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Advances in Nanomedicine for the Delivery of Therapeutic Nucleic, Nimesh, Surendra


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Автор: Nimesh, Surendra
Название:  Advances in Nanomedicine for the Delivery of Therapeutic Nucleic
Издательство: Elsevier Science
Классификация:
ISBN: 0081005571
ISBN-13(EAN): 9780081005576
Обложка/Формат: Hardback
Страницы: 300
Вес: 0.54 кг.
Дата издания: 01.06.2017
Серия: Biomedicine
Язык: English
Размер: 229 x 152 x 16
Читательская аудитория: Professional & vocational
Рейтинг:
Поставляется из: Англии
Описание:

Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance.

The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc.

  • Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies
  • Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc.
  • Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field

Дополнительное описание:


Nanomedicine for Drug Delivery and Therapeutics

Автор: Mishra
Название: Nanomedicine for Drug Delivery and Therapeutics
ISBN: 1118414098 ISBN-13(EAN): 9781118414095
Издательство: Wiley
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Цена: 102540 T
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Описание: This book describes a broad area of nanomedicine which involves mainly applications, diseases, and diagnostics. The comprehensive coverage provides researchers, academics, and health specialists with a great tool, that includes techniques applicable to various uses.

Nanomedicine in Diagnostics

Автор: Rozlosnik N.
Название: Nanomedicine in Diagnostics
ISBN: 1578087384 ISBN-13(EAN): 9781578087389
Издательство: Taylor&Francis
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Цена: 66070 T
Наличие на складе: Есть
Описание: Research on new sensing concepts has opened the door to a wide variety of microsystems for clinical applications. Such devices are extremely useful for delivering diagnostic information in a fast, simple, and low cost fashion. This book is one of the first to focus on the use of nanotechnology in diagnostics. Designed as a broad survey of the field, this book combines contributions by international experts from divergent fields of study ranging from single molecule diagnostics to cell based systems.

Nanomedicine, An Issue of Medical Clinics,91-5

Автор: Chiming Wei
Название: Nanomedicine, An Issue of Medical Clinics,91-5
ISBN: 141603529X ISBN-13(EAN): 9781416035299
Издательство: Elsevier Science
Цена: 41170 T
Наличие на складе: Невозможна поставка.


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