Central Cholinergic Synaptic Transmission, Frotscher; Misgeld
Автор: Jacques Fantini Название: Brain Lipids in Synaptic Function and Neurological Disease ISBN: 0128001119 ISBN-13(EAN): 9780128001110 Издательство: Elsevier Science Рейтинг: Цена: 104410.00 T Наличие на складе: Невозможна поставка. Описание:
Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer's, Creutzfeldt-Jakob's and Parkinson's. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders.
Written to provide a "hands-on" approach for readers
Biochemical structures explained with molecular models, and molecular mechanisms explained with simple drawings
Step-by-step guide to memorize and draw lipid structures
Each chapter features a content summary, up-to-date references for additional study, and a key experiment with an explanation of the technique
Автор: Man Singh Название: Central Cholinergic Mechanisms and Adaptive Dysfunctions ISBN: 1468412205 ISBN-13(EAN): 9781468412208 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Although serious interest in studying the role of central cho- linergic processes in psychopathology is just beginning to emerge, experimental literature on the part played by cholinergic mechanisms in brain behavior.
Автор: Victor P. Whittaker Название: The Cholinergic Synapse ISBN: 3642732224 ISBN-13(EAN): 9783642732225 Издательство: Springer Рейтинг: Цена: 121110.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions by numerous experts
Автор: Giacobini Название: Brain Cholinergic System ISBN: 1841845752 ISBN-13(EAN): 9781841845753 Издательство: Taylor&Francis Рейтинг: Цена: 63280.00 T Наличие на складе: Нет в наличии. Описание: The cholinergic system has been recognized as playing an important role not only in several forms of dementia besides Alzheimer's Disease, but also in other CNS degenerative and psychiatric disorders. Following on from the success of two previous publications in the cholinergic field - Cholinesterases and Their Inhibitors and Butyrylcholinesterase: Its Function and Inhibitors - Doctor Ezio Giacobini and Professor Giancarlo Pepeu have prepared this comprehensive and timely volume, which will be useful to both clinical and pre-clinical specialists including neurologists, psychiatrists, neuropsychologists, neuropharmacologists and neurophysiologists, molecular neurobiologists and neurobiologists in general.
Автор: R. Tapia Название: Regulatory Mechanisms of Synaptic Transmission ISBN: 1468439707 ISBN-13(EAN): 9781468439700 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book, which originated in the presentations of a symposium sponsored by the Universidad Nacional Autonoma de Mexico, held in Mexico City on April 14-16, 1980, represents an attempt to analyze some of the most relevant aspects of synaptic transmission.
Автор: Peter V. Nguyen Название: Multidisciplinary Tools for Investigating Synaptic Plasticity ISBN: 1493959190 ISBN-13(EAN): 9781493959198 Издательство: Springer Рейтинг: Цена: 97820.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book highlights methods for probing the cellular and molecular mechanisms of synaptic plasticity in the nervous systems of vertebrate and invertebrate species. Includes strategies for studying plasticity, neural development and synaptogenesis and more.
Автор: Peter V. Nguyen Название: Multidisciplinary Tools for Investigating Synaptic Plasticity ISBN: 1627035168 ISBN-13(EAN): 9781627035163 Издательство: Springer Рейтинг: Цена: 97820.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book highlights methods for probing the cellular and molecular mechanisms of synaptic plasticity in the nervous systems of vertebrate and invertebrate species. Includes strategies for studying plasticity, neural development and synaptogenesis and more.
Автор: Maurizio Popoli; David Diamond; Gerard Sanacora Название: Synaptic Stress and Pathogenesis of Neuropsychiatric Disorders ISBN: 1493946323 ISBN-13(EAN): 9781493946327 Издательство: Springer Рейтинг: Цена: 130590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Recent studies show that changes in Glutamate/GABA synapses and related pathways may determine whether the synaptic plasticity that occurs as a response to stress is adaptive or maladaptive.
Автор: Marzia Malcangio Название: Synaptic Plasticity in Pain ISBN: 148998366X ISBN-13(EAN): 9781489983664 Издательство: Springer Рейтинг: Цена: 200260.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book focuses on emerging areas of synaptic plasticity and pain. It delineates anatomical circuits for pain in the dorsal horn, explores transmissions at the pain synapse, and discusses how synaptic plasticity can be monitored during pain transmission.
Автор: Michael R. Kreutz; Carlo Sala Название: Synaptic Plasticity ISBN: 3709117321 ISBN-13(EAN): 9783709117323 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book introduces current concepts of molecular mechanisms in synaptic plasticity, and offers a comprehensive overview of cutting-edge technology used to investigate the molecular dynamics of the synapses. Coverage includes clinical and applied aspects.
Автор: Sala, Carlo Название: Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and ISBN: 0128001097 ISBN-13(EAN): 9780128001097 Издательство: Elsevier Science Рейтинг: Цена: 104410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and Intellectual Disability provides the latest information on Autism spectrum disorders (ASDs), the lifelong neurodevelopmental disorders that present in early childhood and affect how individuals communicate and relate to others and their surroundings.
In addition, three quarters of ASD patients also manifest severe intellectual disability. Though certain genes have been implicated, ASDs remain largely a mystery, and research looking into causes and cellular deficits are crucial for better understanding of neurodevelopmental disorders.
Despite the prevalence and insidious nature of this disorder, this book remains to be an extensive resource of information and background on the state of current research in the field.
The book serves as a reference for this purpose, and discusses the crucial role synaptic activity plays in proper brain function. In addition, the volume discusses the neurodevelopmental synaptopathies and serves as a resource for scientists and clinicians in all biomedical science specialties. This research has been crucial for recent studies that have provided a rationale for the development of pharmacological agents able to counteract functional synaptic anomalies and potentially ameliorate some ASD symptoms.
Автор: Sreedharan Sajikumar Название: Synaptic Tagging and Capture ISBN: 1493955373 ISBN-13(EAN): 9781493955374 Издательство: Springer Рейтинг: Цена: 121890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: "Serves as a comprehensive introduction and overview of synaptic tagging and capture (STC) and covers the topic from molecular and cellular aspects to behavior. Circa 15 years ago the STC model was proposed to provide a conceptual basis for how short-term memories are transformed into long-term memories. Though the hypothesis remains unconfirmed due to technological limitations, the model is well consolidated and generally accepted in the field. Various researchers have investigated the cellular mechanisms for the formation of long-term memory using the STC model, but this is the first book-length treatments of STC. This volume features an introduction by Prof. Richard Morris and Prof. Cliff Abraham." --
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