How to Design and Implement Powder-to-Tablet Continuous Manufacturing Systems provides a comprehensive overview on the considerations necessary for the design of continuous pharmaceutical manufacturing processes. The book covers both the theory and design of continuous processing of associated unit operations, along with their characterization and control. In addition, it discusses practical insights and strategies that the editor and chapter authors have learned. Chapters cover Process Analytical Technology (PAT) tools and the application of PAT data to enable distributed process control.
With numerous case studies throughout, this valuable guide is ideal for those engaged in, or learning about, continuous processing in pharmaceutical manufacturing.
Discusses the development of strategy blueprints in the design of continuous processes
Shows how to create process flowsheet models from individual unit operation models
Includes a chapter on characterization methods for materials, the use of statistical methods to analyze material property data, and the use of material databases
Covers the evolving regulatory expectations for continuous manufacturing
Provides readers with ways to more effectively navigate these expectations
Автор: Shah B. Название: Textbook Of Pharmacognosy And Phytochemistry 2Ed ISBN: 9386217732 ISBN-13(EAN): 9789386217738 Издательство: CBS India Рейтинг: Цена: 36580.00 T Наличие на складе: Есть
Автор: Astrid Sigel, Eva Freisinger, Roland K.O. Sigel Название: Metal Ions in Bio-Imaging Techniques ISBN: 3110685566 ISBN-13(EAN): 9783110685565 Издательство: Walter de Gruyter Рейтинг: Цена: 285130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Volume 22, entitled Metal Ions in Bio-Imaging Techniques, of the series Metal Ions in Life Sciences deals with metal ions as tools in imaging. This dates back to the first half of the past century, when barium sulfate was orally given to patients undergoing X-ray examination. The use of contrast agents has since developed into a large interdisciplinary field encompassing not only medicine, but also chemistry, material sciences, physics, biology, engineering, and computer sciences. MILS-22 provides deep and current insights in 17 stimulating chapters on the new research frontiers of this fast growing field on bio-imaging ... and beyond. For example, adding bio-sensing yields theranostic agents, meaning diagnosis and therapy linked in the same molecule; ions of Gd, Mn, Fe, Co, Ir, 99mTc, etc., are involved. Other important topics are, e.g., metal complexes in paramagnetic Chemical Exchange Transfer (paraCEST), radiometals for Positron Emission Tomography (PET) imaging, or paramagnetic metal ion probes for 19F magnetic resonance imaging. MILS-22 is written by 57 internationally recognized experts from 12 countries, that is, from the US via Europe to China. The impact of this vibrant research area is manifested by more than 2300 references and nearly 120 figures, mostly in color, and several informative tables. To conclude, Metal Ions in Bio-Imaging Techniques is an essential resource for scientists working in the wide range from material sciences, enzymology, analytic, organic, and inorganic biochemistry all the way through to medicine including the clinic ... not forgetting that also excellent information for teaching is provided.
Автор: Brahmachari Название: Handbook of Pharmaceutical Natural Products : Wiley.- ISBN 9783527321483 СОЕДИНЕННОЕ КОРОЛЕВСТВО ISBN: 3527321489 ISBN-13(EAN): 9783527321483 Издательство: Wiley Рейтинг: Цена: 387500.00 T Наличие на складе: Поставка под заказ. Описание: In a classical alphabetical format, this two-volume reference covers more than 1000 painstakingly screened natural product structures. For each compound or compound class, a basic chemical characterization is given, followed by a description of the biological source and a discussion of their pharmaceutical potential as lead molecules for new drugs.
Автор: Christine Bladon Название: Pharmaceutical Chemistry: Therapeutic Aspects of Biomacromolecules ISBN: 0471496375 ISBN-13(EAN): 9780471496373 Издательство: Wiley Рейтинг: Цена: 90760.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Explores the way in which peptides, proteins, nucleic acids and carbohydrates use therapeutically. With help of illustrations, this book covers both compounds and how therapeutics exert their influence through an understanding of biological processes.
