Basic Pharmacokinetics, Second Edition, Hedaya Mohsen A.

Автор: Hedaya, Mohsen A.
Название: Basic Pharmacokinetics
ISBN: 036775214X ISBN-13(EAN): 9780367752149
Издательство: Taylor&Francis
Цена: 148010 T

Автор: Bonate
Название: Pharmacokinetics in Drug Development
ISBN: 3319390511 ISBN-13(EAN): 9783319390512
Издательство: Springer
Рейтинг:
Цена: 167700.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this volume, the specific challenges and problems facing the evaluation of new oncology agents are explored with regards to pharmacokinetic, pharmacodynamic modeling and clinical pharmacology development strategies. This book delivers, with an emphasis on the oncology therapeutic area, the goals set in the first three volumes: namely – to provide clinical pharmacologists practical insights for the application of pharmacology, pharmacokinetics and pharmacodynamics for new drug development strategies. Pharmacokinetic-pharmacodynamic concepts for tyrosine kinases, the evaluation of cardiac repolarization prolongation through QTc interval effects, efficacy- and safety-response analyses to support new drug approvals, clinical and preclinical tumor growth modeling, and flat- vs weight-based dose selection are showcased from an oncology clinical pharmacologist’s point-of-view. Oncology development strategies are surveyed for new FDA-approvals to identify patterns in expectations at time of first approval. The special considerations necessary to address combination drug development, metronomics, biosimilars and breakthrough therapies are also presented.

Автор: Schoenwald
Название: Pharmacokinetics in Drug Discovery and Development
ISBN: 1566769736 ISBN-13(EAN): 9781566769730
Издательство: Taylor&Francis
Рейтинг:
Цена: 193950.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: From basic principles to industrial and regulatory applications to clinical and research applications, this book reviews the subspecialties in the field of pharmacokinetics. It covers topics such as PK/PD approaches, clinical pharmacokinetic monitoring, population pharmacokinetics, and linear systems approaches.