Pharmacokinetics in Drug Discovery and Development, Schoenwald

Автор: Bonate Peter, Howard Danny
Название: Pharmacokinetics in Drug Development / Regulatory and Development Paradigms (Volume 2)
ISBN: 0971176736 ISBN-13(EAN): 9780971176737
Издательство: Springer
Цена: 149030.00 T
Наличие на складе: Поставка под заказ.
Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.

Автор: Bonate Peter, Howard Danny
Название: Pharmacokinetics in Drug Development / Clinical Study Design and Analysis (Volume 1)
ISBN: 0971176744 ISBN-13(EAN): 9780971176744
Издательство: Springer
Рейтинг:
Цена: 204970.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These volumes are designed to be the most complete guide to pharmacokinetics (PK) and its role in drug development. Geared toward graduate level students and scientists in the areas of clinical pharmacology and PK, the volumes will fill a gap between the academic science and the practical application of that knowledge in drug development. Volume 1 discusses the role that PK plays in selected clinical study designs, including first-time-in-man, biopharmaceuticals, and special population studies. Volume 2 details the key regulatory and development paradigms in which PK supplements decision-making during drug development.

Автор: Alexander Vinks; Hartmut Derendorf; Johan Mouton (
Название: Fundamentals of Antimicrobial Pharmacokinetics and Pharmacodynamics
ISBN: 0387756124 ISBN-13(EAN): 9780387756127
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The reader will be introduced to various aspects of the fundamentals of antimicrobial pharmacodynamics, the integration of pharmacokinetics with pharmacodynamics for all major classes of antibiotics, and the translation of in vitro and animal model data to basic research and clinical situations in humans.

Автор: Tozer
Название: Introduction to Pharmacokinetics and Pharmacodynamics: The Quantitative Basis of Drug Therapy
ISBN: 0781751497 ISBN-13(EAN): 9780781751490
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 49190.00 T
Наличие на складе: Поставка под заказ.
Описание: This unique text helps students and healthcare professionals master the fundamentals of pharmacokinetics and pharmacodynamics. Written by distinguished international experts, it provides readers with an introduction to the basic principles underlying the establishment and individualization of dosage regimens and their optimal use in drug therapy. Up-to-date examples featuring currently prescribed drugs illustrate how pharmacokinetics and pharmacodynamics relate to contemporary drug therapy. Study problems at the end of each chapter help students and professionals gain a firm grasp of the material covered within the text.

Автор: Burton
Название: Applied Pharmacokinetics and Pharmacodynamics
ISBN: 0781744318 ISBN-13(EAN): 9780781744317
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 51480.00 T
Наличие на складе: Невозможна поставка.
Описание: "The definitive advanced-level clinical pharmacokinetics text is now in its Fourth Edition, with new emphasis on the relationship between pharmacokinetics and pharmacodynamics. Written by 70 leading researchers and practitioners, this book is a rigorous yet practical text on the application of pharmacokinetic methods, pharmacodynamic principles, and pharmacotherapeutic data for optimal, individualized drug therapy.

Автор: Bonate
Название: Pharmacokinetics in Drug Development
ISBN: 3319390511 ISBN-13(EAN): 9783319390512
Издательство: Springer
Рейтинг:
Цена: 167700.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this volume, the specific challenges and problems facing the evaluation of new oncology agents are explored with regards to pharmacokinetic, pharmacodynamic modeling and clinical pharmacology development strategies. This book delivers, with an emphasis on the oncology therapeutic area, the goals set in the first three volumes: namely – to provide clinical pharmacologists practical insights for the application of pharmacology, pharmacokinetics and pharmacodynamics for new drug development strategies. Pharmacokinetic-pharmacodynamic concepts for tyrosine kinases, the evaluation of cardiac repolarization prolongation through QTc interval effects, efficacy- and safety-response analyses to support new drug approvals, clinical and preclinical tumor growth modeling, and flat- vs weight-based dose selection are showcased from an oncology clinical pharmacologist’s point-of-view. Oncology development strategies are surveyed for new FDA-approvals to identify patterns in expectations at time of first approval. The special considerations necessary to address combination drug development, metronomics, biosimilars and breakthrough therapies are also presented.

Автор: Riviere E Jim, Wang J Paul, Sackner-Bernstein Jona
Название: Comparative Pharmacokinetics
ISBN: 081382138X ISBN-13(EAN): 9780813821382
Издательство: Wiley
Рейтинг:
Цена: 42230.00 T
Наличие на складе: Невозможна поставка.
Описание: Presents an overview of pharmacokinetics. This work explains the scientific data and mathematical models of the discipline within the context of biological reality. It explains and assesses both mechanistic, compartmental models, and the empirical noncompartmental models, considering strengths and weaknesses of each.

Автор: Bauer
Название: Handbook of clinical pharmacokinetics
ISBN: 007142542X ISBN-13(EAN): 9780071425421
Издательство: McGraw-Hill
Рейтинг:
Цена: 42310.00 T
Наличие на складе: Поставка под заказ.
Описание: Designed for pharmacists and clinicians responsible for adjusting drug dosages based on the patient blood serum concentrations and other parameters, this indispensable, portable reference offers a variety of ways to perform pharmacokinetic calculations. It also features calculation methods, algorithms for choosing the best calculation method, and case studies.

Автор: Shargel
Название: Applied Biopharmaceutics & Pharmacokinetics
ISBN: 0071240055 ISBN-13(EAN): 9780071240055
Издательство: McGraw-Hill
Цена: 28590.00 T
Наличие на складе: Поставка под заказ.
Описание: The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.