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Biomarkers as Targeted Herbal Drug Discovery, 


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Цена: 84710.00T
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Название:  Biomarkers as Targeted Herbal Drug Discovery
ISBN: 9781774637876
Издательство: Taylor&Francis
Классификация:








ISBN-10: 1774637871
Обложка/Формат: Paperback
Страницы: 336
Вес: 0.67 кг.
Дата издания: 25.09.2023
Иллюстрации: 27 tables, black and white; 14 line drawings, color; 10 line drawings, black and white; 6 halftones, black and white; 14 illustrations, color; 16 illustrations, black and white
Размер: 234 x 156
Подзаголовок: A pharmacological approach to nanomedicines
Рейтинг:
Поставляется из: Европейский союз

Advances in Cancer Biomarkers

Автор: Roberto Scatena
Название: Advances in Cancer Biomarkers
ISBN: 9402404201 ISBN-13(EAN): 9789402404203
Издательство: Springer
Рейтинг:
Цена: 156720.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

Prelims.- I Generality.- II Tumor markers-a critical revision.- Enzymes.- Hormones.- Oncofetal proteins.- Cytokeratins.- Carbohydrate markers.- Blood group antigens.- Genetic markers.- Various protein markers.- III Perspectives.- The role of Circulating tumor Cells as tumor markers.- Index.


Biomarkers as Targeted Herbal Drug Discovery

Название: Biomarkers as Targeted Herbal Drug Discovery
ISBN: 1771889020 ISBN-13(EAN): 9781771889025
Издательство: Taylor&Francis
Рейтинг:
Цена: 141890.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Biomarkers as Targeted Herbal Drug Discovery: A Pharmacological Approach to Nanomedicines discusses phytoconstituent-based nanotherapeutics with applications for some specific health issues, such as arthritis, leishmanicidal, cardiovascular diseases, cancer, ocular disorders, etc.

Encyclopedia of Drug Discovery and Development: Volume II (Tools, Methods, Biomarkers and Drug Discovery)

Автор: Burnett Ned
Название: Encyclopedia of Drug Discovery and Development: Volume II (Tools, Methods, Biomarkers and Drug Discovery)
ISBN: 1632421372 ISBN-13(EAN): 9781632421371
Издательство: Неизвестно
Цена: 159860.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Biomarkers in Drug Discovery and Disease Diagnosis

Автор: Lambert Holly
Название: Biomarkers in Drug Discovery and Disease Diagnosis
ISBN: 1632428350 ISBN-13(EAN): 9781632428356
Издательство: Неизвестно
Рейтинг:
Цена: 155570.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.

Redox Signaling and Biomarkers in Ageing

Автор: Зakatay Ufuk
Название: Redox Signaling and Biomarkers in Ageing
ISBN: 3030849643 ISBN-13(EAN): 9783030849641
Издательство: Springer
Рейтинг:
Цена: 130430.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book aims to present the age-related alterations in redox signaling networks and their diagnostic biomarkers in aging cells using multidisciplinary approach.

Biomarkers, Diagnostics and Precision Medicine in the Drug Industry

Автор: Halim, Abdel
Название: Biomarkers, Diagnostics and Precision Medicine in the Drug Industry
ISBN: 0128161213 ISBN-13(EAN): 9780128161210
Издательство: Elsevier Science
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Цена: 132500.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

The high failure rate in the pharmaceutical industry has positioned biomarkers and personalized medicine in the frontline as possible solutions. If executed right, biomarkers and companion diagnostics (CDx) can potentially help the drug industry enhance the probability of success, accelerating time to market, and, more importantly, benefit patients by supporting accurate diagnosis and selection of the most effective and least toxic therapies. Biomarkers, Diagnostics, and Precision Medicine in the Drug Industry aims to examine the challenges and limitations in biomarkers and laboratory tests. It also offers advice on best practices to ensure proper application of biomarkers and bridges the gap between diagnostic business development claims and real-life deliverables. The book covers biomarkers for different purposes, provides examples from different technologies which includes standard-of-care approved assays as well as for-investigational-use and for-research-use-only assays. It also includes new data for biomarkers in different therapeutic indications and offers case studies and practical examples. Biomarkers, Diagnostics, and Precision Medicine in the Drug Industry serves as a reference to drug developers, IVD providers, healthcare givers, academics, and researchers for best practices to help increase the probability of success.

