Monte Carlo Simulation for the Pharmaceutical Industry, Chang, Mark
Автор: Watson David G. Название: Pharmaceutical Analysis. 5 ed ISBN: 0702078077 ISBN-13(EAN): 9780702078071 Издательство: Elsevier Science Рейтинг: Цена: 35370.00 T Наличие на складе: Есть Описание: Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals. The mathematics involved is notoriously difficult, but this much-praised textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Two new chapters have been added to the new edition covering methods used in the quality control of biotechnologically produced drugs, and electrochemical biosensors. There is continuous learning reinforcement throughout the book by way of worked calculation examples and self-assessment test questions. Worked calculation examples Self-assessment Additional problems (self tests) Practical boxes Key points boxes Two new chapters: Chapter 16 Methods used in the quality control of biotechnologically produced drugs Chapter 17 Electrochemical biosensors
Автор: Katja Strohfeldt-Venables Название: Essentials of Inorganic Chemistry: For Students of Pharmacy, Pharmaceutical Sciences and Medicinal Chemistry.- Wiley, 2015 ISBN: 0470665580 ISBN-13(EAN): 9780470665589 Издательство: Wiley Рейтинг: Цена: 49580.00 T Наличие на складе: Поставка под заказ. Описание: A comprehensive introduction to inorganic chemistry and, specifically, the science of metal-based drugs, Essentials of Inorganic Chemistry describes the basics of inorganic chemistry, including organometallic chemistry and radiochemistry, from a pharmaceutical perspective.
Автор: Watson, David G. (Senior Lecturer in Pharmaceutical Sciences, Strathclyde Institute of Pharmaceutical and Biomedical Sciences, University of Strathcly Название: Pharmaceutical and Medicinal Chemistry. Elsevier,2011 ISBN: 9780443072321\Давид Уотсон:Фармацевтическая и лекарственная химия, Элзивир,2011 ISBN: 0443072329 ISBN-13(EAN): 9780443072321 Издательство: Elsevier Science Рейтинг: Цена: 49390.00 T Наличие на складе: Поставка под заказ. Описание: Intends to define the area of pharmaceutical chemistry as distinct from medicinal chemistry. This book emphasizes on the physicochemical properties of drug molecules and, in so far as they are known, the way that these properties govern the interaction of the drug with its target.
Автор: Watson, David G. Название: Pharmaceutical Analysis International Edition 5 : Elsevier Science.- ISBN 9780702078088 СОЕДИНЕННОЕ КОРОЛЕВСТВО ISBN: 0702078085 ISBN-13(EAN): 9780702078088 Издательство: Elsevier Science Рейтинг: Цена: 31430.00 T Наличие на складе: Поставка под заказ. Описание: Pharmaceutical analysis determines the purity, concentration, active compounds, shelf life, rate of absorption in the body, identity, stability, rate of release etc. of a drug. Testing a pharmaceutical product involves a variety of analyses, and the analytical processes described in this book are used in industries as diverse as food, beverages, cosmetics, detergents, metals, paints, water, agrochemicals, biotechnological products and pharmaceuticals.
The mathematics involved is notoriously difficult, but this much-praised textbook, now revised and updated for its fifth edition, guides a student through the complexities with clear writing and the author's expertise from many years' teaching pharmacy students. Two new chapters have been added to the new edition covering methods used in the quality control of biotechnologically produced drugs, and electrochemical biosensors. There is continuous learning reinforcement throughout the book by way of worked calculation examples and self-assessment test questions.
Автор: Lal, H. Название: Essentials of Pharmaceutical Biochemistry: CBS Publishers & Distributrors, 2019.- ISBN: 9789386478580 /Основы фармацевтической биохимии, включая практические упражнения ISBN: 9386478587 ISBN-13(EAN): 9789386478580 Издательство: CBS India Рейтинг: Цена: 31350.00 T Наличие на складе: Нет в наличии. Описание: This book includes all of the theory as well as the practical side of pharmaceutical biochemistry, presented in a simple, yet comprehensive, way. It includes chapters on topics such as biomolecules, biogeneratics, energy rich compounds, biological oxidation, the catalytic role of enzymes, the importance of enzyme inhibitors in the design of new drugs, and therapeutic and diagnostic applications of enzymes.
Название: Simulation for Designing Clinical Trials ISBN: 0367395606 ISBN-13(EAN): 9780367395605 Издательство: Taylor&Francis Рейтинг: Цена: 65320.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation practices. The book discusses how to design clinical trials according to their probability for success, techniques to define distributions of virtual subjects' characteristics, methods to determine the sensitivity of the trial design, and the population relationship between dosing schedules and patient response.
Автор: Steven P. Millard; Andreas Krause Название: Applied Statistics in the Pharmaceutical Industry ISBN: 144193166X ISBN-13(EAN): 9781441931665 Издательство: Springer Рейтинг: Цена: 144410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Providing a general guide to statistical methods used in the pharmaceutical industry, and illustrating how to use S-PLUS to implement these methods, the book explains why S-PLUS is a useful software package and discusses the results and implications of each particular application.
