Neuronal and Synaptic Dysfunction in Autism Spectrum Disorder and, Sala, Carlo

Автор: Jacques Fantini
Название: Brain Lipids in Synaptic Function and Neurological Disease
ISBN: 0128001119 ISBN-13(EAN): 9780128001110
Издательство: Elsevier Science
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Цена: 104410.00 T
Наличие на складе: Невозможна поставка.
Описание:

Lipids are the most abundant organic compounds found in the brain, accounting for up to 50% of its dry weight. The brain lipidome includes several thousands of distinct biochemical structures whose expression may greatly vary according to age, gender, brain region, cell type, as well as subcellular localization. In synaptic membranes, brain lipids specifically interact with neurotransmitter receptors and control their activity. Moreover, brain lipids play a key role in the generation and neurotoxicity of amyloidogenic proteins involved in the pathophysiology of neurological diseases. The aim of this book is to provide for the first time a comprehensive overview of brain lipid structures, and to explain the roles of these lipids in synaptic function, and in neurodegenerative diseases, including Alzheimer's, Creutzfeldt-Jakob's and Parkinson's. To conclude the book, the authors present new ideas that can drive innovative therapeutic strategies based on the knowledge of the role of lipids in brain disorders.

Автор: Lynne C. Weaver
Название: Autonomic Dysfunction After Spinal Cord Injury,152
ISBN: 0444519254 ISBN-13(EAN): 9780444519252
Издательство: Elsevier Science
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Цена: 224570.00 T
Наличие на складе: Поставка под заказ.
Описание: Intended for those who are involved in research and treatment of spinal cord injury, this book contains a compilation of what is known about bladder, cardiovascular, bowel and sexual dysfunction after spinal cord injury, as it relates to the changes within the autonomic nervous system control of these functions.

Автор: Gilliam
Название: Depression & Brain Dysfunction
ISBN: 1842142143 ISBN-13(EAN): 9781842142141
Издательство: Informa
Цена: 88960.00 T
Наличие на складе: Нет в наличии.
Описание: This volume is a scholarly reference to published research results on the neurobiology and neuroanatomy of depression and the association of depression with disorders of the central nervous system. The book reviews and discusses aspects of recent research on the underlying mechanisms of depression, including neurotransmitter dysregulation, hypothalamus-pituitary-adrenal axis abnormalities, and cellular resistance. Illustrated with tables, graphs, and charts, Depression and Brain Dysfunction is the first book to include the recent advances in functional neuroimaging of the structural and anatomical defects in patients with significant symptoms of depression.

Автор: Carl Faingold
Название: Neuronal Networks in Brain Function, CNS Disorders, and Therapeut
ISBN: 0124158048 ISBN-13(EAN): 9780124158047
Издательство: Elsevier Science
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Цена: 116780.00 T
Наличие на складе: Поставка под заказ.
Описание: Offers a review of what we know about neural networks. This book advances the understanding of: how the brain carries out important tasks via networks; how these networks interact in normal brain function; major mechanisms that control network function; and the interaction of the normal networks to produce more complex behaviors.

Автор: Reeve
Название: Mitochondrial Dysfunction in Neurodegenerative Disorders
ISBN: 3319286358 ISBN-13(EAN): 9783319286358
Издательство: Springer
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Цена: 125770.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This second edition brings together up-to-date contributionsfrom leaders in the field internationally on the various ways in whichmitochondrial dysfunction contributes to the pathogenesis of neurodegenerativediseases, including Parkinson’s disease, Alzheimer’s disease and multiplesclerosis. The reader is guided through the basic functions of mitochondria andthe mechanisms that lead to their dysfunction, and on to the consequences ofthis dysfunction for neuronal function before finishing with the modelling ofthese disorders and discussion of new potential therapeutic targets. Additional chapters have been added to the book to reflectadvances in the field and there are many new contributors and topics, includinghow mitochondria are degraded and the interaction of the mitochondria withpathologically relevant proteins. Mitochondrial Dysfunction in Neurodegenerative Disordersprovides an accessible, authoritative guide to this important area forneurologists; research and clinical neuroscientists; neuropathologists; andresidents with an interest in clinical research.