  • Provides the unique insight of an expert with extensive experience in diagnostics and clinical laboratory on one side and drug discovery and development on the other side
  • Addresses the challenges of drug development and precision medicine and suggests how to eliminate or mitigate these challenges through better utilization of biomarkers and diagnostics in drug development and patient management
  • Features case studies and real-life examples from different classes of biomarkers on different platforms for different therapeutic areas

Biomarkers for Alzheimer`s Disease Drug Development

Автор: Perneczky
Название: Biomarkers for Alzheimer`s Disease Drug Development
ISBN: 1493977032 ISBN-13(EAN): 9781493977031
Издательство: Springer
Рейтинг:
Цена: 74530.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

PART I: The need for Alzheimer's Disease Biomarkers

1. Epidemiology of Dementia: The Burden on Society, the Challenges for Research

Frank J. Wolters and M. Arfan Ikram

2. Population-based Approaches to Alzheimer's Disease Prevention

Robert Perneczky

3. Systems Biology Methods for Alzheimer's Disease Research towards Molecular Signatures, Subtypes and Stages and Precision Medicine. Application in Cohort Studies and Trials

Juan I. Castrillo, Simone Lista, Harald Hampel, and Craig W. Ritchie

PART II: Innovative Approaches to Cerebrospinal Fluid Biomarker Discovery

4. CSF Lipidomics Analysis: High-Resolution Mass Spectrometry Analytical Platform

Paul L. Wood and Randall L. Woltjer

5. CSF N-glycomics using MALDI MS Techniques in Alzheimer's Disease

Angelo Palmigiano, Angela Messina, Rosaria Ornella Bua, Rita Barone, Luisa Sturiale, Mario Zappia, and Domenico Garozzo

6. MicroRNA Profiling of Alzheimer's Disease Cerebrospinal Fluid Johannes Denk and Holger Jahn

Part III: Novel Blood-based Biomarkers

7. Validation of a Chemiluminescence Immunoassay for Measuring Amyloid-β in Human Blood Plasma

Jonathan Vogelgsang, Jens Wiltfang, and Hans-W. Klafki

8. Mass Spectrometry-based Metabolomic Multiplatform for Alzheimer's Disease Research

Raъl Gonzбlez-Domнnguez, Бlvaro Gonzбlez-Domнnguez, Ana Sayago, and Бngeles Fernбndez-Recamales

9. Blood-based Biomarker Screening with Agnostic Biological Definitions for an Accurate Diagnosis within the Dimensional Spectrum of Neurodegenerative Diseases

Filippo Baldacci, Simone Lista, Sid E. O'Bryant, Roberto Ceravolo, Nicola Toschi, and Harald Hampel,

Part IV: Magnetic Resonance Imaging Methods

10. Functional Magnetic Resonance Imaging in Alzheimer' Disease Drug Development

Stefan Holiga, Ahmed Abdulkadir, Stefan Klцppel, and Juergen Dukart

11. Neuroimaging Methods for MRI Analysis in CSF Biomarkers Studies

Carles Falcon, Grйgory Operto, Josй Luis Molinuevo, and Juan Domingo Gispert

12. Hybrid PET-MRI in Alzheimer's Disease Research

Ismini C. Mainta, Maria I. Vargas, Sara Trombella, Giovanni B. Frisoni, Paul G. Unschuld, Valentina Garibotto

Part V: Molecular Imaging Approaches

13. Amyloid PET Imaging: Standardization and Integration with Other Alzheimer Disease Biomarkers

Silvia Morbelli and Matteo Bauckneht

14. The use of 18F-FDG PET in the Diagnostic Workup of Alzheimer's Dementia

Marion M. Ortner

15. Quantification of Tau Load in Alzheimer's Disease Clinical Trials Using Positron Emission Tomography

Tessa Timmers, Bart N.M. van Berckel, Adriaan Lammertsma, and Rik Ossenkoppele

16. Imaging Neuroinflammation: Quantification of Astrocytosis in a Multitracer PET Approach

Elena Rodriguez-Vieitez and Agneta Nordberg

Part VI: Neuropathology

17. Unbiased Lipidomics and Metabolomics of Human Brain Samples

Giuseppe Astarita, Matteo Stocchero, and Giuseppe Paglia

18. Neuropathological Assessment as an Endpoint in Clinical Trial Design

Steve Gentleman and Alan King Lun Liu

Part VII Genomic Methods

19. Analysis of micro-RNA Expression by qPCR on a Microfluidics Platform for Alzheimer's Disease Biomarker Discovery

Petros Takousis

20. Telomere length shortening in Alzheimer's disease - procedures for a causal investigation using single nucleotide polymorphisms in a Mendelian Randomization study
Yiqiang Zhan,