The high failure rate in the pharmaceutical industry has positioned biomarkers and personalized medicine in the frontline as possible solutions. If executed right, biomarkers and companion diagnostics (CDx) can potentially help the drug industry enhance the probability of success, accelerating time to market, and, more importantly, benefit patients by supporting accurate diagnosis and selection of the most effective and least toxic therapies. Biomarkers, Diagnostics, and Precision Medicine in the Drug Industry aims to examine the challenges and limitations in biomarkers and laboratory tests. It also offers advice on best practices to ensure proper application of biomarkers and bridges the gap between diagnostic business development claims and real-life deliverables. The book covers biomarkers for different purposes, provides examples from different technologies which includes standard-of-care approved assays as well as for-investigational-use and for-research-use-only assays. It also includes new data for biomarkers in different therapeutic indications and offers case studies and practical examples. Biomarkers, Diagnostics, and Precision Medicine in the Drug Industry serves as a reference to drug developers, IVD providers, healthcare givers, academics, and researchers for best practices to help increase the probability of success.
Provides the unique insight of an expert with extensive experience in diagnostics and clinical laboratory on one side and drug discovery and development on the other side
Addresses the challenges of drug development and precision medicine and suggests how to eliminate or mitigate these challenges through better utilization of biomarkers and diagnostics in drug development and patient management
Features case studies and real-life examples from different classes of biomarkers on different platforms for different therapeutic areas
Автор: Shields, Kristine E. Название: Pregnancy and the Pharmaceutical Industry ISBN: 0128185503 ISBN-13(EAN): 9780128185506 Издательство: Elsevier Science Рейтинг: Цена: 107740.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Pregnancy and the Pharmaceutical Industry: The Movement Toward Evidence-based Care for Pregnant Women explores the issues surrounding the decision to undertake clinical trials with pregnant women. There is currently a lack of data on the safety and effectiveness of medications when they are used during pregnancy, and it is impossible to extrapolate that information from drug studies on men and nonpregnant women. A majority of pregnant women confront a medical condition during their pregnancy, from simple pain to on-going or new medical issues to life-threatening emergencies. New draft guidance from the FDA offers specific recommendations to include pregnant women in drug studies that minimize risk and maximize therapeutic data. This book quantifies the current absence of pregnant women in drug studies and identifies the ethical issues, barriers, and litigation fears, but also the opportunities articulated by physicians, lawyers, ethicists, and other stakeholders in and around the pharmaceutical industry. Pregnancy and the Pharmaceutical Industry: The Movement Toward Evidence-based Care for Pregnant Women explores the views of the pharmaceutical industry on the inclusion of pregnant women in clinical studies, as well as presents information for stakeholders on the ethical rationale, context, and details to adapt to this new FDA guidance. Those in the pharmaceutical industry, IRB members, who approve or deny the drug study plan, doctors, nurses, and midwives working in obstetrics or involved in conducting studies at their institutions will find this book an essential resource.
Explores the medical, ethical, scientific, and legal rationales behind the inclusion of pregnant women in drug studies
Describes how pharma and biotech companies can safely implement the new FDA guidance and begin to include pregnant women in drug testing
Shares views from pharmaceutical industry insiders about company risks, reluctance to implement the guidance, but the ultimate need to include pregnant women in studies
Автор: Ostrove, Steven Название: Ostrove - Equipment Qualification in the Pharmaceutical Industry ISBN: 0128175680 ISBN-13(EAN): 9780128175682 Издательство: Elsevier Science Рейтинг: Цена: 110030.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Equipment Qualification in the Pharmaceutical Industry provides guidance and basic information for the preparation of a quality qualification program. It has been noted that there is a general lack of understanding in the industry, especially for those new to the industry, as to what constitutes a compliant qualification program. Even experienced professionals have felt a lack of security in reaching a compliant state. This book outlines a guideline for the preparation and execution of qualification protocols including the installation (IQ), operational (OQ), and performance (PQ) protocols. It discusses the importance of related qualification programs (e.g., quality systems, commissioning, computer system, and cleaning) and how to incorporate them into a fully compliant qualification program. Furthermore, it provides matrices of what could be included in each type of protocol for major types of process equipment. While primarily for people entering the pharmaceutical industry, those established in the field will benefit from the multiple examples and matrices as well as integration of related systems.
Equipment Qualification in the Pharmaceutical Industry provides students and pharmaceutical scientists a guideline for the preparation and execution of qualification (installation, operational, and performance) protocols.
Incorporates good manufacturing processes into a compliant qualification program
Provides examples of protocol layout
Includes matrices for major process equipment, installation quality, operational quality, and performance quality requirements
Автор: Christoph Saal, Anita Nair Название: Solubility in Pharmaceutical Chemistry ISBN: 3110545136 ISBN-13(EAN): 9783110545135 Издательство: Walter de Gruyter Цена: 127630.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This book describes the physicochemical fundamentals and biomedical principles of drug solubility. Methods to study and predict solubility in silico and in vitro are described and the role of solubility in a medicinal chemistry and pharmaceutical industry context are discussed. Approaches to modify and control solubility of a drug during the manufacturing process and of the pharmaceutical product are essential practical aspects of this book.
Название: The Clinical Research Process in the Pharmaceutical Industry ISBN: 0367451883 ISBN-13(EAN): 9780367451882 Издательство: Taylor&Francis Рейтинг: Цена: 63280.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book examines the sequence of events and methodology in the industrial clinical research process; a reference for multidisciplinary personnel. It is the conceptual framework involving the philosophical, economic, political, historical, regulatory, planning, and marketing aspects of the process.
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