of Liver and Kidney Peroxisomes
Miriam J. Schцnenberger and Werner J. Kovacs
3. Determining the Topology of Peroxisomal Proteins Using Protease Protection Assays
Tвnia Francisco, Ana F. Dias, Ana G. Pedrosa, Clбudia P. Grou, Tony A. Rodrigues, and Jorge E. Azevedo
4. Isolation of Native Soluble and Membrane-Bound Protein Complexes from Yeast Saccharomyces Cerevisiae
Tobias Hansen, Anna Chan, Thomas Schrцter, Daniel Schwerter, Wolfgang Girzalsky, and Ralf Erdmann
5. Method for Measurement of Peroxisomal Very Long-Chain Fatty Acid Beta-Oxidation and de novo C26:0 Synthesis Activity in Living Cells Using Stable-Isotope Labelled Docosanoic Acid
Malu-Clair van de Beek, Inge M.E. Dijkstra, and Stephan Kemp
6. Analysis of Plasmalogen Synthesis in Cultured Cells
Masanori Honsho and Yukio Fujiki
7. Transfection of Primary Human Skin Fibroblasts for Peroxisomal Studies
Janet Koster and Hans R. Waterham
8. siRNA-Mediated Silencing of Peroxisomal Genes in Mammalian Cells
Tina A. Schrader and Michael Schrader
9. Dual Reporter Systems for the Analysis of Translational Readthrough in Mammals
Julia Hofhuis, Severin Dieterle, Rosemol George, Fabian Schueren, and Sven Thoms
10. Cytochemical Detection of Peroxisomes in Light and Electron Microscopy with 3,3'-diaminobenzidine
H. Dariush Fahimi
11. Cryo-Immuno Electron Microscopy of Peroxisomal Marker Proteins
Karina Mildner and Dagmar Zeuschner
12. Detection and Immunolabelling of Peroxisomal Proteins
Tina Schrader, Markus Islinger, and Michael Schrader
13. Labelling of Peroxisomes for Live Cell Imaging in the Filamentous Fungus Ustilago Maydis
Sofia C. Guimaraes, Sreedhar Kilaru, Michael Schrader, and Martin Schuster
14. Quantitative Monitoring of Subcellular Redox Dynamics in Living Mammalian Cells Using RoGFP2-based Probes
Celien Lismont, Paul A. Walton, and Marc Fransen
15. KillerRed as a Tool to Study the Cellular Responses to Peroxisome-Derived Oxidative Stress
Marc Fransen and Chantal Brees
16. Determination of Peroxisomal pH in Living Mammalian Cells Using pHRed
Luis F. Godinho, and Michael Schrader
17. In Cellulo Approaches to Study Peroxisomal Protein Import - Yeast Immunofluorescence Microscopy
Tobias Hansen, Wolfgang Girzalsky, and Ralf Erdmann
18. Blue Native Page: Applications to Study Peroxisome Biogenesis
Kanji Okumoto, Shigehiko Tamura, and Yukio Fujiki
19. In Vitro PMP Import Analysis Using Cell-Free Synthesized PMP and Isolated Peroxisomes
Yuqiong Liu, Masanori Honsho, and Yukio Fujiki
20. Peroxisomal Membrane and Matrix Protein Import Using a Semi-Intact Mammalian Cell System
Kanji Okumoto, Masanori Honsho, Yuqiong Liu, and Yukio Fujiki
21. The Use of Glycosylation Tags as Reporters for Protein Entry into the Endoplasmic Reticulum in Yeast and Mammalian Cells
Judith Buentzel, and Sven Thoms
22. Detection of Ubiquitinated Peroxisomal Proteins in Yeast
Natasha Danda and Chris Williams
23. Assessing Pexophagy in Mammalian Cells
Shun-ichi Yamashita and Yukio Fujiki
24. Experimental Systems to Study Yeast Pexophagy
Shun-ichi Yamashita, Masahide O
Автор: A. Baker; I.A. Graham Название: Plant Peroxisomes ISBN: 9048160073 ISBN-13(EAN): 9789048160075 Издательство: Springer Рейтинг: Цена: 287890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In the two decades since the last comprehensive work on plant peroxisomes appeared, the scientific approaches employed in the study of plant biology have changed beyond all recognition.
Автор: Cecile Brocard; Andreas Hartig Название: Molecular Machines Involved in Peroxisome Biogenesis and Maintenance ISBN: 3709117879 ISBN-13(EAN): 9783709117873 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In eukaryotes, lipid metabolism requires the function of peroxisomes. These multitasking organelles are also part of species-specific pathways such as the glyoxylate cycle in yeast and plants or the synthesis of ether lipid in mammals. Proteins required for the biogenesis of peroxisomes typically assemble in large molecular complexes, which participate in membrane formation, protein transport, peroxisome duplication and - inheritance during cell division. Peroxisomal function is essential for life. Mutations in PEX genes, encoding for biogenesis factors, are often associated with lethal disorders. The association of peroxisomes with other organelles suggests an extensive participation in organellar crosstalk. This book represents a state-of-the-art review in the field of peroxisome research encompassing the cell and molecular biology of peroxisome biogenesis and its diseases, the protein complexes involved in this process and the modern technologies applied to study them. The book is intended for graduate students, researchers and lecturers in biochemistry, molecular and cell biology with a biomedical background.
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