High Content Screening, Paul A. Johnston; Oscar Joseph Trask

Автор: Haney
Название: High Content Screening - Science, Techniques, and Applications +CD
ISBN: 047003999X ISBN-13(EAN): 9780470039991
Издательство: Wiley
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Цена: 161510.00 T
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Описание: The authoritative reference on HCS in biological and pharmaceutical research High Content Screening (HCS) has been a leading methodology in toxicology studies for years. Recent advances have broadened the range of applications to encompass new areas.

Автор: D. Lansing Taylor
Название: High Content Screening
ISBN: 1617377465 ISBN-13(EAN): 9781617377464
Издательство: Springer
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Цена: 172350.00 T
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Описание: There has always been some tension between proponents of hypothesis-driven and discovery-driven research in the broad field of life sciences. However, the success of the human genome project, a discovery-driven research approach, has opened the door to adding other types of discovery-driven research to a continuum of research approaches.

Автор: Bhunia, A K
Название: High Throughput Screening for Food Safety Assessment
ISBN: 0081013833 ISBN-13(EAN): 9780081013830
Издательство: Elsevier Science
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Цена: 213350.00 T
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Описание: Recent advances in array-based detectors and imaging technologies have provided high throughput systems that can operate within a substantially reduced timeframe and other techniques that can detect multiple contaminants at one time. These technologies are revolutionary in terms of food safety assessment in manufacturing, and will also have a significant impact on areas such as public health and food defence. This book summarizes the latest research and applications of sensor technologies for online and high throughput screening of food. . . The book first introduces high throughput screening strategies and technology platforms, and discusses key issues in sample collection and preparation. The subsequent chapters are then grouped into four sections: Part I reviews biorecognition techniques; Part II covers the use of optical biosensors and hyperspectral imaging in food safety assessment; Part III focuses on electrochemical and mass-based transducers; and finally Part IV deals with the application of these safety assessment technologies in specific food products, including meat and poultry, seafood, fruits and vegetables.

Автор: Janzen
Название: High Throughput Screening
ISBN: 1493936719 ISBN-13(EAN): 9781493936717
Издательство: Springer
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Цена: 111790.00 T
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Описание: This third edition volumeexpands on the previous editions both by presenting more detailed protocols forthe techniques described in the first and second editions of High ThroughputScreening: Methods and Protocolsand by covering important new procedures. The first chapter ofthis book provides an overview of important assay development techniques, whilethe rest of the chapters detail how to develop and execute screens at whateverthroughput the user needs. Some chapter examples are: structure-based virtualscreening, high throughput screening using mass spectrometry, identification of state-dependentblockers for voltage gated calcium channels, bioluminescence resonanceenergy transfer platform to monitor protein-protein interactions in live cells,high throughput flow cytometry, and application of imaging-based assays in microplate formats for highcontent screening. Written in the highly successful Methods in MolecularBiology series format, chapters include introductions to their respectivetopics, lists of the necessary materials and reagents, step-by-step, readilyreproducible laboratory protocols, and tips on troubleshooting and avoidingknown pitfalls.Cutting edge and thorough, High Throughput Screening: Methods and Protocols,Third Edition, is a valuable resource for anyone who is interested in HTSresearch.

Автор: Richard L Bell
Название: Animal Models for Medications Screening to Treat Addiction,126
ISBN: 0128040130 ISBN-13(EAN): 9780128040133
Издательство: Elsevier Science
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Цена: 162820.00 T
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Описание:

"Animal Models for Medications Screening to Treat Addiction," the latest volume in the "International Review of Neurobiology" series, provides a comprehensive overview of the state-of-the-art research on the topic. It reviews the current knowledge and understanding in the field, presenting a starting point for researchers and practitioners entering the field.
Brings together information on the current state of medication development for drug addiction using animal modelsContains comprehensive descriptions of various models associated with many forms of drug addictionAdds new information for translational research in the field of drug addiction

Автор: R.C. Bird; Bruce F. Smith
Название: Genetic Library Construction and Screening
ISBN: 364247733X ISBN-13(EAN): 9783642477331
Издательство: Springer
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Цена: 46570.00 T
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Описание: These include cDNA cloning and transcript mapping, mutagenesis as well as the cloning of very long transcripts and protocols using limiting amounts of total RNA. Further chapters describe approaches to subtractive cloning technologies as well as novel specialized expression cloning and library screening strategies.

Автор: Taro Noguchi
Название: Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Products
ISBN: 9811066221 ISBN-13(EAN): 9789811066221
Издательство: Springer
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Цена: 102480.00 T
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Описание: This thesis mainly describes the development of a screening process for a mirror-image library of chiral natural products. It demonstrates how, by using mirror-image proteins for the screening of available natural products, unavailable mirror-image isomers of natural products can be screened in a mirror process.

Автор: E Scott Sills
Название: Screening the Single Euploid Embryo
ISBN: 3319357670 ISBN-13(EAN): 9783319357676
Издательство: Springer
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Цена: 139750.00 T
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Описание: Intended for readers with a background in fertility medicine as well as those less familiar with IVF, this comprehensive work presents an update on preimplantation genetic testing to enable single embryo transfer (SET).