Biomarkers for Alzheimer`s Disease Drug Development

Автор: Robert Perneczky
Название: Biomarkers for Alzheimer`s Disease Drug Development
ISBN: 1493992627 ISBN-13(EAN): 9781493992621
Издательство: Springer
Рейтинг:
Цена: 74530.00 T
Наличие на складе: Поставка под заказ.
Описание: This volume aims to build a new generation of experts with a broader understanding of key topics in the Alzheimer’s disease field. Chapters guide readers through innovative approaches to the discovery of novel biomarkers in cerebrospinal fluid, innovation in blood-based biomarkers, a comprehensive overview of magnetic resonance imaging and molecular imaging approaches and their value for developing drugs for Alzheimer’s disease, cutting-edge developments in neuropathology and their relevance for Alzheimer’s disease trials, novel genomic strategies for biomarker development, and related topics including neuropsychological testing and advanced analytical methods.Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Biomarkers for Alzheimer's Disease Drug Development aims to ensure successful results in the further study of this vital field.

Therapeutic Drug Monitoring

Автор: Dasgupta, Amitava
Название: Therapeutic Drug Monitoring
ISBN: 0123854679 ISBN-13(EAN): 9780123854674
Издательство: Elsevier Science
Рейтинг:
Цена: 140360.00 T
Наличие на складе: Поставка под заказ.
Описание: Features topics such as the monitoring of classical and newer drugs, pharmacogenomics and the application of biomarkers in therapeutic drug monitoring. This title presents advanced techniques used for proper determination of blood levels and the clinical utility of therapeutic drug monitoring of contemporary drugs.

Biomarkers in Clinical Drug Development

Автор: Bloom, John
Название: Biomarkers in Clinical Drug Development
ISBN: 0824740262 ISBN-13(EAN): 9780824740269
Издательство: Taylor&Francis
Рейтинг:
Цена: 183750.00 T
Наличие на складе: Нет в наличии.

Application of Omic Techniques to Identify New Biomarkers and Drug Targets for COVID-19

Автор: Guest
Название: Application of Omic Techniques to Identify New Biomarkers and Drug Targets for COVID-19
ISBN: 3031280113 ISBN-13(EAN): 9783031280115
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The COVID-19 pandemic caused by the SARS-CoV-2 virus has affected nearly every country and territory in the world. Although worldwide vaccination efforts have reduced the risk of serious disease outcomes, disparities in distribution have led to multiple waves of SARS-CoV-2 outbreaks and the emergence of variants of concern, some of which have enhanced infectivity and ability to evade existing vaccines. Hence there is an increasing interest in understanding the evolution of viruses like SARS-CoV-2, as well as improving our capacity to effectively current and manage future pandemics. This new volume reviews the most effective omic techniques for increasing our understanding of COVID-19, to improve diagnostics, prognostics, and genomic surveillance, and to facilitate development of effective treatments and vaccines. Chapters are written by an international team of experts and explore methods in the areas of genomics, transcriptomics, proteomics, and metabolomics. Techniques used to assess physiological function at the molecular level and artificial intelligence approaches used for more effective validation and translation of biomarker candidates into clinical use are also discussed. This book is an excellent resource for researchers studying biomarkers, virology, metabolic diseases, and infectious diseases, as well as clinical scientists, physicians, drug company scientists, and healthcare workers.

Immunotherapy and Biomarkers in Neurodegenerative Disorders

Автор: Martin Ingelsson; Lars Lannfelt
Название: Immunotherapy and Biomarkers in Neurodegenerative Disorders
ISBN: 1493935585 ISBN-13(EAN): 9781493935581
Издательство: Springer
Рейтинг:
Цена: 130430.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: With a focus on Alzheimer`s disease, the firstsections of the book examine immunotherapeutic approaches for theaforementioned disease as well as for Parkinson`s disease and Huntington`s disease,amongst others.


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