Hydrogen Sulfide In Redox Biology Part B,555, Cadenas,Enrique

Автор: Enrique Cadenas
Название: Hydrogen Sulfide in Redox Biology Part A,554
ISBN: 0128015128 ISBN-13(EAN): 9780128015124
Издательство: Elsevier Science
Рейтинг:
Цена: 154960.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: These new volumes of Methods in Enzymology (554 and 555) on Hydrogen Sulfide Signaling continue the legacy established by previous volumes on another gasotransmitter, nitric oxide (Methods in Enzymology volumes 359, 396, 440, and 441), with quality chapters authored by leaders in the field of hydrogen sulfide research. These volumes of Methods in Enzymology were designed as a compendium for hydrogen sulfide detection methods, the pharmacological activity of hydrogen sulfide donors, the redox biochemistry of hydrogen sulfide and its metabolism in mammalian tissues, the mechanisms inherent in hydrogen sulfide cell signaling and transcriptional pathways, and cell signaling in specific systems, such as cardiovascular and nervous system as well as its function in inflammatory responses. Two chapters are also devoted to hydrogen sulfide in plants and a newcomer, molecular hydrogen, its function as a novel antioxidant.

Автор: Singh, Samiksha
Название: Hydrogen Sulfide In Plant Biology
ISBN: 0323858627 ISBN-13(EAN): 9780323858625
Издательство: Elsevier Science
Рейтинг:
Цена: 167310.00 T
Наличие на складе: Нет в наличии.
Описание: Digital Information Design (DID) is primarily a business information management (BIM) model. As with any model it is used to help you to describe problems and test potential solutions. DID is not like any other method or framework model; it is independent of any other existing model or framework and does not claim to manage the entirety of the design of business information services. DID identifies useful and widely used best practices that are designed specifically for use in any phase of business information service development from idea, conception, specification, design, test, handover, service management and operation, or managing architectural issues or hardware and software installation. Primarily, DID was developed to manage the quality of information, and how to put it to good use. The DID model has been designed for you to identify what you need and when you need it when designing business information services and as a broad guide, identifies key points in existing frameworks that are particularly useful. The model is wholly independent of all other frameworks (including BiSL and BiSL Next in which the basic design is rooted). You can choose and use whatever you wish, the model will help you to assess the validity of your choice(s) and identify strengths and weaknesses in your approach.The DID model focuses on the common languages to describe key elements of design (need and value, mission and capability), key business information perspectives (business, information/data, services and technology) and the high-level domains (governance, strategy, improvement and operation) that must be managed in order to effectively run any business.DID helps you to identify only what you need to ensure that business information design reflects what is needed by your enterprise. The model can be used entirely separately from the framework level guidance discussed and it can be used at any level in the organization. The essentials of DID are explained in two books: this book, Foundation and the Practitioner book that will be published later.

Автор: Philip K. Moore; Matt Whiteman
Название: Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide
ISBN: 3319359096 ISBN-13(EAN): 9783319359090
Издательство: Springer
Рейтинг:
Цена: 279500.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states. Hydrogen sulfide has recently been discovered to be a naturally occurring gaseous mediator in the body. Over a relatively short period of time this evanescent gas has been revealed to play key roles in a range of physiological processes including control of blood vessel caliber and hence blood pressure and in the regulation of nerve function both in the brain and the periphery. Disorders concerning the biosynthesis or activity of hydrogen sulfide may also predispose the body to disease states such as inflammation, cardiovascular and neurological disorders. Interest in this novel gas has been high in recent years and many research groups worldwide have described its individual biological effects. Moreover, medicinal chemists are beginning to synthesize novel organic molecules that release this gas at defined rates with a view to exploiting these new compounds for therapeutic benefit.

Автор: Hideo Kimura
Название: Hydrogen Sulfide and its Therapeutic Applications
ISBN: 370911974X ISBN-13(EAN): 9783709119747
Издательство: Springer
Рейтинг:
Цена: 107130.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The metabolism of sulfur especially by sulfurtransferases had been intensively studied in mid 1900’s. Three enzymes, cystathionine ?–synthase (CBS), cystathionine ?–lyase (CSE) and 3-mercaptopyruvate sulfurtransferase (3MST) were found to have the capacity to produce H2S in vitro. However, H2S was recognized simply as a by-product of the metabolic pathways or as a marker for evaluating the activity of enzymes rather than as a physiological active molecule. In the late 1980’s relatively high concentrations of sulfide were measured in the brain that led to the successive studies of identifying the physiological functions of H2S. Recently, the steady-state concentrations of H2S have been re-evaluated and found to be much less than that initially measured. However, despite these differences, such re-evaluations served to further confirm the existence of H2S in mammalian tissues. H2S is produced in almost every organ and plays various roles such as neuromodulation, vasodilation, insulin release, inflammation, angiogenesis and cytoprotection. The unregulated production of H2S and improper responses of target molecules are involved in the pathogenesis of various diseases. This book focuses on these topics as well as on the recent progress in the biology and the therapeutic development of this molecule.

Автор: Philip K. Moore; Matt Whiteman
Название: Chemistry, Biochemistry and Pharmacology of Hydrogen Sulfide
ISBN: 3319181432 ISBN-13(EAN): 9783319181431
Издательство: Springer
Рейтинг:
Цена: 279500.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book puts hydrogen sulfide in context with other gaseous mediators such as nitric oxide and carbon monoxide, reviews the available mechanisms for its biosynthesis and describes its physiological and pathophysiological roles in a wide variety of disease states. Hydrogen sulfide has recently been discovered to be a naturally occurring gaseous mediator in the body. Over a relatively short period of time this evanescent gas has been revealed to play key roles in a range of physiological processes including control of blood vessel caliber and hence blood pressure and in the regulation of nerve function both in the brain and the periphery. Disorders concerning the biosynthesis or activity of hydrogen sulfide may also predispose the body to disease states such as inflammation, cardiovascular and neurological disorders. Interest in this novel gas has been high in recent years and many research groups worldwide have described its individual biological effects. Moreover, medicinal chemists are beginning to synthesize novel organic molecules that release this gas at defined rates with a view to exploiting these new compounds for therapeutic benefit.

