Pharmacokinetics in Drug Development, Peter L. Bonate; Danny R. Howard

Автор: A. Yacobi; J.P. Skelly; Vinod P. Shah; L.Z. Benet
Название: Integration of Pharmacokinetics, Pharmacodynamics, and Toxicokinetics in Rational Drug Development
ISBN: 1475715226 ISBN-13(EAN): 9781475715224
Издательство: Springer
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Цена: 104480.00 T
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Описание: Proceedings of a conference sponsored by the American Association of Pharmaceutical Scientists, the U.S. Food and Drug Administration, and the American Society for Clinical Pharmacology and Therapeutics, held in Arlington, Virginia, April 24-26, 1991

Автор: Younggil Kwon
Название: Handbook of Essential Pharmacokinetics, Pharmacodynamics and Drug Metabolism for Industrial Scientists
ISBN: 147578693X ISBN-13(EAN): 9781475786934
Издательство: Springer
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Цена: 149060.00 T
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Описание: In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization.

Автор: Rowland
Название: Clinical Pharmacokinetics and Pharmacodynamics, 4e
ISBN: 0781750091 ISBN-13(EAN): 9780781750097
Издательство: Lippincott Williams & Wilkins
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Цена: 80080.00 T
Наличие на складе: Невозможна поставка.
Описание: Reflects the increasing body of knowledge linking the two concepts that explain the relationship between drug administration and drug response. This title also reflects the explosion in our understanding at the molecular and mechanistic levels of all the processes controlling the pharmacokinetics of drugs.

Автор: Schoenwald
Название: Pharmacokinetics in Drug Discovery and Development
ISBN: 1566769736 ISBN-13(EAN): 9781566769730
Издательство: Taylor&Francis
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Цена: 193950.00 T
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Описание: From basic principles to industrial and regulatory applications to clinical and research applications, this book reviews the subspecialties in the field of pharmacokinetics. It covers topics such as PK/PD approaches, clinical pharmacokinetic monitoring, population pharmacokinetics, and linear systems approaches.

Автор: Bonate
Название: Pharmacokinetics in Drug Development
ISBN: 3319390511 ISBN-13(EAN): 9783319390512
Издательство: Springer
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Цена: 167700.00 T
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Описание: In this volume, the specific challenges and problems facing the evaluation of new oncology agents are explored with regards to pharmacokinetic, pharmacodynamic modeling and clinical pharmacology development strategies. This book delivers, with an emphasis on the oncology therapeutic area, the goals set in the first three volumes: namely – to provide clinical pharmacologists practical insights for the application of pharmacology, pharmacokinetics and pharmacodynamics for new drug development strategies. Pharmacokinetic-pharmacodynamic concepts for tyrosine kinases, the evaluation of cardiac repolarization prolongation through QTc interval effects, efficacy- and safety-response analyses to support new drug approvals, clinical and preclinical tumor growth modeling, and flat- vs weight-based dose selection are showcased from an oncology clinical pharmacologist’s point-of-view. Oncology development strategies are surveyed for new FDA-approvals to identify patterns in expectations at time of first approval. The special considerations necessary to address combination drug development, metronomics, biosimilars and breakthrough therapies are also presented.

Автор: Bauer
Название: Applied Clinical Pharmacokinetics
ISBN: 0071794581 ISBN-13(EAN): 9780071794589
Издательство: McGraw-Hill
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Цена: 84650.00 T
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Описание: Helps you learn the clinical application of pharmacokinetics. This book delivers clear and clinically relevant coverage of drug dosing and drug monitoring that no other text can match. It offers the standardized techniques and approaches to patient-specific dosing, and information on pharmacokinetically monitored drugs.

Автор: Hedaya Mohsen A.
Название: Basic Pharmacokinetics, Second Edition
ISBN: 1439850739 ISBN-13(EAN): 9781439850732
Издательство: Taylor&Francis
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Цена: 102070.00 T
Наличие на складе: Нет в наличии.
Описание: Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. Accessible to a wide variety of readers, this volume demonstrates the quantitative pharmacokinetic relations and the interplay between pharmacokinetic parameters. Accompanying the book are downloadable resources with self-