Nanomedicine for Drug Delivery and Therapeutics, Mishra
Автор: Rozlosnik N. Название: Nanomedicine in Diagnostics ISBN: 1578087384 ISBN-13(EAN): 9781578087389 Издательство: Taylor&Francis Рейтинг: Цена: 94380 T Наличие на складе: Есть Описание: Research on new sensing concepts has opened the door to a wide variety of microsystems for clinical applications. Such devices are extremely useful for delivering diagnostic information in a fast, simple, and low cost fashion. This book is one of the first to focus on the use of nanotechnology in diagnostics. Designed as a broad survey of the field, this book combines contributions by international experts from divergent fields of study ranging from single molecule diagnostics to cell based systems.
Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance.
The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc.
Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies
Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc.
Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field
Автор: Stergios Logothetidis Название: Nanomedicine and Nanobiotechnology ISBN: 3642432662 ISBN-13(EAN): 9783642432668 Издательство: Springer Рейтинг: Цена: 78360 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book presents laboratory, scientific and clinical aspects of nanomaterials used for medical applications in regenerative medicine, dentistry and pharmacy. Examines compatibility assessment, and offers advanced nondestructive nano-precision techniques.
Автор: Hehenberger Название: Nanomedicine, From Science To Busin ISBN: 9814613762 ISBN-13(EAN): 9789814613767 Издательство: Taylor&Francis Рейтинг: Цена: 55170 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: By covering the science, business, and societal impact of nanomedicine, this book makes a strong case for funding of basic research, for effective translation of scientific breakthroughs into clinical care of patients, and for close collaboration among all stakeholders in the healthcare ecosystem. It covers the underlying science and technology of nanomedicine in detail to help understand the great promise of nanomedicine across all disease areas. Although rich and deep in content, the book attempts to introduce the topic of nanomedicine to a wide audience. Scientific jargon is avoided and advanced terms and concepts are explained from the ground up, whenever first introduced. The book defines nanomedicine in a broad sense, including diagnostic devices such as DNA sequencing and molecular imaging, and new therapeutic options based on targeted drug delivery, regenerative medicine, immunotherapeutics, the creation of implanted devices such as continuous glucose monitors and deep brain stimulators, and even the 3D printing of new human organs. It also covers the returns of investment in global scientific projects, such as the Human Genome Project, and the historic and emerging importance of philanthropic foundations.
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