Автор: Chandan K. Sen
Название: Redox Cell Biology and Genetics, Part B,353
ISBN: 0121822567 ISBN-13(EAN): 9780121822569
Издательство: Elsevier Science
Рейтинг:
Цена: 167030.00 T
Наличие на складе: Нет в наличии.
Описание: The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today-truly an essentipublication for researchers in all fields of life sciences.

Автор: Yong-Xiao Wang
Название: Pulmonary Vasculature Redox Signaling in Health and Disease
ISBN: 3319875078 ISBN-13(EAN): 9783319875071
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
Наличие на складе: Нет в наличии.
Описание: The main goal of this book is to form a high-quality platform in which well-known and emerging pioneering basic, translational and clinical scientists can present their latest, exciting findings in the studies of redox signaling in the pulmonary vasculature.

Автор: Yong-Xiao Wang
Название: Pulmonary Vasculature Redox Signaling in Health and Disease
ISBN: 3319632442 ISBN-13(EAN): 9783319632445
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The main goal of this book is to form a high-quality platform in which well-known and emerging pioneering basic, translational and clinical scientists can present their latest, exciting findings in the studies of redox signaling in the pulmonary vasculature.

Название: Oxidative Stress and Redox Signalling in Parkinson`s Disease
ISBN: 1782621881 ISBN-13(EAN): 9781782621881
Издательство: Royal Society of Chemistry
Рейтинг:
Цена: 189030.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides a thorough review of the latest research developments regarding the mechanisms by which oxidative stress and redox signalling mediate Parkinson`s Disease.

Автор: Bansal
Название: Redox Regulation and Therapeutic Approaches in Cancer
ISBN: 9819973414 ISBN-13(EAN): 9789819973415
Издательство: Springer
Рейтинг:
Цена: 149060.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book aims to provide an association of the major redox-sensitive pathways and networks involved in cancer. The initial chapter of the book discusses basic information about oxidative stress, its generation, and regulation (redox regulation or redox homeostasis) via cell signaling in normal and cancer cells. The book also explores antioxidants and metabolic events in cancer cells compared to normal cells. It further covers the application of nanoparticles in redox regulation in cancer cells. The role of redox regulation in cancer therapy, its influence, and its involvement in programmed cell death (PCD), metastasis, immune system, p53, and cell cycle/DNA damage repair pathways have been discussed in separate chapters. It further reviews the importance of dietary phytochemicals in redox regulation in normal and cancer pathophysiology. Towards the end, the book focuses on the role of redox balance, especially in ROS-dependent cellular processes in cancer stem cells.

Автор: Carsten Berndt, Christopher Horst Lillig
Название: Redox Regulation of Differentiation and De-differentiation
ISBN: 0367895668 ISBN-13(EAN): 9780367895662
Издательство: Taylor&Francis
Рейтинг:
Цена: 163330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Even before oxygen appeared in our athmosphere, redox reactions provided the energy for metabolic steps in the evolution of life. Redox modifications are now important in cellular functions including differentiation/development. This book compiles current knowledge regarding the roles of redox regulation in differentiation and de-differentiation.

Автор: ?akatay
Название: Redox Signaling and Biomarkers in Ageing
ISBN: 3030849678 ISBN-13(EAN): 9783030849672
Издательство: Springer
Рейтинг:
Цена: 130430.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book aims to present the age-related alterations in redox signaling networks and their diagnostic biomarkers in aging cells using multidisciplinary approach. Establishing sensitive and specific biomarkers of dynamic redox homeostasis is crucially important in the development of effective antiaging and senolytic interventions. Recent years have seen tremendous advances in the understanding of redox signaling events which highlight the process of aging and age-related pathologies. A major challenge in biological aging research is developing reliable biomarkers to determine the consequences of disrupted redox signaling networks long before the clinical diagnosis of age-related diseases is made. Therefore, we have chosen to concentrate on aging-induced aberrant redox signaling networks, their biomarkers, and pathological consequences in this book. Although oxidation is a natural metabolic process, the imbalance in the level of oxidants and antioxidants causes oxidative stress and eventually leads to inflammatory conditions, diabetes, neurodegenerative diseases, and cancer. Novel redox-sensitive biomarkers for the evaluation of aging-induced proteinopathies such as amyloid ? and tau proteins in Alzheimer's disease, ?-synuclein in Parkinson's disease, and islet amyloid polypeptides in type 2 diabetes mellitus recently drew the attention of researchers. Inside this textbook, readers will find comprehensive perspectives on the association between redox homeostasis and the aging process both at the molecular and clinical levels. Due to the inherent relationship between impaired metabolic activities and oxidative stress, the temporal interaction between intermediary metabolism and disturbed redox status can lead to greater susceptibility to aging-induced diseases and disorders, such as cardiovascular diseases, hypertension, and diabetes. This knowledge could be a key to continued research toward improving medication regimens such as in cancer and cardiovascular therapies, and procedural outcomes for patients. This book brings together current research evidence and knowledge on redox signaling and biomarkers in aging in chapters written by leading global experts in this rapidly evolving field. We hope that this textbook is of interest to a wide group of researchers, advanced students, scientifically curious non-specialist readers and clinicians alike.