Nanomedicine, An Issue of Medical Clinics,91-5, Chiming Wei
Автор: Mishra Название: Nanomedicine for Drug Delivery and Therapeutics ISBN: 1118414098 ISBN-13(EAN): 9781118414095 Издательство: Wiley Рейтинг: Цена: 136710.00 T Наличие на складе: Есть Описание: This book describes a broad area of nanomedicine which involves mainly applications, diseases, and diagnostics. The comprehensive coverage provides researchers, academics, and health specialists with a great tool, that includes techniques applicable to various uses.
Автор: Nimesh, Surendra Название: Advances in Nanomedicine for the Delivery of Therapeutic Nucleic ISBN: 0081005571 ISBN-13(EAN): 9780081005576 Издательство: Elsevier Science Рейтинг: Цена: 190890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance.
The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc.
Provides a complete overview of the applicatiosn of nanomedicine in the delivery of nucleic acids, from characterization of nanoparticles, to in vitro and in vivo studies
Discusses delivery issues of less well explored nucleic acids, like PNAs, Ribozymes, DNAzymes, etc.
Summarizes the current state of research in nucleic acid delivery and underscores the future of nanomedicine in this field
Автор: Piyush Kumar; Rohit Srivastava Название: Nanomedicine for Cancer Therapy ISBN: 3319458256 ISBN-13(EAN): 9783319458250 Издательство: Springer Рейтинг: Цена: 51230.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This Brief focuses on the cancer therapy available till date, from conventional drug delivery to nanomedicine in clinical trial. In addition, it reports on future generation based nanotherapeutics and cancer theranostic agent for effective therapeutic diagnosis and treatment.
Автор: Christine Vauthier; Gilles Ponchel Название: Polymer Nanoparticles for Nanomedicines ISBN: 3319414194 ISBN-13(EAN): 9783319414195 Издательство: Springer Рейтинг: Цена: 204970.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Preface.- Introduction Part I: Polymer nanoparticles for in vivo applications: Progress on preparation methods and future challenges.- Nanoprecipitation process: From particlepreparation to in vivo applications.- Targeted Theragnostic Nanoparticles via Flash Nanoprecipitation: Principles of Materials Selection.- Preparation of polymer nanoparticles by the emulsification-solvent evaporation method: from Vanderhoff s pioneer approach to recent adaptations.- Methods for the preparation of nanoparticles by polymerization.- Shape-controlled nanoparticles for drug delivery and targeting applications.- Physicochemical characterization of polymer nanoparticles: Challenges and present limitations.- Imaging polymer nanoparticles by means of transmission and scanning electron microscopy techniques.- Evaluating the interactions between proteins and components of the immune system with polymer nanoparticles.- Investigating interactions between nanoparticles and cells: internalization and intracellular trafficking.- Characterization of mucoadhesive interactions between nanoparticles and epithelial membranes.- Designing polymer nanoparticle nanomedicines: potential applications and challenges.- Selecting and designing polymers suitable for nanoparticles manufacturing.- Associating Drugs with Polymer Nanoparticles: A Challenge.- Drug delivery by nanoparticles: The Challenge of Controlled Release and Evaluation.- Interaction between nanoparticles and plasma proteins: effects on nanoparticle biodistribution and toxicity.- Toxicological aspects of polymer nanoparticles.- Theranostics: In Vivo.- Nanomedicines -A scientific toy or an emerging market?.- Regulatory perspective on the development of polymeric nanomaterials.
Автор: Igarashi Название: Nanomedicines And Nanoproducts ISBN: 1498706622 ISBN-13(EAN): 9781498706629 Издательство: Taylor&Francis Рейтинг: Цена: 193950.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body provides a detailed overview of the disposition of nanoproducts within the body, with a special focus on the respiratory and olfactory routes of nanoproduct administration, buccal exposure and the ingestion of nanoproducts, the integumentary system (formed by the skin, hair, nails, and associated glands), the ocular route, the systemic route, and toxicology as it relates to the nanoscale world.
Offering an interdisciplinary, big-picture view of the current and future state of nanotechnology, this book:
Identifies key points for the entry of nanoproducts, nanomedicines, and other nanoscale structures into the body
Reviews the bodily administration and subsequent disposition of nanoproducts via various exposure routes
Describes the intravenous route of administration for the therapeutic management of ocular disease
Discusses practical nanoproduct and nanomedicine applications, disposition, and toxicology
Summarizes various toxicological principles and the testing of nanoproducts
Nanomedicines and Nanoproducts: Applications, Disposition, and Toxicology in the Human Body addresses the scope of practical nanoparticle applications in academic research as well as industrial investigation, where "practical" is defined as advantageous in all aspects of nanoproduct disposition, efficacy, and toxicology. The book's goal is to introduce potentially beneficial applications and exciting topics regarding nanoproducts to a variety of professional and general readers.
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