Автор: Mikolaj Tosto Название: Marine Glycobiology: Principles & Applications ISBN: 1681176890 ISBN-13(EAN): 9781681176895 Издательство: Gazelle Book Services Рейтинг: Цена: 230210.00 T Наличие на складе: Невозможна поставка. Описание: Marine glycobiology is an emerging and exciting area in the field of science and medicine. Glycobiology, which is the study of the structure and function of carbohydrates and carbohydrate containing molecules, is fundamental to all biological systems. Progress in glycobiology has shed light on a range of complex biological processes associated with, disease and immunology, molecular and cellular communication, and developmental biology. Marine Glycobiology: Principles and Applications revolutionise the concept of marine glycobiology, focusing on the latest principles and applications of marine glycobiology and their relationships. In fact, glycobiology combines all branches of biomedical research, revealing the vast and diverse forms of carbohydrate structures that exist in nature. Advances in structure determination have enabled scientists to study the function of complex carbohydrates in more depth and to determine the role that they play in a wide range of biological processes. Glycobiology research in marine systems has primarily focused on reproduction, in particular for what concern the chemical communication between the gametes. There is an established, if rather modest, tradition of glycobiology research in marine systems that have primarily focused on reproduction, biofouling, and chemical communication. The current status of marine glycobiology is mainly descriptive with very limited progress on structural clarification and the consequent definition of specific functional roles beyond a small number of classical examples, (eg: induction of the acrosome reaction in echinoderms). However, with recent advances in analytical instrumentation, there is now the capacity to begin to characterise marine glycoconjugates, many of which will have potential biomedical and biotechnological applications. This title will highlight the fundamental importance of glycobiology for many biological processes in marine organisms and will draw upon the best defined systems. These systems therefore may prove genuine candidates for full carbohydrate characterisation.
Автор: Merkus Название: Particles and Nanoparticles in Pharmaceutical Products ISBN: 3319941739 ISBN-13(EAN): 9783319941738 Издательство: Springer Рейтинг: Цена: 107130.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This edited volume brings together the expertise of numerous specialists on the topic of particles - their physical, chemical, pharmacological and toxicological characteristics - when they are a component of pharmaceutical products and formulations.
Автор: Hedaya Mohsen A. Название: Basic Pharmacokinetics, Second Edition ISBN: 1439850739 ISBN-13(EAN): 9781439850732 Издательство: Taylor&Francis Рейтинг: Цена: 102070.00 T Наличие на складе: Нет в наличии. Описание: Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. Accessible to a wide variety of readers, this volume demonstrates the quantitative pharmacokinetic relations and the interplay between pharmacokinetic parameters. Accompanying the book are downloadable resources with self-
Автор: Amit Singh Название: Stimuli-Responsive Drug Delivery Systems ISBN: 1788011139 ISBN-13(EAN): 9781788011136 Издательство: Royal Society of Chemistry Рейтинг: Цена: 223870.00 T Наличие на складе: Нет в наличии. Описание: This book provides a comprehensive account on the design, materials chemistry, and application aspects behind these novel stimuli-responsive materials.
Автор: S. Narasimha Murthy Название: Dermatokinetics of Therapeutic Agents ISBN: 1138114588 ISBN-13(EAN): 9781138114586 Издательство: Taylor&Francis Рейтинг: Цена: 81650.00 T Наличие на складе: Невозможна поставка. Описание:
Novel drug delivery technologies strive to bypass challenging biological layers to elicit desired pharmacological activity. The skin, one of our key defensive barriers, allows certain topically applied substances and toxins to pass. The dermatokinetics of a drug determines the efficacy of treatment of skin disorders.
Presenting the first comprehensive reference on this important area of research, Dermatokinetics of Therapeutic Agents includes a general overview of the theoretical as well as practical aspects of dermatokinetics and addresses the impact of a drug delivery system on the dermatokinetics of drugs. Chapters and illustrations cover introductory aspects and the significance, methods, and models used in dermatokinetic studies of therapeutic agents.
Topics include:
Theoretical Models for Dermatokinetics of Therapeutic Agents
Drug Delivery Approaches to Modulate Dermatokinetics of Drugs
Conventional Methods of Cutaneous Drug Sampling
Cutaneous Microdialysis
Sampling Substrates by Skin Permeabilization
Spectroscopic Techniques in Dermatokinetics Studies
Regulatory Perspective of Dermatokinetic Studies
Автор: Watson, David G. (Senior Lecturer in Pharmaceutical Sciences, Strathclyde Institute of Pharmaceutical and Biomedical Sciences, University of Strathcly Название: Pharmaceutical and Medicinal Chemistry. Elsevier,2011 ISBN: 9780443072321\Давид Уотсон:Фармацевтическая и лекарственная химия, Элзивир,2011 ISBN: 0443072329 ISBN-13(EAN): 9780443072321 Издательство: Elsevier Science Рейтинг: Цена: 49390.00 T Наличие на складе: Поставка под заказ. Описание: Intends to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. This book emphasizes on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target.
